I just want to make a couple of points about methyl epithiostanol, I know that since this is my first post I couldn't possibly know anything but I am a BSc PhD MD and my life's work has been the laboratory synthesis of biochemical signaling molecules such as androgens and anabolic steroids. I have acted as a consultant to many "supplement" companies and I have come to find the supplement is actual reference to the fact the "supplement" their income with you hard earned money.
Point #1: methylepithiostanol is a cytotoxic, antineoplastic a.k.a. a chemotherapy treatment designed for one reason: to kill quickly dividing cells. It does this by inhibiting the unwinding of the DNA helix preventing DNA replication and thus cell division. The cell dies. Your muscle cells just might come under the fast growing definition if you are in an anabolic state.
Point #2: for a while I made money by consulting with supp's companies to find them, and I quote from a prominant CEO "we want <steroids> which have chemical name recognizable as similar to common steroids, and try to find citations of it doing anything better than testosterone, I don't care if its in bumblebee sphincter muscle, I want to say its binds something better"
they do not care if it works or if it will kill you in ten years because they will be retired in the bahamas. Its all about expired patent searches, you couldn't possibly think that some geek like me didn't know about this stuff eons ago. Its so hazardous even for chemo its only allowed for medical use in China. This is no breakthrough molecule
cite: British Patent 977 599 (1964) for preparation to Komeno followed by u.s. patent 3230215 to Shionogi (1964-66)
toxicity study eidem, ibid. 805, C.A. 80, 66865u (1974)
studied extensively in the 70's Antitumor effect in mice / effectiveness in breast cancer / teratogenicity study
True scientific breakthrough of the new millenium. Chemotherapy drugs are among the hardest on the body science has to offer and they've got you taking one we can't even prescribe to a dog. Whats next, the arsenate salt of androdeekkaboldendion-abolesterone?
One more point if I haven't already been banned. The statements made about how this or that is 700 million times more anabolic than testosterone is all semantics. A study came out when i was still in the crib with a rubber tit dangling from my mouth, it measured the binding affinity of many "anabolic" molecules vs. that of testosterone. The target receptors? The diaphragm muscle of some type of bird or rodent, can't remember. Smooth not skeletal muscle, completely different receptor concentrations and they were all over the place with different solvent systems, lack of control, the works. This paper has fueled the PH business for 15 years and not one person has ever stood up and argued it.
I will make this statement and you can quote me, I have made every steroid you can think of from the most basic of feedstock and ran many tests with them on binding affinites , there is nothing man can create synthetically that will bind the androgen receptor stronger than the molecule we have spend millions of years of evolution developing invivo, especially when these synthetic molecules lack even the same orientation of testosterone.
PH and PS are nonsensical terms, what does prosteroid mean, if it is of the cholesterol skeleton it is a steroid, a prohormone undergoes change to become "anabolic" which makes it a pre-hormone, a prohormone would illicit a response of release of hormone, like a signaler or cofactor to release of the hormone by a specific cell or gland of the endocrine system. A prohorme would influence the level of hormone release, not become a hormone.
