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Pure PF3: Patent Pending Pharma Protein - Loggers Needed

chefbo said:
got my pf3 but am missing the leucine. packing slip had it listed but nothing there. can someone help me out and track this to see what happened? should I start without it or wait? somebody help me out here.
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Sent an email to try and get this figured out for you.
 
Dalton. . .
 
Look what was in the mail today:

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Very generous of MAN. Will get the log running tomorrow morning.
 
How will u guys be marketing this in a brick and mortar store or will this be internet only?
 
Received my shipments today. The log is started. Can't figure out how to link it since I use my phone and not my computer. The name is : Pampers gets MANly with PF3.
 
pampers938 said:
Received my shipments today. The log is started. Can't figure out how to link it since I use my phone and not my computer. The name is : Pampers gets MANly with PF3.
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Click on the thread title in black. Then on the next screen, hit the bottom right box with the arrow for "copy link." Then paste in your post.
 
My log is here:

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Has anyone had negative sides.... I used it this morning and well not so good. Any stomach issues, lightheaded or disoriented?
 
All loggers check your PM's :)

And scratch the time table I listed in the message, Timeframe will be by Thursday of NEXT WEEK (September 5th) :D Sorry about the confusion, lost track of dates
 
allnatural923 said:
All loggers check your PM's :)

And scratch the time table I listed in the message, Timeframe will be by Thursday of NEXT WEEK (September 5th) :D Sorry about the confusion, lost track of dates
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Thanks for the update. This gives me more time.

I'll get my log up and running later on tonight.
 
Just read the write up on NP. Disappointed to say the least. But to give you the benefit of the doubt, I'd be very interested in hearing how MAN overcame the difficulty of orally dosing peptide hormones effectively, seeing as they get digested and treated just like any other peptide in the gut? Do you have data demonstrating your 'bio-active' fractions even reach the blood stream intact?
 
Resolve said:
Just read the write up on NP. Disappointed to say the least. But to give you the benefit of the doubt, I'd be very interested in hearing how MAN overcame the difficulty of orally dosing peptide hormones effectively, seeing as they get digested and treated just like any other peptide in the gut? Do you have data demonstrating your 'bio-active' fractions even reach the blood stream intact?
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well, in terms of the bioactivity you mention, there is tremendous bioactivity on the GI tract itself which results in a significant anti-inflammatory effect (through reducing cytokines) on the GI. the presence of cytokines in the gi and throughout the body are the result of chemicals, stress, pathogens ect. interestingly, the ability of IGF-1 to synthesize protein is impaired by a cytokine increase. cytokines also negatively impact absorption and tissue repair.

I agree with you that any peptides absorbed with be broken down into the constituent aminos. the bioactivity upon the Gi track, however, will allow bioactive proteins that are made by the body to be used for other purposes
 
thescience said:
well, in terms of the bioactivity you mention, there is tremendous bioactivity on the GI tract itself which results in a significant anti-inflammatory effect (through reducing cytokines) on the GI. the presence of cytokines in the gi and throughout the body are the result of chemicals, stress, pathogens ect. interestingly, the ability of IGF-1 to synthesize protein is impaired by a cytokine increase. cytokines also negatively impact absorption and tissue repair.

I agree with you that any peptides absorbed with be broken down into the constituent aminos. the bioactivity upon the Gi track, however, will allow bioactive proteins that are made by the body to be used for other purposes
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So, you are claiming your oral peptide product has effects on the GI tract specifically that make it superior to other options? Do you have any data to support this? Are the doses provided in PF3 sufficient to what is supported in literature? Is that anti-inflammatory effect known to occur in the gut lumen? Do cell surfaces facing the gut lumen even express receptors for those peptides at appreciable levels? I know the mucosa has rapid turnover and robust endocrinology, but those endo signals are typically recognized to come from the basal side of things, where bloodflow is.

I could see how reducing inflammation would be beneficial for those with auto-immune issues or similar problems, but for the average lifter, is that effect significant?

Is that the only benefit you are claiming? I saw no mechanisms listed in the write-up?

Your last sentence suggests that you know full well none of the peptides in PF3 are getting into the blood stream, where they would have the largest effect. If all PF3 does is reduce inflammation, how is it superior to just popping some aspiring and eating healthy (i.e. cheaper anti-inflammatory options)?
 
I could see how reducing inflammation would be beneficial for those with auto-immune issues or similar problems, but for the average lifter, is that effect significant?
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inflammation is alot more pervasive than its occurance in auto-immune disease. with regard to lifters, theres alot of thought that inflammation plays a large role in several kinds of DOMS, hence the creation of products like wobenzyme ect targeted at athletes.

with reference to how effective this substance is for its intended effects on the GI, i would posit that this is the exact same compound in hospitals, where it passes muster for these purposes on people with severely comprimized health. the doses they use vary for the kind of treatment they are using it for. i know its used for cancer (post chemo) and its coming out soon to be used for IBS-D



Is that the only benefit you are claiming?
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i dont diminish the reduction of cytokines as anything resulting in a singular effect, as inflammation can affect many, many body systems. the ad for pf3 states it is intended for rapid recovery, increased strengh, and others which are consistant with what the first round beta-testers reported at only 2.5g's (as opposed to pf3's 25 day supply of 5g dosing available.


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If all PF3 does is reduce inflammation,
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the inflammation effect im referring to comes from the IGg. there are many other substances is PF3:

here is something on orally ingested bioactives:
Similar to lactoferrin, IGF-1 stimulates the growth and proliferation of the mucosa that results
in a larger surface area for nutrient absorption in the gut as well as a more developed barrier function.




how is it superior to just popping some aspiring and eating healthy (i.e. cheaper anti-inflammatory options)?
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well, i cant think of any foods/aspirins that exhibit the medical-grade effects effects like this extract does in how hospitals are using it

Your last sentence suggests that you know full well none of the peptides in PF3 are getting into the blood stream, where they would have the largest effect
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i didnt suggest anything; i flat out agreed with you that the specific peptides we are talking about dont just end up in the bloodstream intact
 
Got the log going. (That's what she said.)

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Thanks again for the free setup. Candy Grape tastes like pixie sticks of yesteryear!
 
I like that "poop" is a palindrome.
 
I'm dosing the fermented leucine at night.
 
broken bottle said:
I think this product makes me poop.
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bb. misfit: let me know if you are more or less able to determine if this is happening from your testing as, depending on the kind of increase in motility we are talkiing about, it may be advisable to reduce dosage to the one scoop a day or drink more water ect until things normalize. let me know also of any changes from that status with your bowels as the days go by. Immunoglobins, lactoferrin ect have tremendous anti-pathogenic properties. the studies ive seen on the main ingredient in pure Pf3 in pharma on ibs-d (ibs that is predominantly diarrhea) would not shed any light as to any increase in bowel motility at the start (when pathogens were being removed) as the subject had pre-existing chronic diarrhea, but by the end of the study, many had REDUCED frequency: in a Randomized, double- blind, placebo- controlled, single site, 6 week study N=66 patients diagnosed with IBS-D Placebo, "***" 5 g/day or "***" 10 g/day10 g/d "***"group had a reduction in days with loose stools (p = 0.011), abdominal pain (p = 0.008), urgency (p = 0.050), bloating (p = 0.044); flatulence (p = 0.003); and any symptom (p = 0.009). 5 g/day "***" group experienced reductions in days with flatulence (p = 0.018), incomplete evacuation (p = 0.020), and any symptom (p = 0.010). "***" = same compound found in PF3
 
I use 1 scoop a day immediately post workout, followed by a meal. I've noticed abdominal pain, flatulence, and a BM after use. Been drinking plenty of water. I will see if it keeps happening.
 
broken bottle said:
I use 1 scoop a day immediately post workout, followed by a meal. I've noticed abdominal pain, flatulence, and a BM after use. Been drinking plenty of water. I will see if it keeps happening.
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ok. yeah please keep me posted. how often do you usually have bm's in a day? how often is it happening now? misfit mentioned in another thread he had just been on a round of antibiotics, which is really rough on the bowel ecology. am i correct in assuming you havent had any such issues recently?
 
thescience said:
ok. yeah please keep me posted. how often do you usually have bm's in a day? how often is it happening now? misfit mentioned in another thread he had just been on a round of antibiotics, which is really rough on the bowel ecology. am i correct in assuming you havent had any such issues recently?
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Id say that the stool is softer and instead of good solid go its two at a longer pace... If that makes sense. And gotta have a couple extra wipes, now my TP cost is going up. Dang the things we must sacrifice for a better body.

On another note I state in my log that I believe the extreme lightheaded, disorientation and violent throwing up was a Combe of what I was taking. I had double dose of a preworkout and I was also using a PH. I have not experienced any sides since. Now I am just looking for growth.
 
Got my stash (much thx) earlier in the week. Yesterday mixed Grape and some leucine but unfortunately no scooper in my leucine, did the old finger dive but nothing. I mixed with with a shaker ball and as others stated there is alot of foam and also alot of white bubbles stuck to the sides when done.

Taste was good. Planned on hitting it hard today but woke up queasy and fever...stay tuned.
 
I got a fever, and the only prescription is more cowbell! And PF3.

Hope you feel better soon.
 
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