I like the forms of some of the compounds in the formula.
For example, Vitamin E is available as the superior d-alpha tocopheryl-succinate and mixed tocopherols forms versus the standard d-alpha tocepheryl form found in some other products; Vitamin B6 is available as the superior pyridoxal 5' phosphate versus the basic pyridoxine in some other products (the body must convert pyridoxine into pyridoxal 5' phosphate to be able to use vitamin B6); Vitamin B12 is available as the vastly superior methylcobalamin form, the form the body can use directly, compared to the standard cyanocobalamin form in some other products that needs to be converted first to methylcobalamin. Then check out the bio-active form of Folic Acid used (methylfolate) to ensure superior performance. And so on. This formula is ahead of the pack in many dimensions.
I truly love to see the full spectrum of Vitamin E available in a formula. The ideal would be to use not only the alpha d-tocopherol and mixed tocopherols ((d-gamma tocopherol, d-delta tocopherol, d-beta tocopherol), but also tocotrienols (alpha, beta, gamma, and delta). Tocotrienols, can, however be supplemented additionally. This complex should ensure the optimal benefits of vitamin e supplementation (potent anti-oxidant and lipid peroxidation activities) are adequately captured. Tocotrienols are, by the way, the compounds that have shown the most significant potential, not only to reduce the incidence of breast cancer, but also to check the propagation of existing breast cancer cells.
The addition of Vitamin K1 is cool stuff. As is well known, Vitamin K has two broad forms, K1 and K2. K1 is the standard form, whereas K2 is the more advanced form. Vitamin K2 is also referred to as menaquinones. The two main forms of K2 (menaquinones) are menaquinone-2 and menaquinone-7. As it turns out, menaquinones are known to be significantly more potent than standard K1. In particular, menaquinones are up to ten times better absorbed than K1, last considerably longer in our system (up to 72 hours, compared to about 8 hours for K1), and are consequently dramatically more bioactive. K1, nevertheless, is still pretty cool stuff.
In a properly functioning metabolic environment, for instance, only minuscule amounts of calcium should be in the blood stream, because calcium should preferably be bound to bones. If, due to some dysfunction, however, and calcium begins to circulate in our blood, this eventually leads to the accumulation of layers of calcium deposits in the arterial walls, a process known as calcification. Furthermore, if calcium circulates in the blood, and does not sufficiently bind to bones, bone structure and density are compromised (weakened). Osteoporosis may develop as a consequence. These outcomes also suggest that calcium-regulating proteins do not function properly. In any case, the calcification deprives the arteries of their flexibility and elasticity, such that a variety of cardiovascular conditions, including high blood pressure, arteriosclerosis, and so on may develop, not to mention the likelihood of osteroporosis. But because menaquinones are particularly effective at directing calcium from the blood to the bones, and because Vitamin K is necessary for the proper functioning of calcium-regulating proteins, a sufficient intake of vitamin K may eventually eliminate circulating blood calcium, direct this calcium to bones, and support the proper functioning of calcium-regulating proteins. This will improve cardiovascular functioning as well as bone health.
Furthermore, I like there is no iron. Iron is one compound that can be easily overdosed with sometimes lethal consequences. If iron is added, then copper should also be added in greater quantity, so they adequately support each other.
Potassium is one mineral that one should be careful not to overdose. An important electrolyte, though. If you take diuretic compounds before bed, you need potassium, as diuretics deplete potassium stores.The amount in the product is spot-on.
Calcium can also be obtained from nutrition and other compounds athletes take. Too much calcium and you would need to increase magnesium accordingly.
Selenium is one of the most powerful anti-cancer supplements around. Supplementing with adequate amounts of selenium daily can dramatically cut our susceptibility to cancer (proatate, colon, lungs, and so on). The USA belongs, by the way to the group of countries with relatively lower consumption of selenium (about 200mcg per day). The Japanese consume on the average 400mcg per day, and the population in Greenland about 1 280mcg per day (and they are still intact)! Overdose is relative and personal. Some symptoms of overdose include garlic-smelling breath, loss of hair and finger nails, liver problems, loss of urine, and so on. Apart from the amount, the form is also important. L-Selenomethionine, Sodium Selenite, and Selonodiglutathione are solid advanced forms.
Zinc is crucial in more than 100 or so metabolic processes. Again, the form is important. Zinc monomethionine is a pretty advanced one.
In my opinion, Vitamin D, especially, in its active form (cholecalciferol, D3) as a hormone could be dosed higher, especially in areas that have comparatively less sunshine. About 15 minutes per day in the sun can also provide all the vitamin D we need per day. For sedentary individuals, and for some athletes, supplementation is crucial.
Overall, the formula looks quite exciting.