Myostatin Inhibitors??

[Lukef2000]

Does anyone have any experience with these? If so how do you feel it worked for you??

I've been reading a bit lately re why you seem to plateau after 8-10 weeks on gear, from what I've been reading an increase in myostatin could be the culprit.

 

[Grayson]

Don't bother. The only compound would be sulforaphane. I forgot, but I remember reading that you'd have to eat broccoli sprouts in order to receive any benefit.

 

[mountainman33]

Does anyone have any experience with these? If so how do you feel it worked for you??

I've been reading a bit lately re why you seem to plateau after 8-10 weeks on gear, from what I've been reading an increase in myostatin could be the culprit.

Unfortunately there is no real "inhibitor" that I've heard of or am aware of. I've researched the crap out of them and the only thing that you could really potentially get inhibition from is by ingesting brown seaweed extract, but it's been ineffective in human studies. But I guarantee you that when one does come out it'll blow the entire anabolic world away.

 

[Rarchib]

Does anyone have any experience with these? If so how do you feel it worked for you??

I've been reading a bit lately re why you seem to plateau after 8-10 weeks on gear, from what I've been reading an increase in myostatin could be the culprit.

I believe creatine is a myostatin inhibitor

 

[RecompMan]

I believe creatine is a myostatin inhibitor

Slight, very slight.

Melatonin can be considered one as well as ursolic acid

Stat 3 inhibition is one way to go about it.

 

[Grayson]

Slight, very slight.

Melatonin can be considered one as well as ursolic acid

Stat 3 inhibition is one way to go about it.

What's the research on melatonin and at what dose?

 

[RecompMan]

What's the research on melatonin and at what dose?

Ill have to look into it again, but I remember reading about its effect on stat3

I think the doses used was 5mg but ill have to check. Most studies are done at 5mg or under 1mg

 

[RecompMan]

May be it?


http://www.plosone.org/article/info:doi/10.1371/journal.pone.0057941

 

[RecompMan]

Stat3 inhibition and myostatin


http://m.ajpendo.physiology.org/content/303/3/E410.short

 

[RecompMan]

http://onlinelibrary.wiley.com/doi/10.1002/ar.20659/full

 

[Lukef2000]

Don't bother. The only compound would be sulforaphane. I forgot, but I remember reading that you'd have to eat broccoli sprouts in order to receive any benefit.

Sulforaphane? I'll have to look into it, seems you can supplement anythings these days.

Unfortunately there is no real "inhibitor" that I've heard of or am aware of. I've researched the crap out of them and the only thing that you could really potentially get inhibition from is by ingesting brown seaweed extract, but it's been ineffective in human studies. But I guarantee you that when one does come out it'll blow the entire anabolic world away.

That's unfortunate. Brown seaweed extract? I'll have to look into that one. Oh man when an effective one comes out it will change the game!

I believe creatine is a myostatin inhibitor

Cool I already take creatona so let's hope that's helping!

Slight, very slight. Melatonin can be considered one as well as ursolic acid Stat 3 inhibition is one way to go about it.

I take melatonin every night due to sleeping issues so it's good to know there's additional benefits. Uralic acid? I'll have to look into it. I'll have to do a bit of research h about stat3 inhibition! Thanks ebf!

 

[Lukef2000]

Stat3 inhibition and myostatin http://m.ajpendo.physiology.org/content/303/3/E410.short

I'll have to read this a bit later. I think if anyone brings an effective one out they'll make a ****load of money lol.

 

[jbryand101b]

Does anyone have any experience with these? If so how do you feel it worked for you??

I've been reading a bit lately re why you seem to plateau after 8-10 weeks on gear, from what I've been reading an increase in myostatin could be the culprit.

What you've been reading is correct. I like ur spray

There was another thread recently about myostatin inhibitors, I posted info on ursolic acid
http://anabolicminds.com/forum/supplements/240263-myostatin-blockers-real.html

 

[Quadzilla99]

Sulforaphane? I'll have to look into it, seems you can supplement anythings these days.

Some good PA posts in here: http://anabolicminds.com/forum/supplement-science/238853-sulforaphane-inhibits-myostatin.html

 

[Lukef2000]

What you've been reading is correct. I like ur spray There was another thread recently about myostatin inhibitors, I posted info on ursolic acid http://anabolicminds.com/forum/supplements/240263-myostatin-blockers-real.html

Thanks for that Jbry. I think I may have to try Ursolic acid with me next run.

Some good PA posts in here: http://anabolicminds.com/forum/supplement-science/238853-sulforaphane-inhibits-myostatin.html

Cheers for that man. Not sure where I would find those over here in aus. Time to start googling lol.

 

[Kevinhim]

Thanks for that Jbry. I think I may have to try Ursolic acid with me next run. Cheers for that man. Not sure where I would find those over here in aus. Time to start googling lol.

For what it's worth, I just finished running pump spray (transdermal Ursolic acid) for about 8 weeks, and I deff had noticeable recomp effects w/ little change to my diet. Strong believer.

 

[jbryand101b]

Pump spray an ur spray are different from my understanding.

 

[JD261985]

What you've been reading is correct. I like ur spray There was another thread recently about myostatin inhibitors, I posted info on ursolic acid http://anabolicminds.com/forum/supplements/240263-myostatin-blockers-real.html

Gonna start UR spray in 2 weeks. Gonna use it for 16. It's definitely a solid product. It has way more ursolic acid than pump spray

 

[ronnielf1]

Okay thanks now how do I edit my profile?

 

[djbombsquad]

Sulforaphane http://www.ncbi.nlm.nih.gov/m/pubmed/21465338/

 

[djbombsquad]

http://www.ncbi.nlm.nih.gov/m/pubmed/23092945/

 

[cobri66]

Didn't do crap...plus side I thought it tasted delicious..