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.HALFLIFE VS POTENCY

skull

skull

Active member
.whats better to have a pretty good compound with a long halflife--or a very good compound with a very short halflife? how many times a day can a androgen receptor be activated? another words if you take a compound and it activates the AR ;by the..time it comes around again [second pass] is the same .AR ready to be activated again?
 
Doesn't really matter. If it has short half-life, you just have to dose it often enough if you want to maintain stable blood levels.
 
the ARs don't activate.. the androgen latches onto it and sends a signal to the body to do certain things. there are billions of receptors in the body. once the androgen latches onto the receptor its half life dictates how long it will take to completely dissolve in the body. so .. lets say u have a AR with a hormone sitting in it.. after a couple days when that molecule is gone that receptor is now able to accept another molecule. that said.. you don't just take a hormone and fill up all your receptors at once. it just doesn't happen like that.. its more like all the illegal aliens crossing the border.. they have to find a bus to get them to their destination.. until then they just float around in holding. same thing with andorgens.. they float around the body until they find a receptor to latch on to.

this is why you have to eat some androgens every couple hrs to reach a saturation point.
 
xR1pp3Rx said:
the ARs don't activate.. the androgen latches onto it and sends a signal to the body to do certain things. there are billions of receptors in the body. once the androgen latches onto the receptor its half life dictates how long it will take to completely dissolve in the body. so .. lets say u have a AR with a hormone sitting in it.. after a couple days when that molecule is gone that receptor is now able to accept another molecule. that said.. you don't just take a hormone and fill up all your receptors at once. it just doesn't happen like that.. its more like all the illegal aliens crossing the border.. they have to find a bus to get them to their destination.. until then they just float around in holding. same thing with andorgens.. they float around the body until they find a receptor to latch on to.

this is why you have to eat some androgens every couple hrs to reach a saturation point.
Click to expand...
--------------------------------------------------------------------------------ok so lets say you take oral trest, it .has very short HL[ 90 min?] but it binds very well to AR----...the same AR would be able to except more trest in 90 min??
 
skull said:
--------------------------------------------------------------------------------ok so lets say you take oral trest, it .has very short HL[ 90 min?] but it binds very well to AR----...the same AR would be able to except more trest in 90 min??
Click to expand...

no. 90 mins is the half life. that's means half of what you ingested is still in circulation. 90 mins after that there would be half that amount and so on and so on.
 
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