ostarine bridge between cycle

bfriedman1017

Member
Will ostarine shut me down. I was planning on running 25Mg for 4 to 8 Weeks. But I really don't wanna be shut down and need to wait longer for next cycle. If I stack hcgenerate or something else with the ostarine would that help
 
whats the reason why you want to do ostarine? just curious cause i've tried it before but i found it only good as a recomp/cutting cycle. i didnt get any good aggression, strength, or size off of it.
 
I think ostarine is significantly less suppressive than AAS's, but still suppressive (particularly at 25 mg+ dosage).

If this is true, then the good news is that your HTPA axis should theoretically recover some while on Osta (again, at a reasonable dose) after an AAS cycle. The bad news is that a PCT after the ostarine will be necessary to ensure your boys are fully back online. However, this PCT could be something like half that of a usual PCT, if indeed your HPTA has bounced back some on cycle. I think that fully replacing a PCT with a SARM is not a good idea for the long term health of your body hormonally.

Im still reading what there is out there on SARMs, I am by no means an expert on them so the above is just my understanding as of now.
 
Any way the rest of us can get a gander at these bloods?

ManBeast
 
I wouldn't be afraid to run 12mg for a month of Ostarine. That's pretty much what I do in PCT and have no signs that it hinders recovery.

I also wouldn't run the higher doses of 25mg without following up with a mild PCT afterwards. If you are afraid of shutdown, just run the lower dose and call it good. 12mg is still very nice :sgrin:
 
ManBeast said:
Any way the rest of us can get a gander at these bloods?

ManBeast
Click to expand...
Sure. If I recall correctly, it's frowned upon to link to other forums, so I'll copy and paste.

On the 7th of Feb I started taking Ostarine staring at 5 mg per day and going up to 10 mg. Before I started I had a full baseline blood test on the 4th of Feb (see below), this test flagged little to be concerned about. The cholesterol level was a little elevated and I started taking Benecol (daily drink) to help bring the numbers back to the “normal” range this.
I have experienced the following side effects from the drug:

First couple of days: Slight head ache, possibly a slight increase in libido.
Ongoing:
Lethargy (this is the biggest issue though it does not affect workouts)
Sleep disturbance, mainly due to what appears to be an increased body temperature.
Thirst
Increased appetite
Slight acid reflux (this was experienced last night). I have only had this happen one other time when taking anti malarial drugs (unfortunate side effect of the drugs).


Blood pressure has been totally normal throughout.

As you can see below, the second blood work dated 14th Feb shows, fewer issues (see with*) after taking the drug than before, apart from what appears to be a significant drop in total Testosterone levels. This is something I had not expected as the drug is meant to have little or no suppression.
I would be interested in getting opinions on this.
Could this change from 15.9 nmol/L to 9.6 nmol/L be a normal daily fluctuation in Testosterone level? It does seem to be quite a large 1/3 fluctuation.
If this is symptoms of suppression, this is quite fast (week) in happening for a drug that is meant to have little or no suppression.

Thanks.

RESULTS Base Line. 4th of Feb 2011


HAEMATOLOGY
HAEMOGLOBIN 15.0 g/dL 13.0 - 17.0
HCT 0.442 0.37 - 0.50
RED CELL COUNT 5.08 x10^12/L 4.40 - 5.80
MCV 87.0 fL 80 - 99
MCH 29.5 pg 26.0 - 33.5
MCHC 33.9 g/dL 30 - 35
RDW 13.9 11.5 - 15.0
PLATELET COUNT 209 x10^9/L 150 - 400
MPV 11.3 fL 7 - 13
WHITE CELL COUNT 5.67 x10^9/L 3.0 - 10.0
Neutrophils 2.46 x10^9/L 2.0 - 7.5
Lymphocytes 2.31 x10^9/L 1.2 - 3.65
Monocytes 0.51 x10^9/L 0.2 - 1.0
Eosinophils 0.37 x10^9/L 0.0 - 0.4
Basophils 0.02 x10^9/L 0.0 - 0.1
All cell populations appear normal.
ESR 6 mm/hr 1 - 10
BIOCHEMISTRY
SODIUM 144 mmol/L 135 - 145
POTASSIUM 4.0 mmol/L 3.5 - 5.1
CHLORIDE 104 mmol/L 98 - 107
BICARBONATE 27 mmol/l 22 - 29
UREA 6.2 mmol/L 1.7 - 8.3
CREATININE 80 umol/L 66 - 112
BILIRUBIN 15 umol/L 0 - 20
ALKALINE PHOSPHATASE *38 IU/L 40 - 129
ASPARTATE TRANSFERASE 18 IU/L 0 - 37
ALANINE TRANSFERASE 21 IU/L 10 - 50
LDH 270 IU/L 240 - 480
CK 93 IU/L 38 - 204
GAMMA GT 27 IU/L 10 - 71
Please note new reference range effective 22/09/09
TOTAL PROTEIN 71 g/L 63 - 83
ALBUMIN *51 g/L 34 - 50
GLOBULIN 20 g/L 19 - 35
CALCIUM 2.39 mmol/L 2.15 - 2.55
Corrected Calcium 2.24 mmol/L 2.15 - 2.55
PHOSPHATE 1.28 mmol/L 0.87 - 1.45
URIC ACID 344 umol/L 266 - 474
FASTING BLOOD GLUCOSE 4.7 mmol/L 3.9 - 5.8
FASTING TRIGLYCERIDES 0.9 mmol/L < 2.3
FASTING CHOLESTEROL *5.6 mmol/L Optimum <5.0
HDL CHOLESTEROL *1.7 mmol/L 0.9 - 1.5
HDL % of total 30 % 20 and over
LDL CHOLESTEROL *3.5 mmol/L Up to 3.0
IRON 19.0 umol/L 10.6 - 28.3
T.I.B.C 59 umol/L 41 - 77
TRANSFERRIN SATURATION 32 % 20 - 55
ENDOCRINOLOGY
TESTOSTERONE 15.9 nmol/L 7.6 - 31.4
Reference Ranges apply to adults
Method changed to testosterone II
effective 26.01.10



RESULTS after 7 days, 10 mg Ostarine (MK-2866) per day. 14th Feb 2011.


HAEMATOLOGY
HAEMOGLOBIN 15.5 g/dL 13.0 - 17.0
HCT 0.448 0.37 - 0.50
RED CELL COUNT 5.07 x10^12/L 4.40 - 5.80
MCV 88.4 fL 80 - 99
MCH 30.6 pg 26.0 - 33.5
MCHC 34.6 g/dL 30 - 35
RDW 14.2 11.5 - 15.0
PLATELET COUNT 212 x10^9/L 150 - 400
MPV 11.0 fL 7 - 13
WHITE CELL COUNT 5.73 x10^9/L 3.0 - 10.0
Neutrophils 3.06 x10^9/L 2.0 - 7.5
Lymphocytes 1.81 x10^9/L 1.2 - 3.65
Monocytes 0.56 x10^9/L 0.2 - 1.0
Eosinophils 0.28 x10^9/L 0.0 - 0.4
Basophils 0.02 x10^9/L 0.0 - 0.1
All cell populations appear normal.
ESR 7 mm/hr 1 - 10
This is an amended report and replaces the
previous report issued under the same laboratory
number. Date:14/02/11
BIOCHEMISTRY
SODIUM 143 mmol/L 135 - 145
POTASSIUM 4.8 mmol/L 3.5 - 5.1
CHLORIDE 104 mmol/L 98 - 107
BICARBONATE 28 mmol/l 22 - 29
UREA 5.9 mmol/L 1.7 - 8.3
CREATININE 72 umol/L 66 - 112
estimated GFR >90

BILIRUBIN 9 umol/L 0 - 20
ALKALINE PHOSPHATASE *32 IU/L 40 - 129
ASPARTATE TRANSFERASE 22 IU/L 0 - 37
ALANINE TRANSFERASE 47 IU/L 10 - 50
LDH 300 IU/L 240 - 480
CK 170 IU/L 38 - 204
GAMMA GT 34 IU/L 10 - 71
Please note new reference range effective 22/09/09
TOTAL PROTEIN 75 g/L 63 - 83
ALBUMIN 50 g/L 34 - 50
GLOBULIN 25 g/L 19 - 35
CALCIUM 2.29 mmol/L 2.15 - 2.55
Corrected Calcium 2.15 mmol/L 2.15 - 2.55
PHOSPHATE 1.20 mmol/L 0.87 - 1.45
URIC ACID 341 umol/L 266 - 474
FASTING BLOOD GLUCOSE 4.2 mmol/L 3.9 - 5.8
FASTING TRIGLYCERIDES 0.7 mmol/L < 2.3
FASTING CHOLESTEROL 4.6 mmol/L Optimum <5.0
HDL CHOLESTEROL 1.4 mmol/L 0.9 - 1.5
HDL % of total 30 % 20 and over
LDL CHOLESTEROL 2.9 mmol/L Up to 3.0
IRON 17.0 umol/L 10.6 - 28.3
T.I.B.C 66 umol/L 41 - 77
TRANSFERRIN SATURATION 26 % 20 - 55
ENDOCRINOLOGY
TESTOSTERONE 9.6 nmol/L 7.6 - 31.4
Reference Ranges apply to adults
Method changed to testosterone II
effective 26.01.10

Extra info:
Age 35
Weight 60 kg​
Click to expand...
 
Thank you. Did they conclude that this was a normal fluctuation, or actual suppression? Or were there other factors (time of test/fasted etc.) not presented in that post?

ManBeast
 
wow, impressive. seems like a proper pct should be used even at mid dosage if its actual suppression.
 
Ok everyone debates or says OSTA can or cannot cause shutdown, from everything read, which was a lot cause I research the death out of something before I use it, was that everyone reacted different

Some users experienced no shutdown, some a little, some a lot

However, I have yet to see someone not fully recover

For me, pretty sure 0 shutdown, or at least full recovery, I've run it twice, 4 weeks and 8 weeks, had bloodwork done each time and my test levels were in my normal range shortly after cycle

Never had bloods done while on though, so those results could be different
 
ManBeast said:
Thank you. Did they conclude that this was a normal fluctuation, or actual suppression? Or were there other factors (time of test/fasted etc.) not presented in that post?

ManBeast
Click to expand...

This was my thought as well. I cannot believe that his test levels changed that much in 7 days from Ostarine at a very low dose....that is extremely unrealistic. You wouldn't even get that from a lot of mild oral steroids.

A more logical explanation is that the test was not conducted in the same conditions/methods as the first which would explain the fluctuation. For me, those tests in this example don't hold much water.

I have seen bloodwork from someone that ran Ostarine at 6 weeks 25mg and it did cause suppression and dropped test levels, but not nearly as much as people would think. If I remember right his test levels started around 750 and after his Ostarine run ended between 550-600....still in normal range
 
ManBeast said:
Thank you. Did they conclude that this was a normal fluctuation, or actual suppression? Or were there other factors (time of test/fasted etc.) not presented in that post?

ManBeast
Click to expand...
They didn't really reach any conclusions. The post didn't get many replies, and most of those who replied had no knowledge of Ostarine.
 
you have to understand in this situation that everyone reacts differently to everything... so to gauge if you will get shutdown or not is impossible... GENERALLY, there is a chance of small suppression but as pointed out, NOTHING like an AAS cycle... You need a mini pct, no serm is necessary... I would say unleashed and hcgen or bridge would be sufficient, possibly throw in some daa... your recovery time is much much quicker with sarms as well... 3-4 weeks should be good... NOW, everyone is different... I did 25 mg per day in pct with no issue at all, but what Rick recommended is great as well... You do not want to exceed 25 mg... Thats the sweetspot, anything over will only be a hinderance to you... Keep it smart and you will be really happy with it...
 
Ok a BIG issue here is this... who knows what they are REALLY putting into their body. There are so many ostarine sources..some good...some bad. I am sure half of them at least have contamination and a lot of them are prob spiked with steroids. This bloodwork and all the rest of it is kind of like taking an unlabeled bottle from a cabinet drinking it and then taking a blood test.. you dont know what you are taking. The ostarine suppression story will go on and on but the only real way I will convince myself that it is not suppressive (to me at least) is going to be by buying from a reputable source and then doing my own blood work. I'll prob do this in a few months actually...
 
bigdavid said:
Ok a BIG issue here is this... who knows what they are REALLY putting into their body. There are so many ostarine sources..some good...some bad. I am sure half of them at least have contamination and a lot of them are prob spiked with steroids. This bloodwork and all the rest of it is kind of like taking an unlabeled bottle from a cabinet drinking it and then taking a blood test.. you dont know what you are taking. The ostarine suppression story will go on and on but the only real way I will convince myself that it is not suppressive (to me at least) is going to be by buying from a reputable source and then doing my own blood work. I'll prob do this in a few months actually...
Click to expand...

Be sure to let me know how it goes man!!
 
mattrag said:
Be sure to let me know how it goes man!!
Click to expand...

For sure Ill prob do it with the LMG version when it comes out... but also I might run a test booster along side it so that might even be enough to counteract any suppression...who knows lol
 
bigdavid said:
For sure Ill prob do it with the LMG version when it comes out... but also I might run a test booster along side it so that might even be enough to counteract any suppression...who knows lol
Click to expand...

You mean IML? Iron mag labs. ?
Hehe. I donno if running it along side is beneficial but running it after helps. I'm not sure of the amount of suppression. Some say once you use anything that causes any suppression taking any natty test product is worthless. But then again recently people have been doing so and having better results so who knows lol.
 
mattrag said:
You mean IML? Iron mag labs. ?
Hehe. I donno if running it along side is beneficial but running it after helps. I'm not sure of the amount of suppression. Some say once you use anything that causes any suppression taking any natty test product is worthless. But then again recently people have been doing so and having better results so who knows lol.
Click to expand...

LOL idk why i wrote LMG.. yeah IML woops. Idk im prob gona get in the habit of getting some bloodwork every 6 weeks or so just to make sure my levels are optimal
 
They were just discussing in the posts above yours that it is unknown if stacking those would help.

ManBeast
 
So lets see your real proof that ostarine is a joke, not just some flippant comment without any proof.

ManBeast
 
ostarine is such a joke... it has made it through phase 2 trials and now on phase 3 but its full of crap... right.
 
Well, I would just use anavar instead of ostarine. At a dose to compare and really beat ostarine it is more cost effective and has real studies behind it along with real world uses for burn/aids patients.
 
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