"however recent studies suggest that the t10, c12 isomer may induce complex and specific changes which prevent the fat cells functioning correctly, resulting in reduced levels of body fat. Interestingly when the c9, t11 CLA isomer was compared separately it appeared to have completely opposite effects to the t10, c12 isomer."
"The results of the study found that final levels of body fat were not significantly affected by either form of CLA. However, the c9, t11 CLA isomer was found to increase the size of fat cells whilst the CLA mixture did not affect the size or number of fat cells."
"The t10, c12 CLA isomer was found to significantly reduce fat tissue regardless of background diet however, when the c9, t11 isomer was used, no effect was seen."
"Dietary CLA, composed of a mixture of isomers but predominantly the c9, t11 isomer was found to significantly reduce deposition of fat under the skin."
"The c9, t11 CLA isomer was found to have no effect. Dr Park then went on to discuss studies investigating the effects of CLA on body fat. Supplementation of the t10, c12 CLA isomer in animal models tends to give a fairly consistent and significant reduction in body fat, however studies in humans have reported farless dramatic results."
"He began by discussing how several studies have shown that mice fed a diet supplemented with t10, c12 CLA may experience reduced deposition of body fat but appear to develop an increased deposition of fat in the liver instead."
"In addition, the t10, c12 CLA isomer was found to cause unwanted changes in fat cell function and breakdown of liver fats which were partially alleviated by combination with the c9, t11 CLA isomer."
"The t-10 c-12 CLA isomer has also been connected to helping to reduce body fat in animal studies."
