Found a source selling transdermal clen/yohimbine/sr9009 they also have a bunch of other transdermal compounds like trenavar, MENT, etc. wondering how this compares to the oral forms. does it absorb better? do you avoid some side effects? anyone have any experience fucking around with transdermals?
That sounds like a great combo. PM me your source if you don't mind.
Transdermal absorption is always superior to oral absorption. This is because when you absorb things through your skin it skips first pass metabolism, just like when you inject something. First pass metabolism is how your liver processes drugs that it takes in. When you take something orally, it has to pass through the liver, which breaks it down and makes it less effective (unless you do some trickery with your orals, but that's another subject). When you skip first pass metabolism, it absorbs into your blood stream and does what it's supposed to do, then it passes through the liver after that.
That's why you don't see people taking oral steroids unless they're esterfied or methylated. The liver is too efficient in breaking down these compounds and inactivates them (along with just your general GI tract not helping out here either)
So, you don't avoid the side effects, if anything, you would potentially have
more side effects. But, because transdermal absorption is also localized to where you apply it instead of systematic like when you take it orally, you could potentially have less side effects because it's only being absorbed in that area.
Think of it sort of like dandruff shampoo. The shampoo is only absorbing into your scalp, and although you do get some of the ingredients absorbed through your whole body, you don't get the effect of the shampoo on other areas like your arms or legs. I don't know if that's a good example or not.
How did transdermal tren compare with injectable/oral ? in terms of side effects +efficacy
It's definitely not as potent, but it is a fine way to use it if you're afraid of injecting or don't want all the super negative sides with it.