I am now in a lean mass phase with a small t3 dose.25-30 mcgs as a nutrient partitioner.Most my my training has been done in a low carb/deficit state because of my love hate relationship with my genetics.Father is a rather large man and has been for most of his life.Mom is the same.Needless to say I lose alot of muscle staying lean or atleast trying to.Carbs are my enemy so to speak and excess calories seem to store quickly. So far my first dose today and I feel better after eating carbs than I used to,not tired at all.
Over the next 3 weeks I'll be playing around with this serious drug.Here are some myths/misconceptions about t3 I have found in my research.
T3 causes damage to your thyroid myth
It dose indeed cause your natural t3 production to stop but you do recover as long as you don't go overboard.25mcgs ED even over 3 months won't damage your thyroid permanently .Of course this is for the general population mind you.If you go above 150mcgs thats getting a little much.Although rebound weight gain is almost writen in stone.
T3 burns muscle!
This is true at high doses (above 50 mcgs) coupled with low calories.At lower doses this shouldn't be a problem as long as your eating enough OVER maint level.
T3 is a cutting drug and nothing more!
Not true,nutrient partitioning aspect is great!Can be used in bulk/lean mass for better breakdown of/partitioning fats,carbs and protein.
Heres info on the effects
Effects of T3
T3 increases the basal metabolic rate and, thus, increases the body's oxygen and energy consumption. The basal metabolic rate is the minimal caloric requirement needed to sustain life in a resting individual. T3 acts on the majority of tissues within the body, with a few exceptions including the spleen and testis. It increases the production of the Na+/K+ -ATPase and, in general, increases the turnover of different endogenous macromolecules by increasing their synthesis and degradation.
Protein
T3 stimulates the production of RNA Polymerase I and II and, therefore, increases the rate of protein synthesis. It also increases the rate of protein degradation, and, in excess, the rate of protein degradation exceeds the rate of protein synthesis. In such situations, the body may go into negative ion balance.
Glucose
T3 potentiates the effects of the ?-adrenergic receptors on the metabolism of glucose. Therefore, it increases the rate of glycogen breakdown and glucose synthesis in gluconeogenesis.
Lipids
T3 stimulates the breakdown of cholesterol and increases the number of LDL receptors, thereby increasing the rate of lipolysis.
Heart
T3 increases the heart rate and force of contraction, thus increasing cardiac output, by increasing ?-adrenergic receptor levels in myocardium. This results in increased systolic blood pressure and decreased diastolic blood pressure. The latter two effects act to produce the typical bounding pulse seen in hyperthyroidism.
Development
T3 has profound effect upon the developing embryo and infants. It affects the lungs and influences the postnatal growth of the central nervous system. It stimulates the production of myelin, the production of neurotransmitters, and the growth of axons. It is also important in the linear growth of bones.
Neurotransmitters
T3 may increase serotonin in the brain, in particular in the cerebral cortex, and down-regulate 5HT-2 receptors, based on studies in which T3 reversed learned helplessness in rats and physiological studies of the rat brain.
T3 has a short half life!
This may be started by doctors,bro science or w/e but the half life of Liothyronine or cytomel is 2.5 days.Confirmed by a local pharmacy and a doctor and the internet.No need to split dosage unless you feel hypo symptoms caused by the bigger doses(50-75 mcgs or higher)
T3 must be used with an anabolic so you don't waste away!
Again not for the lower doses but for the higher doses you MUST to retain even alittle muscle.At50 to 100 plus mcgs you will be burning muscle even with anabolics.This is a fact.
You must taper up and down!
God I wish this would die.After hundreds of post and everyone posting the same reason(perm thyroid damage) I found one that lead me to the conclusion this is a myth.Confirmed it aswell.Just like with clen,no need to tapper up or down but the sides can be a bit much if you don't.Also it's easier for your thyroid to recover if you come down slowly but you still can recover if you don't.This is one of those drugs where you need to acess how it reacts with your body.Start at 25 mcgs cause nobody wants to faint/throw it up by jumping right to 100mcgs.
Interesting read about Regulation of Human Skeletal Muscle Gene Expression by Thyroid Hormone
http://genome.cshlp.org/content/12/2/281.full
I hope that cleared up some foggy info and thank you for reading.Sub for updates on my results.
