Estrogen vs prolactin

[Mraesthetic12]

How is one able to know if theyre gyno is prolactin or estrogen based? For example if one was running tren with test, one could assume that the gyno is prolactin based due to the tren but then again testosterone can cause estrogen gyno. Does one take caber AND aromasin?

 

[CatSnake]

How is one able to know if theyre gyno is prolactin or estrogen based? For example if one was running tren with test, one could assume that the gyno is prolactin based due to the tren but then again testosterone can cause estrogen gyno. Does one take caber AND aromasin?

prolactin based gyno typically involves lactation.

if you're taking a 19-nor based androgen and get gyno, then it would be wise to treat for elevated prolactin. well, it would be wise to take a preventative dopamine agonist, in the first place....

however, it merits mentioning that elevated E2 can raise prolactin as well. it's not common, but regardless, is pretty easily treatable (and preventable)....

most modern versions of tren aren't known for prolactin, but I believe either Fini or Parabolan was.

anyway, if you're dealing with gyno while on-cycle, you could take raloxifene for the actual gyno. then an AI to address elevated E2, and a DA for the elevated prolactin.... another option while on cycle is andractim (a topical DHT cream) as well.

 

[Mraesthetic12]

prolactin based gyno typically involves lactation.

if you're taking a 19-nor based androgen and get gyno, then it would be wise to treat for elevated prolactin. well, it would be wise to take a preventative dopamine agonist, in the first place....

however, it merits mentioning that elevated E2 can raise prolactin as well. it's not common, but regardless, is pretty easily treatable (and preventable)....

most modern versions of tren aren't known for prolactin, but I believe either Fini or Parabolan was.

anyway, if you're dealing with gyno while on-cycle, you could take raloxifene for the actual gyno. then an AI to address elevated E2, and a DA for the elevated prolactin.... another option while on cycle is andractim (a topical DHT cream) as well.

What if what you have is prolactin gyno, but its not fully developed to the point of lactation? For example my friend ran trenavar last year and got gyno but he didnt lactate. In that case do you just take both caber and aromasin or one at a time?

 

[CatSnake]

What if what you have is prolactin gyno, but its not fully developed to the point of lactation? For example my friend ran trenavar last year and got gyno but he didnt lactate. In that case do you just take both caber and aromasin or one at a time?

well, if his E2 is still high, then an AI would help prevent the gyno from getting worse and might help reduce it. however, if his E2 is in a normal range (20-30), then an AI isn't gonna do anything...

same thing with a dopamine agonist and prolactin.... if his prolactin is still high, then that could help. but if it's normal, then again it won't do much.

the above list andractim is not a good choice for off-cycle management, as it does affect the HPTA.


the best choice here would be raloxifene (60 mg/day) or tamoxifen (10-20 mg/day), as they can actually bind to the ER in the breast tissue.

 

[CatSnake]

Beneficial effects of raloxifene and tamoxifen in the treatment of pubertal gynecomastia.
Lawrence SE1, Faught KA, Vethamuthu J, Lawson ML.

OBJECTIVES:
To assess the efficacy of the anti-estrogens tamoxifen and raloxifen in the medical management of persistent pubertal gynecomastia.

STUDY DESIGN:
Retrospective chart review of 38 consecutive patients with persistent pubertal gynecomastia who presented to a pediatric endocrinology clinic. Patients received reassurance alone or a 3- to 9-month course of an estrogen receptor modifier (tamoxifen or raloxifene).

RESULTS:
Mean (SD) age of treated subjects was 14.6 (1.5) years with gynecomastia duration of 28.3 (16.4) months. Mean reduction in breast nodule diameter was 2.1 cm (95% CI 1.7, 2.7, P <.0001) after treatment with tamoxifen and 2.5 cm (95% CI 1.7, 3.3, P <.0001) with raloxifene. Some improvement was seen in 86% of patients receiving tamoxifen and in 91% receiving raloxifene, but a greater proportion had a significant decrease (>50%) with raloxifene (86%) than tamoxifen (41%). No side effects were seen in any patients.

CONCLUSION:
Inhibition of estrogen receptor action in the breast appears to be safe and effective in reducing persistent pubertal gynecomastia, with a better response to raloxifene than to tamoxifen. Further study is required to determine that this is truly a treatment effect.

 

[Volvo140G]

I used tamoxfien, 3 months at 20 mg and tapered away slowly the last few weeks to treat some rebound gyno from a cycle. Used aromasin in conjunction as well.

The lumps (2 in right nipple) were reduced to mere specks. I have to try real hard to even feel them now, they just feel like a pin point/single grain of sand. Was extremly successful and id reccommend it as a course of treatment for anyone.

Ralox is apparantly more effective but I had such success with tamox id never stray should I find myself in such a situation again.

 

[GreekTheBrick]

Also bloods is a more appropriate way to find out whats going on and address it to the point. Still CatSnake covered all things to consider in case bloods arent in the picture

 

[Mraesthetic12]

prolactin based gyno typically involves lactation.

if you're taking a 19-nor based androgen and get gyno, then it would be wise to treat for elevated prolactin. well, it would be wise to take a preventative dopamine agonist, in the first place....

however, it merits mentioning that elevated E2 can raise prolactin as well. it's not common, but regardless, is pretty easily treatable (and preventable)....

most modern versions of tren aren't known for prolactin, but I believe either Fini or Parabolan was.

anyway, if you're dealing with gyno while on-cycle, you could take raloxifene for the actual gyno. then an AI to address elevated E2, and a DA for the elevated prolactin.... another option while on cycle is andractim (a topical DHT cream) as well.

If i were to run trenavar should i buy caber? Or should aromasin due the trick?

 

[CatSnake]

If i were to run trenavar should i buy caber? Or should aromasin due the trick?

if trenavar elevates prolactin, then you need a DA. if it elevates E2, then you need an AI.

I don't know enough about trenavar to tell you what to expect there, tho.

 

[warbird01]

It can be very hard to tell without bloods since both are so intertwined.