Thanks I'll PM.
The one thing that concerns me,apart from the prostate risk, is the long term effects of SERMs.
The Chinese medicine, basically could a Chinese Yan medicine do better than DTHC for PCT? Very possibly and in the hands of a good Chinese doctor very probably.
No one disputes that Indian medicine has made a MASSIVE impact on supplements, e.g. USP Labs, such as PowerFull ( the idea originates from Mucana puriens), Tribulus Indian (?), Cissus for certain ... perhaps even Anabolic Pump carries Indian medicine: thats their big sellers, PowerFull, Prime, Super Cissus, perhaps Anabolic Pump. Chinese medicine is much systematic and complicated IMO than traditional Indian.
Havn't use DTHC so can't comment. The ingredient list looks like everything (and quite expensive). Is it really better than any other testo booster?
It doesn't need to generate aggression.btw I don't think chinese yan medicine will usually bring you agressiveness though.
This is good advice. Never thought about it like that.A 100g pack of turmeric powder is just 30p in indian spice shop,
Thanks!Tauroursodeoxycholic acid (TUDCA) from China,
That's how this busniess go....
I read the study that Mucan puriens worked better than L-dopa for Parkinson's. Its probably other compounds which are inhibiting its breakdown in the bloodstream (dopamine can't cross the blood-brain barrier, L-dopa can). You can't buy the dopamine decarboxylase inhibitor in the US even on script, green tea might do this (APPNUT seem to think so). If I remember the Parkinson's drug is Sinemet (sp?), which combines L-dopa and the DDI.
The reason DDI can't be bought by itself is if you combined it with lots of e.g. 5HTP, it can be fatal (serotonin syndrome).
Don't think that DHEA is a big libido boost - for older guys it could be. I suspect its other stuff in the yam, but dunno.
Rhodiola is suspected to be a MAOI, presumably B. To my knowledge it was never proven.
Didn't know green tea was MAOI. It can't be strong if so because it would elevate the effect from PEA. I think the EGCG is inhibiting DDC in the blood stream but the only study I saw was in vitro. If think this is the basis to HGHUp: its L-dopa and green tea extract combo.
If that's the case then HGHup is really overprice....
wait, let me check the ingredients...
Chlorophytum borivilanium (75% extract)
I honestly don't know what the above stuff is or what it does, so I can't comment. Oh I see its Safed Musli. Okay, Indian libido booster. Never tried it ... maybe I have if its in PowerFull.
Alot depends on the quality and APPNUT has a high reputation for quality. Also the tea extraction process if they extract the "putative" DDCi at high purity then we are also paying for the R&D, which is what you pay for with USBlab products such as Prime.
HGHUP does have a good reputation. It looks a well thought out designer, so I guess the answer is what's it worth? I am surprised they haven't put zinc in there, magnesium makes sense (sedation).
IGF-2 is another APPNUT product with a good reputation.
Syst Biol Reprod Med. 2008 Jul-Aug;54(4-5):185-95.
Plants used in Chinese medicine for the treatment of male infertility possess antioxidant and anti-oestrogenic activity.
Tempest HG, Homa ST, Routledge EJ, Garner A, Zhai XP, Griffin DK.
Department of Biosciences, Canterbury, Kent, University of Kent, UK. [email protected]
Abstract
In this study Chinese herbs commonly used in the treatment of male infertility were investigated for relevant biochemical activity. Male factor infertility predominantly arises via barriers to, or defects in, spermatogenesis. The process of spermatogenesis is under strict endocrine control; in addition oxidative stress has been implicated in male infertility with significant levels of reactive oxygen species detected in 25% of infertile males. A total of 37 individual herbs and seven herb decoctions used in the treatment of male factor infertility were therefore tested for endocrine activity using a recombinant yeast based assay and antioxidant activity using the FRAP (ferric reducing antioxidant potential) assay. Individual herbs tested did not show androgenic properties, 20 showed strong and 10 weak anti-oestrogenic activity (per g of dried herb tamoxifen equivalents ranged from 1.18-1280.66 mg and 0.06-0.98 mg, respectively). Oestrogenic responses were elicited for two herbs (85.30-550 microg oestradiol equivalents/g dried herb), with seven and three herbs exhibiting a strong or weak anti-androgenic response (per g of dried herb DHT equivalents ranged from 1.54-66.78 mg and 0.17-0.32 mg), respectively. Of these 37 herbs, strong (15 herbs), intermediate (7 herbs) and weak/no (15 herbs) antioxidant activity was detected (ranging from 0.912-1.26; 0.6-0.88 and 0-0.468 microg ascorbate equivalent/mg dried herb, respectively). The seven decoctions (previously used to treat patients) tested elicited strong (5 herbs) and weak (2 herbs) anti-oestrogenic responses (per g of dried herb tamoxifen equivalents ranged from 1.14-13.23 mg and 0.22-0.26 mg, respectively), but not oestrogenic, androgenic nor anti-androgenic, consistent with their individual composition. With regard to antioxidant activity the following responses were recorded: three strong, three intermediate and one weak (ranging from 1.02-1.2; 0.72-0.76 and 0.44 microg ascorbate equivalent/mg dried herb, respectively). The prospects for introducing Chinese herbal treatments into the Western-based medicine are discussed.
PMID: 18942026
This looks poor English. They cannot possibly mean that 1g of herb provides the same activity as 1.2g of tamoxifen? Apart from the toxicity that would give ZERO estrogens and in itself must make the patient very ill.20 showed strong and 10 weak anti-oestrogenic activity (per g of dried herb tamoxifen equivalents ranged from 1.18-1280.66 mg and 0.06-0.98 mg, respectively).
I have tried Chinese foxglove and it had a very noticeable energy effect.
Would like to hear Narraboth's view. I presume this gets put into a larger formula in the same way Chinese foxglove does.
However..
This looks poor English. They cannot possibly mean that 1g of herb provides the same activity as 1.2g of tamoxifen? Apart from the toxicity that would give ZERO estrogens and in itself must make the patient very ill.
Increasing dopamine levels (l-dopa) is linked with increasing hGH, particularly whilst sleeping, but I don't think the mechanism is understood.
@narraboth: Thanks for the recommendation. I'm currently dieting so I think 黃柏 would work nicely.
@Matthias: According to the study, 1g of the the phellodendrone shows an equivalent anti-estrogen response as 1280mg of nolva. Pretty ridiculous.
I have the full-text if either of you would like to see it. Just upped it to rapidshare.
Its got to be a mistake because the stuff would be almost lethal (and thats not a joke), more like Deadly NightShade than Chinese medicine. You'd either be cured of cancer or plagued by it.@Matthias: According to the study, 1g of the the phellodendrone shows an equivalent anti-estrogen response as 1280mg of nolva. Pretty ridiculous.
That is a good point but whilst the efficiency will be much lower the principle should still apply: Parkinson's Sinemet therapy is oral and this is where lack of dopamine means critical health problems.I think that l-dopa /hGH study was base on IV rather than oral route? any study confirm the effect on ORAL l-dopa intake?
Its got to be a mistake because the stuff would be almost lethal (and thats not a joke), more like Deadly NightShade than Chinese medicine. You'd either be cured of cancer or plagued by it.
That is a good point but whilst the efficiency will be much lower the principle should still apply: Parkinson's Sinemet therapy is oral and this is where lack of dopamine means critical health problems.
1. I think I might read that paper next week to see how could this happen... if it's really a mistake then the author, the supervisor, the editor all missed it, that is bad science.
too much dopamine cause addiction.... not a very friendly thing to play with.
Lack dopamine cause health problem, too much dopamine cause addiction.... not a very friendly thing to play with.
We have a publication called "The Beano", which is a child's comic starring "Dennis the Menace" and has been in print for well over 30 years. Well if its true then the herb is toxic at normal dosages.I doubt it was the mistake. The journal it comes from is reputable and has been in print for over 30 years.
Well if its true then the herb is toxic at normal dosages.
The easiest way to do this is to buy Phellodrendron Bark - huáng bò (黄檗) / huáng bǎi (黃柏) and see how I respond to it.
If okay I'll look at 壯陽丸 and 片 and 黃柏 / 地黃
With Tamoxifen at least you know the dosages, heavy dosages, side effects, risks and what to look out for if things go wrong. With Phellodrendron Bark I've no idea. I am going to need blood work to be sure this is safe. The journal has an impact of 3.7 which is reputable and specializes in reproductive medicine.
Thats interesting because you'd have thought it would have the opposite effect.due to Yin Deficienc
Btw, bought about 100g of phellodendron. Gonna try it tomorrow.
Let us know how it goes.
Sketchy Yellow Powder:
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I tried 3g last night. The ladies at the pharmacy said to boil it, but the stove in my building wasn't working again...that's china for ya. So I just put the 3g in a cup with some water and microwaved it for 2.5 min. Then I strained it and put it in a plasic container to chill in the freezer. When it was cool, I chugged it. Not pleasant, but not too terrible either.
This stuff knocked me out. I suspect it was the berberine in it that tanked my already low blood sugar.
I've been on the velocity diet for a little over a week now, and my bowels don't seem to be "moving" like they used to. I definately noticed the mild laxative effect of this herb. If you take too much, I'm pretty sure you'd be spending the day on the toliet regretting doing so.
The next day I looked a lot "drier," despite a less than stellar water intake the day before. A few of my joints have been hurting as well, but I think that it is only a coincidence.
I will play around with the dosing a bit and maybe spread out the 3g through-out the day. Not sure if this is a viable option considering the lack of carbs in my diet and how strongly it effects my blood sugar.
Thats interesting because you'd have thought it would have the opposite effect.
Geee... this stuff is complicated. Its obviously doing much more than estrogen modulation. Its difficult to get your head around Chinese medicine because you'd look at all the stuff its doing and wonder how are they connected?
Hmm... need to think about this before commiting.
黃柏 is used to treat joint pain on elders. not sure if it will really cause joint dry.
When I take it, my joints hurt. When I stop taking it, they stop hurting. This correlates to both my past experience with anti-estrogens as well as the literature regarding it's anti-estrogenic activity in-vitro.
When I take it, my joints hurt. When I stop taking it, they stop hurting. This correlates to both my past experience with anti-estrogens as well as the literature regarding it's anti-estrogenic activity in-vitro.
how's your stomach feeling? isn't it to harsh for apetite?
and may I ask.... is that really you in the photo?![]()
After about a week or so of using it I noticed a reduction in appetite. But for me that was a good thing as I am dieting. Unfortunately, I stopped taking it a few days ago b/c of the joint pain.
I don't doubt it is used to treat joint pain in the elderly, but I would guess that it is used in combination with other herbs. I no expert in this area, I'm just going off of my own observations.
Ha ha, no, that is not actually me in the picture.