Hard to say, I think both HCG and Arimidex are safe when used in doses mostly used for TRT.
Human Growth Hormone, HGH,
I have cancer, liposarcoma.
Some cancers are promoted by HGH, my cancer is within that group, I will not use HGH.
All this is rather cutting edge, hard to find definitive information.
Lately there was a thread on Sermorelin.
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Sermorelin induces body to produce its own HGH.
It is going to be tougher and tougher to figure out.
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With your TotalT=425 you have little choice, you have to use testosterone.
You do have certain amount of choice about HCG.
If you do not care about preserwing fertility, do not use HCG, your testis will shrink but that is cosmetics at this point.
Make sure that you get more thorough test than just testosterone, usually people who have low T shortly find out about other problems that they have.
Start with good blood test. Use mine list here, post #44.
You may want to peruse the whole thread.
http://anabolicminds.com/forum/male-anti-aging/66268-jans-bloodtest-april13-2.html
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Often people start on Tgels, creams etc. Transdermals do not work for certain group of people. For some they work.
Try to spend as liitle time as possible on transdermals.
If you find they do not work for you go ASAP for injections.
Make sure they are SubQ 31ga needles, rather than big nails.
Here usualy doc may want to give you only smal dose of Testosterone, no HCG and se if that would work.
After your testis are shrunk, they make attempt at reviwing them, give you script for HCG.
I wish I could have started with higher dose of T and HCG righ away.
On my thread:
http://anabolicminds.com/forum/male-anti-aging/66268-jans-bloodtest-april13-2.html
I figured out how to get to proper injected T-dose quicker.
You need to have SHBG value to figure that out.
When time comes I can help you figure out your initial dose.
Make sure you do long blood test, will save you tons of grief.