methylated orals

[chize]

do all methylated orals have the same liver toxicity? or does it depend on the compound/amount taken or other things?

 

[bigpapa]

no depends on the compound. for example...m-drol has a much higher toxicity than say h-drol or epi/havoc. phera compounds can be high also. and the original M1T was even higher in toxicity than superdrol i believe.

 

[nattydisaster]

Big difference...for example M-drol and other superdrol clones are very very harsh on your liver where things like Epistane are not near as hard on it.

 

[chize]

why exactly is it harsher on your liver does anyone know?

 

[bigpapa]

why exactly is it harsher on your liver does anyone know?

out of what compounds? examples?

 

[chize]

oh just why would superdrol be more toxic than say epistane mg to mg?

 

[bigpapa]

because m-drol is a steroid. it is just a very harsh compound all around in general. i think it has to do with where the carbon atoms and methylated structures are in the make up but i am not 100% on that

 

[Space]

It has to do with the steroids individual affinity for glucuronyl transferase. Glucuronyl transferase converts the steroid to a glucoronide metabolite that's toxic to the liver.

 

[chize]

It has to do with the steroids individual affinity for glucuronyl transferase. Glucuronyl transferase converts the steroid to a glucoronide metabolite that's toxic to the liver.

thanks!! thats the answer i was looking for