well, yes. additionally, DHEA and Pregnenolone are neuro steroids - you wouldn't want to increase brain activity when you're trying to rest.
we highly recommend a good body lotion to keep skin from getting irritated. I would wait 4-5 hours before applying over the top of the application spot though. I use a hemp/acai hydrating lotion at night when I'm using the gels. it's a formulation we're contemplating releasing for use with the gels