I would like to know what, if any benefits there are to stacking OEP and Recreate (OEP AM dose of 2 and Recreate PM dose of 2)?....
There are significant benefits in stacking Recreate and OEP. A low-stim product, Recreate was designed to target fat loss from a broad variety of pathways that include, but are not limited to, recruiting the sympathomimetic action of the most potent endogenous fat-burning agent, norepinephrine; provoking the selective inhibition of 11-beta-HSD1 for cortisol modulation and reduction in visceral adipose-tissue levels; enhanced stimulation of thyroid function via increased T4 production and increased conversion of T4 to the metabolically more active T3; cAMP activation and the associated metabolic effects (see my earlier post regarding forskolin-induced cAMP activation); and inhibition of the enzyme, glycerol-3-phosphate dehydrogenase that modulates the conversion of glucose into fatty acids; leptin/CCK/GLP1-related appetite regulation [leptin is a hormone that signals the brain to induce satiety. Beyond this, leptin also supports fat breakdown in adipose cells. Futhermore, two of the body's hunger-suppressing hormones are cholecystokinin (CCK) and glucagon-like peptide-1 (GLP-1). These satiety hormones signal the brain that fullness has been reached, and that further caloric intake should cease. In any case, besides fat storage, adipocytes are known to possess active endocrine function. The increase in adipocyte size characterizes increased body-fat mass. This increase in adipocyte size is governed by gene transciption factors (GTFs). In turn, these GTFs modulate the endocrine hormone, adiponectin. Adiponectin expression not only plays a role in adipocyte size increase, but is also involved in insulin sensitivity. Large fat cells show lower adiponectin secretion. Increasing adiponectin levels is important for fat loss and enhanced insulin sensitivity. Recreate supports these benefits]; as well as powerful antioxidant and immune support. So, Recreate is an effective comprehensive low-stim fat-burner that can be used stand-alone or stacked with other stim-based or non-stim far burners.
Now, OEP was specifically designed as an extremely potent stim-based fat burner that is targeted at both generalized and localized annihilation of excess adipose tissue, based on a tight selection of ingredients with both unique and synergistic thermogenic and lipolytic pathways. In particular, OEP activates the so-called mitochondrial uncoupling protein - 1 (UCP-1), a protein that enhances mitochondrial cellular metabolism by directly stimulating the breakdown of stored fatty acids for the generation of energy. This action of fat breakdown and thermogenesis is exerted without stimulating the central nervous system, and occurs in the absence of exercise. So, by recruiting UCP-1, and increasing the resting metabolic rate, OEP supports thermogenesis and lipolysis. Related to this, OEP also supports elevated metabolic action via enhancing thyroid-hormone output [higher T4 and elevated T4-to-T3 conversion] for unprecedented fat loss. Further fat loss is ensured by inhibition of alpha2-adrenoceptor activity [the alpha2 receptor amply located in adipocytes is not only cAMP-inhibiting, but also strongly antilipolytic]; activation of beta-adrenergic receptors [especially beta3 adrenoceptors] that not only activate cAMP, but also induce significant lipolysis. [Please see my earlier post on the implication of cAMP activation for lipolysis and anti-catabolism]. Combine all these with OEP's induction of fat-loss via powerful targeting of subcutaneous fat deposits, and you have a highly specialized product with an unmatched efficacy for localized and generalized elimination of excess fat deposits.
All in all, Recreate and OEP can be used independently of each other for superior fat-burning, but nevertheless will make an extremely effective and synergistic fat-loss stack. **