Info on AIs

CatSnake

Well-known member
Awards
1
  • Established

CatSnake

Well-known member
Awards
1
  • Established
Femara (letrozole)

2.5 mg/wk decreased estradiol from 123 to 57 and increased testosterone from 5.9 to 19.6, LH from 4.4 to 11.1 and FSH from 4.8 to 12.1 in 6 weeks:

http://www.eje-online.org/content/158/5/741.full.pdf

5 mg/wk decreased estradiol by 53 pmol, increased testosterone 12.8 nmol, and decreased 7 kg/bodyweight in 6 months:

http://www.endocrine-abstracts.org/ea/0020/ea0020p444.htm

http://www.fertstert.org/article/S0015-0282(10)02582-3/fulltext

http://www.eje.org/content/160/3/397.full


^however, letro is notorious for crashing E2 levels to undetectable levels, so there's that concern...
 

CatSnake

Well-known member
Awards
1
  • Established
Update:

One thing to add, is that dosing an AI at the same time as an injection might not be a good idea. it takes a while for the cyp/enanthate/prop to get absorbed in the body, and a tad longer before the body recognizes the high testosterone levels and begins aromatization into estrogen/estradiol....

personally, I found taking arimidex when I took an injection to result in low E2 symptoms the next day. however, taking the arimidex 4-12 hours after the injection has completely mitigated that side effect.


"For the 100 mg group, the average Cmax peaked above 1,200 ng/dL 24 hours after the last dose and declined to slightly above 600 ng/dL after 1 week." (testosterone enanthate)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5182226/


Various doses of testosterone, and ensuing E2 levels, etc

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913038/


"Anastrozole was rapidly absorbed orally (time to reach maximum concentration, 1 h) with a slow apparent clearance of 1.54 liters/h and a terminal half-life of 46.8 h."

https://academic.oup.com/jcem/article-abstract/94/8/2975/2597128?redirectedFrom=fulltext





.
 
Thread starter Similar threads Forum Replies Date
justhere4comm Nutrition / Health 0
Anabolics 3
Anabolics 2
Anabolics 2
Anabolics 12

Similar threads


Top