It would actually be best to stack the MCC with CEE .. I've used it in the Green Bulge product (
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I found this article for you as well for MCC:
Creatine Chelated with Magnesium
Magnesium and creatine have been proven to provide beneficial effects in the same diverse areas of physiological activities. Since their biochemical roles are also closely interlaced in very specific reactions, researchers thought it logical to unite magnesium and creatine into a single compound.
The formation of a chelate of creatine with magnesium using patented technology, can protect the creatine from this cyclization and make higher quantities of the physiologically active form of creatine available to the metabolic activities of the muscle cells and yield a higher energy status. Obviously, the Magnesium Creatine Chelate could serve to provide effective quantities of bioavailable magnesium, which along with its many other effects, will work intensely along with creatine to increase the muscle's ability to generate and recycle energy in the form of ATP.
The loading dose for creatine is a very large one; and even its subsequent maintenance dose remains quite high. Based upon the studies which have indicated that 20 grams per day for 2 weeks will increase muscle creatine by about 20%, and considering an average loss of 2 grams of creatinine per day, would indicate a relative creatine absorption of 15.4%. At most, the maximal rate of creatine absorption was found to be 32%, and this was on the first two days of the loading phase.
Given the low relative absorption rate for creatine, researchers theorized that the formation of a Magnesium Creatine Chelate could improve the absorption characteristics for the creatine.
In addition, the combining of magnesium and creatine would harness together two separate nutritional forces that have been shown to have positive effects on the heart, energy and muscular performance.
The following Fig. 3 summarizes the above:
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Magnesium Chelate Study
In a controlled clinical study (available upon request), Magnesium Creatine Chelate was compared to creatine monohydrate, as well as creatine given along with magnesium. This study indicates that the Magnesium Creatine Chelate out performs creatine monohydrate, as well as creatine monohydrate given with magnesium by a wide margin. Magnesium Creatine Chelate enhances the body's ability to generate and regenerate the ATP needed to provide the energy needed for muscular performance.
In the study, Magnesium Creatine Chelate outperformed creatine, as well as combined creatine given with magnesium. Given the roles that magnesium and creatine play in the generation of energy needed for muscular performance, it would make sense that a substance that provides both magnesium and creatine in a synergistic form would outperform creatine alone.
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Magnesium Chelate Benefits:
- Formation of Magnesium Creatine Chelate protects creatine from the cyclization of creatine to creatinine in the acidic pH of the stomach.
- Chelate provides more active creatine to the bloodstream for subsequent incorporation into the cells of the muscle.
- Chelate provides magnesium, which is involved in more energy producing systems than creatine, plus creatine requires magnesium for its energy producing cycle.
- High doses of creatine are not required, since the chelate is not susceptible to acidic cyclization.
- Gastric disturbances are eliminated since only doses approximately 20% of what would be needed with creatine monohydrate are required.
- Sugar dosing is not required to effect efficient absorption, since insulin spiking it is not involved in its absorption.
- Lipogenesis (fat generation) is not stimulated, since insulin spiking is completely unnecessary.
- The body can remain in a glucagon dependant mode, resulting in fat flowing away from adipose tissue for use as a source of energy with the result being an increase in lean body mass ratio. Invalid Link Removed
Concluding Remarks
How much better Magnesium Creatine Chelate works as a performance enhancing nutrient, as compared to creatine monohydrate, is being heavily evaluated. It certainly appears to offer some real advantages. These advantages may stem from the magnesium bonding to the creatine in a way that limits the irreversible cyclization of creatine to inactive congener creatinine. This would enhance the amount of active creatine available for absorption. It may be that the magnesium chelate from of creatine eliminates creatine's need for an insulin spike for maximum muscle tissue retention. A true synergy of magnesium's and creatine's physiological effects, along with a "tissue targeting" phenomenon that has been observed with other chelates may be taking place. Two new human studies have recently concluded and when analyzed, may cast further light on the effectiveness of Magnesium Creatine Chelate. One study is under the direction of Dr. Robert DiSilvestro at Ohio State University, and the other is being conducted under the leadership of Dr. Lorrie Brilla at Western Washington University.
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References
- Feldman E. "Creatine: A Dietary Supplement and Ergogenic Aid", Nutritional Reviews, Vol 57 No. 2:45-50, 1999.
- Clark JF, "Creatine: A Review of Its Nutritional Applications in Sports", Nutrition, Vol 14, No. 3, 322-324, 1998.
- Harris Rd, Soderlund K. Hultman E, "Elevation of Creatine in Resting and Exercising Muscle of Normal Subjects by Creatine Supplementation", Clin Sci 1992, 83:367.
- Green Al, Hultman E. MacDonald IA, Sewell DA, Greenhaff RI., "Carbohydrate Ingestion Augments Skeletal Muscle Creatine Accumulation During Creatine Supplementation in Man", Am J Physiol 1996: 271:E821.
- Vandengerg K. Gellis N, Vanleemputte M, et al, "Caffeine Counteracts the Ergogenic Action of Muscle Creatine Loading", J Appl Phys 1996; 80:452-457.
- S. Ferraro et al; Clin. Cardiol. 19, 9, 699-703 (1996)
- M. Cafiero et al; Clin Ter. 144, 4, 34-8 (1994).
- D.J. Chambers et al; Ann. Thorac. Surg. 6, 1, 67-75 (1996).
- P. guichard, J.E. Burkhardt and N.W. Seidler; Med. Hypotheses 45, 1, 41-44 (1995).
- M. Daniel Becque, John D. Lochmann, and Donald R. Melrose "Effects of oral creatine supplementation on muscular strength and body composition", Med & Sci in Sports & Exercise, 32, No.3, 654-658 (March 2000).
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