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1: Med Sci Sports Exerc. 2007 Jun;39(6):934-40.Click here to read Links
Dietary apple polyphenols enhance gastrocnemius function in Wistar rats.
Nakazato K, Song H, Waga T.
Department of Exercise Physiology, Graduate School of Health and Sport Sciences, Nippon Sport Science University, Tokyo, Japan. [email protected]
PURPOSE: Green tea polyphenols have been reported to improve muscle function in dystrophic mice. The chemical structure of apple polyphenols (APP) is similar to that of tea polyphenols; however, their effects on muscle function have not been examined previously. We examined the effects of dietary intake of APP on gastrocnemius function in Wistar rats. METHODS: Sixteen male rats (11 wk old) were divided into two groups: the 4.8% APP diet group and the control group (N=8 in each group). Before and after 3 wk of treatment, right-leg tetanic ankle torques were measured. Successive twitch torques (four sessions per minute for 2 min) were also measured to test indications of fatigue. Contralateral (left) legs were used for wet weight measurement and examination of mRNA expression. RESULTS: Total-body and muscle weights were similar in both the groups. The adipose tissue weight of the APP group was significantly lower than that of the control group (P<0.05). The isometric torque of the APP group was significantly higher than that of the control group (P<0.05). During the 2-min experimental period, the relative twitch torques (compared with the initial value) of the APP group were larger than those of the control group. Statistical significance was observed at 90, 105, and 120 s (P<0.05). Expression of peroxisome proliferator-activated receptors alpha and delta--positive regulators of lipid oxidation--were significantly higher in the APP group than in the control group (P<0.05). CONCLUSION: We conclude that dietary APP enhance normal muscle function in Wistar rats. Alteration of lipid metabolism might be one of the mechanisms of this phenomenon.
PMID: 17545882 [PubMed - indexed for MEDLINE]
This also lends more credence to our initial hypothesis that a single capsule of NOxidant taken preworkout will enhance muscular contractile force, as well as amplifying the fat burning effects of DCP.
I have been doing this for about 1 1/2 weeks, along with 2 Xtra Strength tums (google calcium and muscle contraction) and noticed a decent increase in strength and rep range.
1: Med Sci Sports Exerc. 2007 Jun;39(6):934-40.Click here to read Links
Dietary apple polyphenols enhance gastrocnemius function in Wistar rats.
Nakazato K, Song H, Waga T.
Department of Exercise Physiology, Graduate School of Health and Sport Sciences, Nippon Sport Science University, Tokyo, Japan. [email protected]
PURPOSE: Green tea polyphenols have been reported to improve muscle function in dystrophic mice. The chemical structure of apple polyphenols (APP) is similar to that of tea polyphenols; however, their effects on muscle function have not been examined previously. We examined the effects of dietary intake of APP on gastrocnemius function in Wistar rats. METHODS: Sixteen male rats (11 wk old) were divided into two groups: the 4.8% APP diet group and the control group (N=8 in each group). Before and after 3 wk of treatment, right-leg tetanic ankle torques were measured. Successive twitch torques (four sessions per minute for 2 min) were also measured to test indications of fatigue. Contralateral (left) legs were used for wet weight measurement and examination of mRNA expression. RESULTS: Total-body and muscle weights were similar in both the groups. The adipose tissue weight of the APP group was significantly lower than that of the control group (P<0.05). The isometric torque of the APP group was significantly higher than that of the control group (P<0.05). During the 2-min experimental period, the relative twitch torques (compared with the initial value) of the APP group were larger than those of the control group. Statistical significance was observed at 90, 105, and 120 s (P<0.05). Expression of peroxisome proliferator-activated receptors alpha and delta--positive regulators of lipid oxidation--were significantly higher in the APP group than in the control group (P<0.05). CONCLUSION: We conclude that dietary APP enhance normal muscle function in Wistar rats. Alteration of lipid metabolism might be one of the mechanisms of this phenomenon.
PMID: 17545882 [PubMed - indexed for MEDLINE]
This also lends more credence to our initial hypothesis that a single capsule of NOxidant taken preworkout will enhance muscular contractile force, as well as amplifying the fat burning effects of DCP.
I have been doing this for about 1 1/2 weeks, along with 2 Xtra Strength tums (google calcium and muscle contraction) and noticed a decent increase in strength and rep range.
. The abstract i posted in the NOxidant write-up goes hand in hand with what matt has posted here. I have yet to test the same theory myself, but i look forward to in the comming month. 