I have not, but I have been on HCG long term - I don't know if that's relevant to your experiences, so I apologize if not. I know the two treatments are often used for the same things and are sometimes used concurrently, so this may be useful or may not be. I have been on 1000iu 2x/wk subQ with .5mg anastrozole at time of injection of HCG for about five-six years now as treatment for secondary low T (HCG is a replacement for LH, HMG is a replacement for FSH, I had low LH and FSH). No side effects. Testosterone holding steady in the 600-700ng/dL range with E2 in the 20-30pg/mL range, blood work every six months since starting treatment. Still fertile based on most recent semen sample last month.