DHEA solubility

B5150

B5150

Legend
I am looking to DHEA to my TRT protocol. I am only looking to dose at 50mg/d.

My buddy Matt carries his CNW Invalid Link Removed. This is so cost effective I cannot see buying capped product.

I have 3 sizes (all too big) of Cap-m-Quick complete sets and don't want to buy another one or really want to mess with filler.

I thought of just producing a solution/suspension in EVOO at 25mg/ml to 50mg/ml.

Anyway...DHEA solubility?
 
I dunno about for an oral solution - but it worked fine in Penetrate for transdermal application.
(Got quite a bit in a bottle too - like 15+ grams.)
 
I'd go transdermal. I have heard oral bioavailability is pretty poor.
 
It's most sol in alcohol (and ether) for trans but you'd be surprised how orally active it is too. I usually just eat it and it feels pretty strong, even under 200mg.
 
jonny21 said:
"I have heard oral bioavailability is pretty poor."
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"Oral absorbtion of DHEA is excellent. The volume of distribution is 17.0-38.5 L"

Invalid Link Removed

I don't know what's wrong with the link, but I was just on the page.
 
B5150 said:
I am looking to DHEA to my TRT protocol. I am only looking to dose at 50mg/d.

My buddy Matt carries his CNW Invalid Link Removed. This is so cost effective I cannot see buying capped product.

I have 3 sizes (all too big) of Cap-m-Quick complete sets and don't want to buy another one or really want to mess with filler.

I thought of just producing a solution/suspension in EVOO at 25mg/ml to 50mg/ml.

Anyway...DHEA solubility?
Click to expand...

I personally wouldn't worry about solubility. Just give it a good shake and it should fall into a suspension just fine. You may dissolve it in a small amount of alcohol first before adding it to your oil, at least that's what I would do. My last batch of Nolva was done that way in grapeseed oil. Worked like a charm. But yeah, I take my DHEA orally with a noticeable effect at 100mg ed. I have heard some of it's metabolites are less orally active such as 7-OXO so I always use it transdermally. FWIW
 
bpmartyr said:
I personally wouldn't worry about solubility. Just give it a good shake and it should fall into a suspension just fine. You may dissolve it in a small amount of alcohol first before adding it to your oil, at least that's what I would do. My last batch of Nolva was done that way in grapeseed oil. Worked like a charm. But yeah, I take my DHEA orally with a noticeable effect at 100mg ed. I have heard some of it's metabolites are less orally active such as 7-OXO so I always use it transdermally. FWIW
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Good info bp.... :thumbsup:
 
jonny21 said:
I'd go transdermal. I have heard oral bioavailability is pretty poor.
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Just for ****s and giggles.

Penatrate is $13.00 for 240ml = $0.05/ml
DHEA $10.00 for 25g = $0.40/g or $0.02/50mg

$0.07/50mg/ml = Cost analysis 71% for carrier and 29% for active

Key word analysis ;)

I have grown so tired of TD's. I desire more invasive action :)
 
You could look into a DHEA supposetory?

I'm sure Motiv8er will serve as the administrator of said DHEA supposetory...
 
NO HYPE said:
"Oral absorbtion of DHEA is excellent. The volume of distribution is 17.0-38.5 L"

Invalid Link Removed

I don't know what's wrong with the link, but I was just on the page.
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Excellent, what does that equate to in percentages. From what I have read, it ranges from 3% to excellent to unknown.

I hear you B, the whole "it puts the lotion on its skin" thing gets played out kinda quick. Works though. I could have sworn I experienced some localized fat loss at application sites.
 
jmh80 said:
:icon_lol:

The good Doc loves me.
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Yeah, but you're pushin' it buddy! :p

I still remember those silly pics you put up naming me as the most gay looking one... it's a good thing I love you. ;)
 
Moyer said:
so just shakin it up in oil should be fine?
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Yes. As long as it's well dispersed and not too clumpy, it doesn't matter what it's in. Even distilled water would be fine.
 
Good deal. Thanks D! Last time I capped 'em & I had to use a filler. It wasn't that bad using a coffe grinder to mix it, but this would be a whole lot easier.
 
jmh80 said:
You could look into a DHEA supposetory?

I'm sure Motiv8er will serve as the administrator of said DHEA supposetory...
Click to expand...

Glad I caught this...

I know coming from the U where you graduated, reeding an righting wernt heavly stressd. But if you red mine PMACIC threadz, you wood cee it was me who was plezured, not hern.


LOL :bb2:
 
thesinner said:
I wouldn't rely on that. I could've sworn it was rather non-polar.
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It's fairly polar but still no way close to water soluble. EtOH and Et2O are the best for it.
 
jmh80 said:
I didn't graduate from The U, Motiv8.

Good to hear you were pleasured.
Click to expand...

It was very good my friend. ;)
 
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