I am on Anavite and Fitt Men (stacked) to get the proper dose. Anavite has great trace minerals but it is lacking in Calcium and Magnesium. Also low in copper and zinc. Fitt Men from Formutech certainly picks up the spare in this respect. B-Vitamins alone can detoxify estrogen in the liver and destroy androgens!
I want to maximize my testosterone boosters and prohormone cycle so I am stocking up on multi-vitamins!
EFFECT OF VITAMIN B COMPLEX DEFICIENCY ON INACTIVATION OF ESTRONE IN THE LIVER
MORTON S. BISKIND GERSON R. BISKIND
Endocrinology, Volume 31, Issue 1, 1 July 1942, Pages 109–114, https://doi.org/10.1210/endo-31-1-109
Published: 01 July 1942 Article history
Abstract
IN A PRELIMINARY NOTE (i) we have reported that deficiency of the vitamin B complex in female rats markedly diminishes the inactivation of estrone in the liver. Further study of this phenomenon, which is the subject of the present communication, shows that the inactivation mechanism, impaired by vitamin B deficiency, may be restored by addition of brewers yeast to the diet. Subsequent depletion of the diet is again capable of interfering with the destruction of estrone in the liver. The flow of estrogen through this organ can thus be controlled at will, by withholding the vitamin B complex or by restoring it to the diet.
Within a few years after the isolation of the first crystalline estrogen, it became apparent that this and related compounds are rapidly inactivated in the body. Much of the early literature has been reviewed elsewhere (a). Perhaps the earliest clue to the possibility that estrogen is destroyed by an organ or organs in the portal circulation was the observation by Evans and Burr in 1926 (3) that estrogen was more-effective when given subcutaneously than when administered intraperitoneally.
INACTIVATION OF TESTOSTERONE PROPIONATE IN THE LIVER DURING VITAMIN B COMPLEX DEFICIENCY. ALTERATION OF THE ESTROGEN-ANDROGEN EQUILIBRIUM1
MORTON S. BISKIND GERSON R. BISKIND
Endocrinology, Volume 32, Issue 1, 1 January 1943, Pages 97–102, https://doi.org/10.1210/endo-32-1-97
Published: 01 January 1943 Article history
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Abstract
IN PREVIOUS publications (1–3) we have reported that deficiency of the vitamin B complex in female rats seriously impairs the estrogen-inactivating function of the liver, and that this function can be restored by the addition of brewers2 yeast to the diet. The investigation presented here is concerned with the effect of vitamin B deficiency on hepatic inactivation of testosterone propionate. Unlike the estrogens, inactivation of this androgen in the liver is not significantly diminished in vitamin B complex deficiency.
It has been shown (4–6) that testosterone propionate and other androgens are normally inactivated in the liver. When pellets of androgen were implanted in the spleens of previously castrated rats so that the absorbed steroid must pass through the liver before reaching the systemic circulation, no androgenic effect could be detected. If the spleen containing the pellet was subsequently transplanted subcutaneously, and after establishment of a collateral circulation, its pedicle ligated, the specific effect became evident. Burrill and Greene (7) and Selye. (8) have provided confirmatory evidence that androgens are inactivated in the liver.
I want to maximize my testosterone boosters and prohormone cycle so I am stocking up on multi-vitamins!
EFFECT OF VITAMIN B COMPLEX DEFICIENCY ON INACTIVATION OF ESTRONE IN THE LIVER
MORTON S. BISKIND GERSON R. BISKIND
Endocrinology, Volume 31, Issue 1, 1 July 1942, Pages 109–114, https://doi.org/10.1210/endo-31-1-109
Published: 01 July 1942 Article history
Abstract
IN A PRELIMINARY NOTE (i) we have reported that deficiency of the vitamin B complex in female rats markedly diminishes the inactivation of estrone in the liver. Further study of this phenomenon, which is the subject of the present communication, shows that the inactivation mechanism, impaired by vitamin B deficiency, may be restored by addition of brewers yeast to the diet. Subsequent depletion of the diet is again capable of interfering with the destruction of estrone in the liver. The flow of estrogen through this organ can thus be controlled at will, by withholding the vitamin B complex or by restoring it to the diet.
Within a few years after the isolation of the first crystalline estrogen, it became apparent that this and related compounds are rapidly inactivated in the body. Much of the early literature has been reviewed elsewhere (a). Perhaps the earliest clue to the possibility that estrogen is destroyed by an organ or organs in the portal circulation was the observation by Evans and Burr in 1926 (3) that estrogen was more-effective when given subcutaneously than when administered intraperitoneally.
INACTIVATION OF TESTOSTERONE PROPIONATE IN THE LIVER DURING VITAMIN B COMPLEX DEFICIENCY. ALTERATION OF THE ESTROGEN-ANDROGEN EQUILIBRIUM1
MORTON S. BISKIND GERSON R. BISKIND
Endocrinology, Volume 32, Issue 1, 1 January 1943, Pages 97–102, https://doi.org/10.1210/endo-32-1-97
Published: 01 January 1943 Article history
Cite
Permissions
Share
Abstract
IN PREVIOUS publications (1–3) we have reported that deficiency of the vitamin B complex in female rats seriously impairs the estrogen-inactivating function of the liver, and that this function can be restored by the addition of brewers2 yeast to the diet. The investigation presented here is concerned with the effect of vitamin B deficiency on hepatic inactivation of testosterone propionate. Unlike the estrogens, inactivation of this androgen in the liver is not significantly diminished in vitamin B complex deficiency.
It has been shown (4–6) that testosterone propionate and other androgens are normally inactivated in the liver. When pellets of androgen were implanted in the spleens of previously castrated rats so that the absorbed steroid must pass through the liver before reaching the systemic circulation, no androgenic effect could be detected. If the spleen containing the pellet was subsequently transplanted subcutaneously, and after establishment of a collateral circulation, its pedicle ligated, the specific effect became evident. Burrill and Greene (7) and Selye. (8) have provided confirmatory evidence that androgens are inactivated in the liver.