Ostar1ne

Kickstart7 said:
all I'll be using is EP1C honestly! Today was my last day of DAA and nolva. I have finaflex pct revolution at home but idk if I need to use an AI. It's obviously has other things in it but I don't think I need an AI and I don't want my libido to go down.
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forgive me for my grammatical errors btw, in a rush lol.
 
Ostabol has this on the bottle and it's one of the most trusted.
 
Mystere3 said:
Ostarine doesn't convert to e2. It can increase free e2 a bit due to it's effects on shbg but it doesn't aromatize. It's not a steroid so it's not possible for it to aromatize.
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Mystere3 I knew there was a rise in E2 in some way or another and just thought it may be converting. Do you happen to know how it frees up E2? So hard to keep track of all the research we do with everything that keeps coming out.
goodvibes said:
I always have AIs, test boosters & friends with serm on hand :)
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Good stuff!
uubiduu said:
isnt there a warning notice on the bottle "only for research purposes"?Then its even more likely to be spiked
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I am not sure what gave you that idea. Almost ever research chemical you get will have for research purposes only on it. This allows it to be sold legally as not being intended for human use. What you do with it once in your possession, IE consumption it is your responsibility.

That being said I am not sure if you have to put that on Osta bottles from a supplement company or not; or if that is just carry over from before it was being sold as a supplement.
 
So any compound that binds the androgen receptor will exert negative feedback. The result of that feedback affects multiple systems. The most obvious effect is that total test will decrease slightly, as may lh and fsh depending on the dose. The other is that shbg will be decreased. That will increase the amount of free test relative to total test, such that your overall free test will likely not be affected, depending on dosing. However, a side effect of decreasing shbg is that your free estrogen will increase because it's not bound by shbg. Therefore, while ostarine won't aromatize or increase total e2, it will increase free e2.

Gtx wrote this in their abstract about ostarine when it was initially published: "In men, no statistically significant differences from placebo in change from baseline values for free testosterone, DHT, estradiol, follicle-stimulating hormone (FSH), or LH were observed at any GTx-024 dose. However, sex hormone-binding globulin (SHBG) was significantly reduced with GTx-024 3 mg versus placebo. The decrease in SHBG was accompanied by a reduction of serum total testosterone in subjects treated with 1 mg or 3 mg of GTx-024 compared to placebo. This data demonstrates that Ostarine is total testosterone suppressive but free testosterone, LH and FSH were not statistically suppressed."
 
Mystere3 said:
So any compound that binds the androgen receptor will exert negative feedback. The result of that feedback affects multiple systems. The most obvious effect is that total test will decrease slightly, as may lh and fsh depending on the dose. The other is that shbg will be decreased. That will increase the amount of free test relative to total test, such that your overall free test will likely not be affected, depending on dosing. However, a side effect of decreasing shbg is that your free estrogen will increase because it's not bound by shbg. Therefore, while ostarine won't aromatize or increase total e2, it will increase free e2.

Gtx wrote this in their abstract about ostarine when it was initially published: "In men, no statistically significant differences from placebo in change from baseline values for free testosterone, DHT, estradiol, follicle-stimulating hormone (FSH), or LH were observed at any GTx-024 dose. However, sex hormone-binding globulin (SHBG) was significantly reduced with GTx-024 3 mg versus placebo. The decrease in SHBG was accompanied by a reduction of serum total testosterone in subjects treated with 1 mg or 3 mg of GTx-024 compared to placebo. This data demonstrates that Ostarine is total testosterone suppressive but free testosterone, LH and FSH were not statistically suppressed."
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Thanks and great info! Repped!

Anyone reading this and getting something out of it should rep this man!
 
Mystere3 said:
So any compound that binds the androgen receptor will exert negative feedback. The result of that feedback affects multiple systems. The most obvious effect is that total test will decrease slightly, as may lh and fsh depending on the dose. The other is that shbg will be decreased. That will increase the amount of free test relative to total test, such that your overall free test will likely not be affected, depending on dosing. However, a side effect of decreasing shbg is that your free estrogen will increase because it's not bound by shbg. Therefore, while ostarine won't aromatize or increase total e2, it will increase free e2.

Gtx wrote this in their abstract about ostarine when it was initially published: "In men, no statistically significant differences from placebo in change from baseline values for free testosterone, DHT, estradiol, follicle-stimulating hormone (FSH), or LH were observed at any GTx-024 dose. However, sex hormone-binding globulin (SHBG) was significantly reduced with GTx-024 3 mg versus placebo. The decrease in SHBG was accompanied by a reduction of serum total testosterone in subjects treated with 1 mg or 3 mg of GTx-024 compared to placebo. This data demonstrates that Ostarine is total testosterone suppressive but free testosterone, LH and FSH were not statistically suppressed."
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Planning an ostabol cycle - great post! Rep'd!
 
Great thread. Wish I would have known some of these tidbits prior to my run of Ostabol. Had nice recomp effects, but it murdered my libido to the point of not even having a sexual thought for days at a time. A little AI probably would have prevented that.
 
40 mg osta is way too much. 20-25 mg is about where you see max effect. You take more and get sides, but without any additional benefit.
 
bioman said:
Great thread. Wish I would have known some of these tidbits prior to my run of Ostabol. Had nice recomp effects, but it murdered my libido to the point of not even having a sexual thought for days at a time. A little AI probably would have prevented that.
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Running some ostabol in September. Any more info on your run? Dosing, gains, other pertinent info etc?
 
20mg/day in two doses. I was recomping and Ostabol seemed to really help in the department. Dropped some bf, had greater muscle fullness, decent endurance boost and mood. Got the flu in the middle of the run, so it kinda derailed things, but this is what I noticed.
 
Getting ostarine(brawn o-bol) and 11-andro in a few days. Any point stacking? Like 10-20mg o bol and 300mg 11 andro?
Or starting with one and run overlap/stack halfway through, plus adding erase pro at the end?
 
I'm thinking I'll run ostabol 6 wks at 20 mg with some dermacrine tagged on those last 4 weeks. Seems like a solid little run....
 
woodbear said:
Getting ostarine(brawn o-bol) and 11-andro in a few days. Any point stacking? Like 10-20mg o bol and 300mg 11 andro?
Or starting with one and run overlap/stack halfway through, plus adding erase pro at the end?
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I am currently running the same stack, started 3 days ago on 300 mg 11-andro + 10 mg Osta (will bump up to 20 mg in week 4-5). Currently on a cutting diet, according to the guys I bought it from this should be a great stack. Will keep you posted.

Good luck with your cycle :)
 
Thanks for the info. I never take the liver hard stuff anymore, actually this is the first stuff i m trying in a good while. Since i have been waiting for this not so harsh stuff for a while. Always found that the cons outweight the pros with the harder stuff. Also a few barbeque parties are still on schedule this summer, and i want to have a beer or three:-) Ostarine and 11 - andro should be fairly non toxic , but i will not binge drink the gains away:-) That said, i might do them each more or less solo , and it is slow bulk time, hopefully leaner with this. I.ll post results/during, but no logging
 
Just broke down and purchased Ostarine ahead of their blockbuster saile on NP....the reviews and such were just too, too positive for me to wait until August 5th.

Should have this in my hand by Wednesday. Can't wait to try it.
 
Hearf good things too, not extreme, but clean and pct less unlesyou go overboard on the dose
I think a 10-20 mg dose for 6-8 weeks is better for lasting gains than 3 weeks of waterbloating...
 
woodbear said:
Hearf good things too, not extreme, but clean and pct less unlesyou go overboard on the dose
I think a 10-20 mg dose for 6-8 weeks is better for lasting gains than 3 weeks of waterbloating...
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Yeah, majority of the users who reviewed it, used between 15-20mg daily. I'm near 225lbs, so I'm going to use 20mg for 8 weeks.
 
Hercules1982 said:
I am currently running the same stack, started 3 days ago on 300 mg 11-andro + 10 mg Osta (will bump up to 20 mg in week 4-5). Currently on a cutting diet, according to the guys I bought it from this should be a great stack. Will keep you posted.

Good luck with your cycle :)
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same here! I'm on week 6 now at 25mg Osta ed and 300mg 11-Andro ed and I'm very glad with the results! Deep cuts and lots of vascularity
Haven't got ill or something. Just got sometimes high BP. But only on some days.
will go another 4-6 weeks and finish with erasepro + daa.
recommend it to you, guys :bigok:

edit: libido sky high 24/7 + no problems with gyno
 
Nice! Im on day 2, nothing to report other than i dont need a pwo for hard pumps!
Splitting dose 2x10mg, but switching to 20 mg in the morning, read that osta has a 24 hour halflife, so splitting is no point
 
woodbear said:
Nice! Im on day 2, nothing to report other than i dont need a pwo for hard pumps!
Splitting dose 2x10mg, but switching to 20 mg in the morning, read that osta has a 24 hour halflife, so splitting is no point
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I got an insane pump on day 3, as well as several PBs, DEEP into a cut.
This thing is awesome, will publish a log later.
 
woodbear said:
Nice! Im on day 2, nothing to report other than i dont need a pwo for hard pumps!
Splitting dose 2x10mg, but switching to 20 mg in the morning, read that osta has a 24 hour halflife, so splitting is no point
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Yeah, I was going to follow the same protocol, but I too, also heard that it has a 24 hour half life.
 
I'm currently logging Ostar1ne, and I have been ramping up my dose, which has worked quite well for me. I started at 10mg (2 caps), and am now up to 20mg (4 caps) every day.

Strength gains seem to be kicking in, and I love the fullness and vascularity. Pump is actually a little ridiculous at times!
 
Misfit28 said:
I'm currently logging Ostar1ne, and I have been ramping up my dose, which has worked quite well for me. I started at 10mg (2 caps), and am now up to 20mg (4 caps) every day.

Strength gains seem to be kicking in, and I love the fullness and vascularity. Pump is actually a little ridiculous at times!
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Cool. So how long have you been using it again? I'm only on day 2. I took my first dose (20mg) yesterday evening and took my 2nd dose this morning and will take every morning from this point.
 
What are you running after your Ostar1ne cycle?

The only thing I am running with osta is Multivitamin (orange triad) protein and creatine.

What else should i pick up for cycle support and pct?
 
Just started Day 14 today. I ran 2 caps for a week, 3 caps for the second week, and now bumping up to 4 caps.

I'm only dosing once a day as well. IMO, no need to dose twice due to the long half-life.

The way I've been dosing it would give 6 weeks at 20mg (4 caps), assuming I taper back down by 1 cap at a time. Anyone have any input about ramping up/down, any solid reasons for/against it?
 
pjunior33 said:
What are you running after your Ostar1ne cycle?

The only thing I am running with osta is Multivitamin (orange triad) protein and creatine.

What else should i pick up for cycle support and pct?
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I'm running it as a PCT for XI-KT, even though XI-KT isn't very suppressive. I'm running OT, Fish oil (Oximega), Cadence, EndoSurge Turbo, MacaPro, AdrenoSurge and Supremacy 2.0 and BodyForge 2.0 with it :D
 
Okay, well I have a little over a week left on XI-KT. Stuff did wonders for me for the first 3 weeks or so then started to even out in regards to results.

But yeah, based on the reviews, 20mg for Osta seems to be the magic spot so I am going to keep it at that level for the next 6 weeks. I may add ep1c on week 3 but haven't decided whether I'm going to do that or not.
 
anabolix said:
40 mg osta is way too much. 20-25 mg is about where you see max effect. You take more and get sides, but without any additional benefit.
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That is a personal opinion and varies per each persons use, I wish people would say "I think" or "in my opinion / experience" instead of stating opinions as if they were fact. It is how so much bro science gets perpetuated.

I definitely noticed an increase in gains at 40 compared to 20. Yes I did need a very mild AI @40 but the difference was easily noticeable and being managed with an OTC AI it was an improvement over the 20 that I considered well worth it. However just my personal experience.

Misfit28 said:
Just started Day 14 today. I ran 2 caps for a week, 3 caps for the second week, and now bumping up to 4 caps.

I'm only dosing once a day as well. IMO, no need to dose twice due to the long half-life.

The way I've been dosing it would give 6 weeks at 20mg (4 caps), assuming I taper back down by 1 cap at a time. Anyone have any input about ramping up/down, any solid reasons for/against it?
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Some people prefer to keep hormones level so even with a 24 hr halflife you are not that close to level there is still a big swing. So if the level thing is important to you then at least 2 doses day would keep highs and lows from being to different. However you are going to make gains either way.

I do not really know of a reason to taper regarding side effects or rebound of any kind.
 
MrKleen73 said:
That is a personal opinion and varies per each persons use, I wish people would say "I think" or "in my opinion / experience" instead of stating opinions as if they were fact. It is how so much bro science gets perpetuated.

I definitely noticed an increase in gains at 40 compared to 20. Yes I did need a very mild AI @40 but the difference was easily noticeable and being managed with an OTC AI it was an improvement over the 20 that I considered well worth it. However just my personal experience.



Some people prefer to keep hormones level so even with a 24 hr halflife you are not that close to level there is still a big swing. So if the level thing is important to you then at least 2 doses day would keep highs and lows from being to different. However you are going to make gains either way.

I do not really know of a reason to taper regarding side effects or rebound of any kind.
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Thanks for sharing. Yeah, I am going to take 20mg in the mornings to see how I respond however, it's good to know that one was able to take over the recommended/suggested 20-25mg limit w/out any adverse side effects.
 
MrKleen73 said:
That is a personal opinion and varies per each persons use, I wish people would say "I think" or "in my opinion / experience" instead of stating opinions as if they were fact. It is how so much bro science gets perpetuated.

I definitely noticed an increase in gains at 40 compared to 20. Yes I did need a very mild AI @40 but the difference was easily noticeable and being managed with an OTC AI it was an improvement over the 20 that I considered well worth it. However just my personal experience.



Some people prefer to keep hormones level so even with a 24 hr halflife you are not that close to level there is still a big swing. So if the level thing is important to you then at least 2 doses day would keep highs and lows from being to different. However you are going to make gains either way.

I do not really know of a reason to taper regarding side effects or rebound of any kind.
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That makes sense. I'll try splitting my 4 caps into 2/2 and see if i notice anything.

Thanks!
 
anabolix said:
40 mg osta is way too much. 20-25 mg is about where you see max effect. You take more and get sides, but without any additional benefit.
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cbsharpe said:
Thanks for sharing. Yeah, I am going to take 20mg in the mornings to see how I respond however, it's good to know that one was able to take over the recommended/suggested 20-25mg limit w/out any adverse side effects.
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You will enjoy it at 20mgs. When i ran it I had already run several designers so 20mgs was simply not living up to my expectations after 4 weeks. I bumped to 40 and noticed differences in recovery almost immediately.
Misfit28 said:
That makes sense. I'll try splitting my 4 caps into 2/2 and see if i notice anything.

Thanks!
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Yeah I have done both not really sure there was a difference to be honest BUT if you are a person that feels more comfortable with remaining level then it is a good suggestion for peace of mind if nothing else.
 
Misfit28 said:
I'm running it as a PCT for XI-KT, even though XI-KT isn't very suppressive. I'm running OT, Fish oil (Oximega), Cadence, EndoSurge Turbo, MacaPro, AdrenoSurge and Supremacy 2.0 and BodyForge 2.0 with it :D
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you're running ostarine as a pct?
 
Mystere3 said:
you're running ostarine as a pct?
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Not as my sole PCT, no.

Did you read the other things that I am taking? Two natty test boosters, anti-cortisol/stress support and libido support.

XI-KT isn't that suppressive, and the Ostar1ne at 20 mg for a few weeks won't be either.
 
Misfit28 said:
Not as my sole PCT, no.

Did you read the other things that I am taking? Two natty test boosters, anti-cortisol/stress support and libido support.

XI-KT isn't that suppressive, and the Ostar1ne at 20 mg for a few weeks won't be either.
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Exactly!
 
OSTA Up to 30 today! WHAT!
 
It's only useful in PCT from a real steroid to maintain gains; in that setting I'd just call it supplementation. It's a stronger agonist of the androgen receptor than 11-KT is by far.

Misfit28 said:
Not as my sole PCT, no.

Did you read the other things that I am taking? Two natty test boosters, anti-cortisol/stress support and libido support.

XI-KT isn't that suppressive, and the Ostar1ne at 20 mg for a few weeks won't be either.
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one week. Maybe gained a pound or two... no sides, slightly more full feeling , good pumps and better recovery(and libido is up )
Also, I did a stupid thing a few months ago training shoulders heavy with smith machine shoulder presses, and after a while, after no shoulder pain for years, my nagging shoulder came back. It seems to have gotten very much better this week, almost gone!
 
woodbear said:
one week. Maybe gained a pound or two... no sides, slightly more full feeling , good pumps and better recovery(and libido is up )
Also, I did a stupid thing a few months ago training shoulders heavy with smith machine shoulder presses, and after a while, after no shoulder pain for years, my nagging shoulder came back. It seems to have gotten very much better this week, almost gone!
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Yea man after 12-14 days it will be completely in your system too just wait it gets better
 
MrKleen73 said:
You will enjoy it at 20mgs. When i ran it I had already run several designers so 20mgs was simply not living up to my expectations after 4 weeks. I bumped to 40 and noticed differences in recovery almost immediately.

Yeah I have done both not really sure there was a difference to be honest BUT if you are a person that feels more comfortable with remaining level then it is a good suggestion for peace of mind if nothing else.
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Yea I've always run an AI with ostarine and realize there's no need for it at all. Next time I run it solo I won't use an AI. Tempted to use it now since I'm having tendonitis flares. I know this shyt heals injuries it did for me in the past! Lol
 
I`m wondering if there is any point to add 11-andro to this cycle, or perhaps run it solo later. Supposed to add 300mgs of that daily in 6-7 days..
Still using Ostarine 20mg all in the morning. Might start splitting when (if) I add 11-andro
 
If I have a full PCT ready, and am trying to lose as much BF as possible with Formeron/XI-KT, is there any reason why I shouldn't run this at 30/day?
 
whyteboi said:
If I have a full PCT ready, and am trying to lose as much BF as possible with Formeron/XI-KT, is there any reason why I shouldn't run this at 30/day?
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So long as you have a good PCT and it aligns with your goals then no there is not any reason.
 
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