Potassium nitrate

Cjg

Well-known member
How safe is potassium nitrate for human consumption? Being its used in fertilizer and gun powder? Just curious....
 
At what dosage? If it's in the proper dosing range and as long as it's coingested with 250-500mg of vitamin c it's fine. Obviously take time off intermittently. There are a lot of threads where coop and others chimed in. I'll try and dig them up later.
 
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According this its acutely toxic in rats at 3750mg/kg. Human equivalent toxic dose for a 200lb guy would be approximately 54.7g

The carcinogenic issues are related to the nitrosamines that result from the conversion of nitrates once consumed. That is why the antioxidant Vitamin C is consumed concurrently with reasonable doses. I believe about a gram of net nitrate is what's reasonable.

I use NO3 and it is 66% nitrate. I dose it at 1.6g to achieve 1g.
 
I've used iFN potassium nitrate before with no issues whatsoever. Only amazing pumps ;)
 
Yea, I know, a couple or more threads.

The concern is in regard to nitrosamines. Nitrosamines can be carcinogenic. They are a byproduct of nitrates. Nitrates themselves are not carcinogenic. As stated, one concurrently consumes the antioxidant vitamin C to combat the nitrosamines. I also use NAC but for multiple reasons.

http://anabolicminds.com/forum/supplements/260645-coops-corner-9-a.html
http://anabolicminds.com/forum/supplements/247208-next-pes-insider-96.html#post4702487
http://anabolicminds.com/forum/supplements/247935-nitrates-cancer.html#post4448136
http://anabolicminds.com/forum/supplements/232537-nitrate-discussion.html#post4067794
http://anabolicminds.com/forum/supp...95-pes-preworkout-enhanced-2.html#post3834317
 
The primary thing to be concerned about with KNO[SUB]3[/SUB] is purity -- "stump killer" and other industrial-grade blends will be mostly what you want, but you have no idea or guarantee what the rest is--and it could be very bad. "99% pure" doesn't help if it's "1% arsenic." This is why food or medical grades are needed for human consumption scenarios.

The nitrosamine thing is indeed a concern, but any reducing agent at a reasonable level alongside it all but eliminates that worry. Vitamin C is the reference reducing agent and nearly every marketed product has a large jolt of that along with the nitrate.

To further alleviate the carcinogen concerns, you don't hear people talking about beets, spinach, or arugula as being killers. They're fantastic sources of nitrates (seriously, if you can stomach a big bowl of arugula, try it sometime) but also have robust amounts of concomitant reducing agents.
 
People use this stuff to make explosives. Never it used it myself because of the fear of it dropping BP too much and passing out. I've always been a bit weary of nitrates use in supplements. Then again I've got zero interest in products designed to give you a pump. The majority of products that contain nitrates stacked in a prop blend that I've tried just made me tired. The nitrate craze seems to have died down a bit though.
 
T-Bone said:
People use this stuff to make explosives. Never it used it myself because of the fear of it dropping BP too much and passing out. I've always been a bit weary of nitrates use in supplements. Then again I've got zero interest in products designed to give you a pump. The majority of products that contain nitrates stacked in a prop blend that I've tried just made me tired. The nitrate craze seems to have died down a bit though.
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Have you tried it for cardio?
 
Never used it until I tried MaxOut..gotta say it gives insane pumps
 
Cjg said:
Sound like something to stay away from....
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Personal choice.

I feel like the negatives from nitrates are mediated quite well when combined with vit C or another anti-oxidant of choice.
 
Yea.. Didn't realize it was in max out . And I've taken that plenty of times with no negatives..
 
T-Bone said:
People use this stuff to make explosives. Never it used it myself because of the fear of it dropping BP too much and passing out. I've always been a bit weary of nitrates use in supplements. Then again I've got zero interest in products designed to give you a pump. The majority of products that contain nitrates stacked in a prop blend that I've tried just made me tired. The nitrate craze seems to have died down a bit though.
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I've never heard of potassium nitrate, but then again I don't buy into 'pump' or gimmick type products that don't significantly increase performance. Sounds like more of a vanity supplement just for the gym? And a carcinogenic one at that? Wtf is wrong with people...
 
David Dunn said:
no disrespect intended but simply because a manufacturers sells it doesn't make it safe. As well, because no one has negative feedback doesn't either.

I'm kind of a fan of data and science in that regard.
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Your logic has no power here. David the Gray.
 
Potassium nitrate can pose a number of health risks. When inhaled, it may cause respiratory problems, including coughing and shortness of breath. Skin or eye contact may result in irritation such as redness, itching and pain. If ingested, a number of problems can occur, including blue lips and fingernails, abdominal pain, dizziness, nausea, vomiting and diarrhea. Mallinckrodt Baker Chemicals advises that workers wear masks, gloves and safety goggles when handling potassium nitrate powder. First aid measures involve removing exposed persons to fresh air, flushing any areas of contact with water, inducing vomiting if potassium nitrate ingestion has occurred, and seeking immediate medical attention.
 
You guys need to use Pubmed before making your assumptions. There's a plethora of data that supports improved endurance, intra set recovery, performance etc.. It's not just a pump product.
 
David Dunn said:
no disrespect intended but simply because a manufacturers sells it doesn't make it safe. As well, because no one has negative feedback doesn't either.

I'm kind of a fan of data and science in that regard.
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I agree that people should be skeptical. I think its a supplement users job to be informed about what they ingest.

KN03 is very safe when provided in 600-1200mg doses. I don't think higher doses are needed. As shown above, you'd need >50g to have actute issues. the msds looks scary, but so does caffeines:


Potential Acute Health Effects:
Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Severe over-exposure can result
in death.
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: 3 (Not classifiable for human.) by IARC. MUTAGENIC EFFECTS: Mutagenic for mammalian
somatic cells. Mutagenic for bacteria and/or yeast. TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY:
Not available. The substance may be toxic to heart, gastrointestinal tract, central nervous system (CNS). Repeated or
prolonged exposure to the substance can produce target organs damage. Repeated exposure to a highly toxic material may
produce general deterioration of health by an accumulation in one or many human organs.
Section 4: First Aid Measures
p. 2
Eye Contact:
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Cold water may be used. WARM water MUST be used. Get medical attention.
Skin Contact:
In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove contaminated
clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention.
Serious Skin Contact:
Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate medical
attention.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical
attention.
Serious Inhalation:
Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. Seek
medical attention.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention immediately.
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David Dunn said:
You guys need to use Pubmed before making your assumptions. There's a plethora of data that supports improved endurance, recovery, performance etc.. It's not just a pump product.
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Lord help us. I feel like I am on bb.com right now.
 
Is it really worth the risk/reward ratio?

I can think of a handful of things that increase performance / endurance tremendously without any potential carcinogenic sides, or without having to worry about warding off metabolites and hoping that vitamin C will actually work to remove carcinogenic byproducts. I'm not sure why anyone would want to put themselves in a situation where they have to do that in the first place.

Maybe it's me, but I like to play it safe, especially where carcinogens are concerned. I'll stick with inj l-carnitine which is perfectly legal, safe, and tremendously effective for cell volumization, endurance, and performance (the list goes on).
 
Gutterpump said:
Is it really worth the risk/reward ratio?

I can think of a handful of things that increase performance / endurance tremendously without any potential carcinogenic sides, or without having to worry about warding off metabolites and hoping that vitamin C will actually work to remove carcinogenic byproducts. I'm not sure why anyone would want to put themselves in a situation where they have to do that in the first place.

Maybe it's me, but I like to play it safe, especially where carcinogens are concerned. I'll stick with inj l-carnitine which is perfectly legal, safe, and tremendously effective for cell volumization, endurance, and performance (the list goes on).
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read my post above yours. caffeine has the same carcinogenic warnings.
 
Gutterpump said:
I'm confused. Caffeine produces nitrosamines?
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same level of warnings:

Caffeine:

CARCINOGENIC EFFECTS: 3 (Not classifiable for human.) by IARC. MUTAGENIC EFFECTS: Mutagenic for mammalian
somatic cells. Mutagenic for bacteria and/or yeast. TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY:
Not available. The substance may be toxic to heart, gastrointestinal tract, central nervous system (CNS). Repeated or
prolonged exposure to the substance can produce target organs damage. Repeated exposure to a highly toxic material may
produce general deterioration of health by an accumulation in one or many human organs.
 
You guys should research all the toxic and "carcinogenic" chemicals in a very popular hygiene product called toothpaste.
 
VaughnTrue said:
I agree that people should be skeptical. I think its a supplement users job to be informed about what they ingest.

KN03 is very safe when provided in 600-1200mg doses. I don't think higher doses are needed. As shown above, you'd need >50g to have actute issues. the msds looks scary, but so does caffeines:




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FWIW I was not slighting you and you company/product but rather was eluding to the very point you made.

Let's not forget you can put data (MSDS) in front of someone and they still can be clueless...case in point above.
 
Afi140 said:
Lord help us. I feel like I am on bb.com right now.
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its a huge challenge to protect and defend the integrity of the boards data base/archives. Misinformation is a permanent record that can't be un-disseminated. Ignorance unfortunately seems to self perpetuate.
 
I don't see the same cancer warning for nitrosamines and caffeine at all:

Cancer

In 1956, two British scientists, John Barnes and Peter Magee, reported that dimethylnitrosamine produced liver tumours in rats. Research was undertaken and approximately 90% of nitrosamine compounds were deemed to be carcinogenic.[9]

In the 1970s, there was an increased frequency of liver cancer found in Norwegian farm animals. The farm animals had been fed on herring meal, which was preserved using sodium nitrite. The sodium nitrite had reacted with dimethylamine in the fish and produced dimethylnitrosamine.[9]

Nitrosamines can cause cancers in a wide variety of animal species, a feature that suggests that they may also be carcinogenic in humans. At present, available epidemiological evidence from case-control studies on nitrite and nitrosamine intake supports a positive association with gastric cancer risk. Regarding oesophageal cancer, available evidence supports a positive association between nitrite and nitrosamine intake and gastric cancer (GC), between meat and processed meat intake and gastric cancer (GC) and oesophageal cancer (OC), and between preserved fish, vegetable and smoked food intake and GC, but is not conclusive.[10]

Hydrazines derived from these nitrosamines, e.g. UDMH, are also carcinogenic.
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Woody said:
I'm not antagonizing. Flouride toothpaste is regulated by the FDA, tested by the ADA, and recommended by dentists and health professionals everywhere.

Can the same be said about KNO3?
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So now the FDA cares to protect us?

Other toothpaste ingredients.
Triclosan Found most often in anti-bacterial products, triclosan supplements many toothpaste brands. Unfortunately, the United States Environmental Protection Agency (EPA) classifies triclosan as a pesticide, stating it poses a risk to both human health and the environment. Scientists categorize triclosan as a chlorophenol, which is a type of chemical suspected of causing cancer in humans.

Sodium Lauryl Sulfate Added as a detergent and cleansing agent, sodium laurel sulfate and its cousin sodium laureth sulfate pose a wide range of potential health risks. On its own, sodium laurel sulfate can damage eyes, irritate skin and lead to labored breathing. According to the American College of Toxicology, sodium laurel sulfate may stay within the body for up to five days, accumulating in the heart, liver, lungs and brain. When combined with certain other chemicals, sodium laurel sulfate transforms into nitrosamines, a class of powerful carcinogens that cause the body to absorb harmful nitrates.

Propylene Glycol An active component in antifreeze, propylene glycol acts as a wetting agent and surfactant in toothpaste. The Material Safety Data Sheets for propylene glycol warn that the chemical can be rapidly absorbed through the skin, with prolonged contact leading to brain, liver and kidney abnormalities. The EPA won’t allow its workers to handle propylene glycol without wearing rubber gloves, yet it doesn’t stop the chemical from being used in common health care products.

DEA Consumers find diethanolamine, or DEA, in products that foam, including toothpaste. DEA disrupts hormones and forms cancer-causing nitrates. According to Dr. Samuel Epstein, professor of environmental health at University of Illinois, repeated skin exposure to DEA can lead to increased risk of liver and kidney cancers.
 
VaughnTrue said:
we were discussing MSDS sheets...



i feel like I'm continually being trolled right now.
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Trolled? No not at all. I'm not arguing either. Everyone is free to take anything they want no matter the risks. I personally just don't see what's so great with this product that it's worth the risks, when there are so many other products / compounds out there with far less risk and far more reward. This is the truth, it's not trolling whatsoever.
 
If Potassium Nitrate is so safe, why would people in this thread who are touting it be taking things to counter act the 'possibility of carcinogenic bypoducts'. No logic to this. It's safe, forget the vitamin C, right?

Does anyone here take anything with their coffee or toothpaste to counter act carcinogenesis? Um no, so why compare them... I really don't see anyone's logic in this thread, but carry on and supplement however you see fit for yourself.
 
Gutterpump said:
If Potassium Nitrate is so safe, why would people in this thread who are touting it be taking things to counter act the 'possibility of carcinogenic bypoducts'. No logic to this. It's safe, forget the vitamin C, right?

Does anyone here take anything with their coffee or toothpaste to counter act carcinogenesis? Um no, so why compare them... I really don't see anyone's logic in this thread, but carry on and supplement however you see fit for yourself.
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The reason you stack vitamin c with potassium nitrate is to prevent nitrate tolerance, not for general health care or "anti-carcinogenic" effects.
 
VaughnTrue said:
The reason you stack vitamin c with potassium nitrate is to prevent nitrate tolerance, not for general health care or "anti-carcinogenic" effects.
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I see, I misread David's post as to why he was taking it. I still don't see logic in using this particular supplement but hey it's none of my business if people take it. My only contribution to this thread is that injectable carnitine will do much more pre-workout, and to a higher degree of efficacy and safety. I really don't have anything else to contribute here and am really not trying to troll.
 
Please read - prevent nitrosamines formation...
mr.cooper69 said:
I recommend vitamin C to prevent nitrosamine formation. The NAC recommendation is for a different reason: it potentiates the activity of nitrates. And like quadzilla linked, it is an ergogen independent of this effect. Vitamin C and NAC are both fine periworkout. The dose makes the poison. Stick to ~250mg vitamin C and 500mg NAC or less

http://anabolicminds.com/forum/supplements/247935-nitrates-cancer.html#post4448136
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Re:

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Also, there are dozens of nitrate containing pre workout supplements on the market. They all have a nitrate that converts to nitrosamines. This is not exclusive to KNO3 nor is potassium more of a contributor to nitrosamines formation. They all do.
 
Ahh I see, I was wondering what VaughnTrue had meant, but it appears I read you correctly.

Yup I know about the pre-workouts that contain them, I've stayed away from all of those supplements. Tried them in my first few years of lifting, but honestly they don't do much for me compared to other things.

Same with arginine and agmatine containing supplements. I haven't really noticed much from them. Agmatine on paper does sound pretty great though.
 
Gutterpump said:
Ahh I see, I was wondering what VaughnTrue had meant, but it appears I read you correctly.

Yup I know about the pre-workouts that contain them, I've stayed away from all of those supplements. Tried them in my first few years of lifting, but honestly they don't do much for me compared to other things.

Same with arginine and agmatine containing supplements. I haven't really noticed much from them. Agmatine on paper does sound pretty great though.
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Research studies on citrulline and nitrates are pretty conclusive (pubmed keywords beet juice and nitrates) on their performance efficacy and anecdotally I do experience all the proported benefits.

Many here report the same and as the market is over saturated with these formulas, ironically I've home brewed long before mainstream retail availability, there evidently must be others experiencing the same.
 
VaughnTrue said:
The reason you stack vitamin c with potassium nitrate is to prevent nitrate tolerance, not for general health care or "anti-carcinogenic" effects.
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You wouldn’t happen to know if I was adding Potassium Nitrate to my Pre the optimum amount of nitrate studied or shown to increase performance and how much vitamin C would you use with that?

Many thanks
 
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