Cholestatic Jaundice & IgA Nephropathy Induced by OTC Muscle Building Agent Superdrol
- Thread starter rmag2447
- Start date
Lawhammer
New member
swoody said:Thats because this country is already on a witch hunt for any type of anabolic... so your right... and that's sad
I agree with you to an extent. A great example of the hysteria was when the US Senate held several days of hearings on the important subject of steroids in baseball – at a time when our country is at war, countries that hate us are developing nuclear weapons that will be aimed at us, the national debt is through the roof, US jobs are going oversees, millions are paying into social security but will never see benefits, US auto makers can’t seem to build a competitive product, Americans are going to Canada for prescription drugs due to cheaper prices, ect, ect.
Due to unjustified hysteria, the safer alternatives have all been made illegal, creating a market for grey area compounds that come with much worse sides. But that nevertheless does not make it right for a company to take advantage of the grey area in order to make money while knowingly compromising your health.
swoody
Member
Lawhammer said:
While I agree with you about how this nation's priorities are really screwed up right now, I don't care if supp companies make money off this stuff... for someone who actually did their homework and did proper post cycle therapy, liver support and knew this stuff wasn't like poppin a multi, they work, with little to no sides... that is IF whoever is using them takes responsibility for their actions and gets their ass covered with the proper support supps, and doesn't drink, etc. while they are on cycle... the only people who compromise their health is the morons that run an oral for 6 weeks
I guess my point is that the media is going to take advantage of ANY type of sports supplement making the news, bringing the hammer down on undeserving parties, cause as you said, that is where our countries priorities are right now. I just think it's wrong that the rest of us have to pay for the few people who's own ignorance gets them in trouble. And the sides are no worse than any other hormone-altering anabolic compound that have already been around for years... especially superdrol. This was a freak occurance, and it does not reflect the educated majority who uses it without compromising their health.wazupp91350
New member
MY son took superdrol for a month, and he is now in the hospital very sick, with liver damage, we did not really know why he was so sick, he is very yellow with Jandice and serious issues, just like CW Anderson had. I found a website, and low and behold the Superdrol is the cause, here is the article PLEASE IF YOU ARE TAKING THIS STOP NOW>>>>>>>>>>> A 23-yr-old Hispanic male bodybuilder without any known past medical history presented at the Maricopa Medical Center (MMC) with a 2-wk complaint of nausea, vomiting, decreased appetite, jaundice, RUQ a**ominal pain, pale stools, dark urine, and itching. Two months before the onset of his clinical symptoms, he had started using an OTC nutritional supplement for bodybuilders named anabolic extreme (superdrol) having methasteron as its active ingredient. He consumed 72 10-mg pills of superdrol, starting at one tablet daily for 2 wk followed by two tablets daily. He did not exceed the maximal suggested dose of 126 pills (10 mg each) that was recommended over a 6-wk period. He stopped using superdrol with the onset of diffuse skin itching. He did not report any history of alcohol, recreational drugs, or tobacco use. There was no family history of liver disease. He did not have any drug allergies.
On physical examination, his vital signs were stable. He was deeply icteric with several scratch marks noted throughout the trunk and lower extremities. He was overweight with a BMI of 28. The a**omen was slightly tender in the right upper quadrant with no evidence of ascites, hepatosplen*****ly, or a Murphy's sign.
At presentation, labs revealed a total bilirubin of 36.2 g/dL, an AST of 57 U/L, ALT of 93 U/L, alkaline phosphatase of 224 U/L, total protein of 9.1 g/dL (6.3–8.2), and IgG of 669 mg/dL (751—1,560). The hepatitis viral antibodies including HAV-IgM, HB core-IgM, HBS-AG, HBV core-AB IgG, HIV-1 AB, HDV-AG as well as HCV-RNA, and HBV-DNA by polymerase chain reaction were negative. The ceruloplasmin was 76 mg/dL. Smooth muscle, antinuclear, myeloperoxidase, and LKM antibodies were negative. Alpha-fetoprotein was normal. A hepatitis A IgG-AB was positive. A 24-h urinary copper was 166 μg/dL. A urinalysis did not reveal proteinuria or hematuria. The rest of his lab reports are summarized in Table.
The patient was hospitalized for one day and discharged on oral ursodeoxycholic acid at 600 mg twice daily and hydroxyzine at 25 mg three times daily to be used as needed for pruritus. Two weeks later, he presented to the hospital because of vomiting and unrelenting skin itching. He was hypertensive with a blood pressure of 189/86 mmHg, and the use of metoprolol at a dose of 50 mg twice daily normalized his blood pressure.
A liver biopsy showed features of marked intrahepatic cholestasis, mild portal inflammation consisting predominantly of lymphocytes, foci of lobular inflammation with balloon degeneration, mild Kupffer cell iron deposition and pericellular fibrosis. There was no evidence of granulomas, peliosis, hepatic rosettes, portal fibrosis, or bile duct injury (Fig. 1). The hepatic iron index was 1.19. An a**ominal ultrasound showed mild liver enlargement at 18 cm. The gallbladder and bile duct were normal. The kidneys were slightly echogenic. The CT scan of the a**omen with IV and oral contrast did not show any liver lesion, ascites, or biliary obstruction. A kidney biopsy showed interstitial edema containing a mild lymphohistiocytic infiltrate with numerous esoinophils. An immunofluoresecence stain showed diffuse granular mesangial staining for IgA (2+) (Fig. 2). After 1 wk of hospitalization, the patient was discharged and readmitted 4 days later because of rectal bleeding and a hemoglobin level of 7.9 gm/dL with an MCV of 89 fL. The upper and lower gastrointestinal endoscopies did not reveal any varices. After receiving 2 units of packed red blood cells, his hemoglobin increased to 9.4 g/dL and he was discharged home. Two wk later, he followed up in the outpatient clinic, feeling better without any itching and near-normalization of his lab reports including both kidney and liver function.
Zero V
Well-known member
Worth doing considering how many people are not only using superdrol, but stacking it with other methyls....
Asking for it.