Everything except the acid reflux: diarrhea, bloating, gas, and not to be gross, but I could physically see it in the toliet
If i eat a protein & carb meal, i.e. really low fat, no problem. If I eat a protein and fat meal with or around a prime dose, watch out! If I eat a protein and fat meal without prime, and a atleast 4-6 hours away from a prime dosage, I'm fine.