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R-ALA and liver

Buc4Life04

Member
I read every where to take rala with meth cycles but i would like to know
the reason behind this? what it does ect?
 
ALA is a very versatile (water soluble and fat soluble) antioxidant. Studies have shown it's protective effects on the liver, and actually found more effetive than silymarin (milk thistle). In certain cases of toxicity, hospitals will administer ALA intravenously. Here's one study showing the efficacy of ALA administered orally on hepatotoxicity...

Protective effect of alpha-lipoic acid against chloroquine-induced hepatotoxicity in rats.

Pari L, Murugavel P.

Department of Biochemistry, Faculty of Science, Annamalai University, Annamalai Nagar, Tamil Nadu 608 002, India.
Oral administration of a-lipoic acid, a metavitamin, was investigated for its possible hepatoprotective effect in Wistar rats against chloroquine-induced toxicity. Rats were treated orally with alpha-lipoic acid (10, 30 and 100 mg x kg(-1) day(-1)) for 7 days before a single oral administration of chloroquine (970 mg x kg(-1) day(-1)) and alpha-lipoic acid treatment was continued for three more days. The increased level of serum enzymes (aspartate transaminase, alanine transaminase and alkaline phosphatase), bilirubin, lipids and plasma thiobarbituric acid-reactive substances (TBARS) and hydroperoxides observed in rats treated with chloroquine were very much reduced in rats treated with alpha-lipoic acid plus chloroquine. A significant decrease in plasma antioxidants such as reduced glutathione (GSH), vitamin C and vitamin E were observed in chloroquine-treated rats when compared with control rats. Administration of alpha-lipoic acid significantly improved the levels of plasma antioxidants GSH, vitamin C and vitamin E in chloroquine-treated rats. In the case of 100 mg x kg(-1) day(-1) the effect was highly significant compared with the other doses (10 and 30 mg x kg(-1) day(-1)). The results of the study revealed that alpha-lipoic acid could offer protection against chloroquine-induced hepatotoxicity. alpha-Lipoic acid had a better protective effect when compared with silymarin, a reference drug.
 
It's because sledge says so. lol

He had someone check liver tests and saw something like 20-30% improvement in values with a good dose of r-ala (600-1200mg ED).
 
Dosage?

I've seen anywhere from 300 mg a day (1fast R-ALA is 3 x 100mg) and up. Is there a more exact recommended dosage while on methlys?
 
While were on this topic are asprin tynolect bad on liver while takin meths
i think i read that but wanted to make sure bc i got some killer tendonitis
and i guess ill just have to deal with it if i cant take asprin.
 
it's tylenol (acetaminophen) that's hepatotoxic

people also have to be careful with vicodins and other combo drugs that have acetaminophen in them. vicodin iirc is 5mg hydrocodone and 500 mg acetaminophen
 
should r-ala be taken on empty stomach or with food? or does it matter? any disadvantage to taking r-ala?
 
you should take it with food. It is also very useful in giving your body the most from each meal. Basically it helps with nutrient uptake.
 
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