I would dose the LR as far away from carbs as possible!! Carbs will greatly inhibit the Yohimbine from doing it's job! I used to take it before fasted morning cardio(AWESOME TIME TO TAKE IT) along side DCP. My next LR/DCP dose would come about 5-6 hours later, which was usually about 1hour b4 my lunch. I would then take My last DCP dose b4 evening workout. As far as dosages, I went with 4LR/day, and 6 DCP/day. This combo is FANTASTIC by the way!