In reading through some of the threads lately, it seems like a lot of guys are having some odd effects from Ostarine, namely gyno and erectile dysfunction, even after full PCT's.
now, Ostarine is suppresive to the HPTA. 3 mg has been shown to be moderately suppressive to the HPTA.
http://www.ergo-log.com/enobosarmtrial.html
but it does not aromatize to estrogen or convert to DHT. in fact, the above study shows a significant reduction of estradiol while on cycle.
so how to we get gyno? the only theory I've read there, is that Ostarine lowers SHBG, thereby freeing estrogen to bind to the ER.
and why the ED? my assumption is that it's partially due to a drop in DHT (although the lowered testosterone and E2 levels undoubtedly would affect this as well).
^so, how are these issues managed the most effectively?
now, Ostarine is suppresive to the HPTA. 3 mg has been shown to be moderately suppressive to the HPTA.
http://www.ergo-log.com/enobosarmtrial.html
but it does not aromatize to estrogen or convert to DHT. in fact, the above study shows a significant reduction of estradiol while on cycle.
so how to we get gyno? the only theory I've read there, is that Ostarine lowers SHBG, thereby freeing estrogen to bind to the ER.
and why the ED? my assumption is that it's partially due to a drop in DHT (although the lowered testosterone and E2 levels undoubtedly would affect this as well).
^so, how are these issues managed the most effectively?