Exemestane solubility?

[UNX]

I have some raw exemestane powder. I want to make a solution to dose it more accurately.
What's the best solvent I can use? I know it's not soluble in polar solvents like water or DMSO. It's soluble in methanol, but I want a solvent that won't kill me. In some oil solubility is low, like olive oil. I have to try in ethanol yet.

 

[Renew1]

I have some raw exemestane powder. I want to make a solution to dose it more accurately.
What's the best solvent I can use? I know it's not soluble in polar solvents like water or DMSO. It's soluble in methanol, but I want a solvent that won't kill me. In some oil solubility is low, like olive oil. I have to try in ethanol yet.

I'd try Ethanol.

 

[UNX]

Well, I did a quick test with ethanol and works, now I have to get some food grade ethanol to see if I can achieve a 50 mg/ml solution.

 

[Renew1]

Well, I did a quick test with ethanol and works, now I have to get some food grade ethanol to see if I can achieve a 50 mg/ml solution.

I know stores that carry that substance.

 

[suavmcgauv]

Polyethylene glycol 6000 (PEG 6000), could be a harder to acquire alternative if you are looking to avoid ethanol.

 

[UNX]

@Renew1 I just distilled denaturated ethanol and it seems to solve fine up to 25 mg/ml.

@suavmcgauv I read about PEG6000 in a paper, maybe it's worth it because I have a lot of exemestane.

 

[Renew1]

@Renew1 I just distilled denaturated ethanol and it seems to solve fine up to 25 mg/ml.

@suavmcgauv I read about PEG6000 in a paper, maybe it's worth it because I have a lot of exemestane.

Well ... that works.
Personally I'd have just grabbed a drinkable bottle off the store shelf.

 

[UNX]

Well ... that works.
Personally I'd have just grabbed a drinkable bottle off the store shelf.

Yes, but I guess the higher the alcohol content, the higher the solubility. Anyway, I'll try to get food grade alcohol just in case there's some methanol contamination.