The study of carnitine showed something like 80 grams of simple carbs necessary to increase muscle carnitine content over a period of MONTHS. Not worth it in a number of respects.
HOWEVER, PLCAR directly enters the cell independent of carbohydrate intake. Reference:Wiseman LR, et al. "Propionyl-l-carnitine." Drugs Aging. (1988);12:243-8
I am not certain I would say
Not worth it, as a means to compeltely discount it. If one is to dose Carnitine forms, dosing around ingestion of carbs (assuming one is on a diet involving moderate/high carb intake) would be prudent, even if increase is only marginal. You are taking the carbs anyway, why not correlate dosage? Similar to my quote below, I am not ingesting BCAA/Carbs specifically for the Carnitine, but the combination seems worthwhile since both would be ingested either way.
As for the study, do you have access to the full text? The abstract doesn't provide much in terms of details (besides apparent increase in walking endurance). I ask not as a challenge to the information provided, but as a development of my curiosity towards the pharmacokinetics/dynamics they may have explored in detail.
Don't bother. Let's hypothesize that increasing muscle carnitine does indeed accelerate fat loss. To what extent will it do so? Probably minimally. Just use PLCAR if boosting muscle carnitine is your goal.
Again, it would really come down to the difference in the amount of total carnitine content compared between say, orally dosed PLCAR and injected L-car in combination with low dosed insulin. Larger picture would be at similar dosing, which would show higher levels of muscle free carnitine levels when exercise reaches higher intensity, which
should allow for higher rates of fat oxidation. The extent to which one would be more effective as a means of the implied marginal difference, it would be my assumption that a user who is willing to use insulin would be interested in every possible increase in effectiveness available, irregardless of condition of benefit. Although, if I would easily hypothesize, the latter protocol would result in a significant increase as compared to the former. Remember, alot of the methods I blab about is not a recommendation to any member on the board, nor does it imply using the protocol myself. My interest comes from understanding the highest possible manipulation of the bodies processes to facilitate the change a user is pursuing.
