Anyone have any experience with transdermal steroids/fat burners?

widthbrah

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Found a source selling transdermal clen/yohimbine/sr9009 they also have a bunch of other transdermal compounds like trenavar, MENT, etc. wondering how this compares to the oral forms. does it absorb better? do you avoid some side effects? anyone have any experience fucking around with transdermals?
 
enhanced

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I love all things transdermal.. especially tren and epiandro. The clen/yohimbine sounds interesting.
 
StarScream66

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Found a source selling transdermal clen/yohimbine/sr9009 they also have a bunch of other transdermal compounds like trenavar, MENT, etc. wondering how this compares to the oral forms. does it absorb better? do you avoid some side effects? anyone have any experience fucking around with transdermals?
That sounds like a great combo. PM me your source if you don't mind.

Transdermal absorption is always superior to oral absorption. This is because when you absorb things through your skin it skips first pass metabolism, just like when you inject something. First pass metabolism is how your liver processes drugs that it takes in. When you take something orally, it has to pass through the liver, which breaks it down and makes it less effective (unless you do some trickery with your orals, but that's another subject). When you skip first pass metabolism, it absorbs into your blood stream and does what it's supposed to do, then it passes through the liver after that.

That's why you don't see people taking oral steroids unless they're esterfied or methylated. The liver is too efficient in breaking down these compounds and inactivates them (along with just your general GI tract not helping out here either)

So, you don't avoid the side effects, if anything, you would potentially have more side effects. But, because transdermal absorption is also localized to where you apply it instead of systematic like when you take it orally, you could potentially have less side effects because it's only being absorbed in that area.

Think of it sort of like dandruff shampoo. The shampoo is only absorbing into your scalp, and although you do get some of the ingredients absorbed through your whole body, you don't get the effect of the shampoo on other areas like your arms or legs. I don't know if that's a good example or not.

How did transdermal tren compare with injectable/oral ? in terms of side effects +efficacy
It's definitely not as potent, but it is a fine way to use it if you're afraid of injecting or don't want all the super negative sides with it.
 
Whisky

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I’ve not used it but people were talking highly of clenviserate (td clen plus another fat burner) so I know clen as a TD can be effective. As for any other compound it depends a lot on the molecular weight (I forget what it needs to be under but in a nutshell a compound has been be small enough to pass through).

due to the sheer ease of application plus improved absorption from skipping the liver I would assume that if it were possible then nearly every oral or injectable out there would already have a TD version (I mean most people would rather use TD than inject or impact their liver more with an oral right).

so my guess is that some of these compounds won’t be well absorbed unless we are looking at brand new tech that’s somehow got over the previous issues?
 
delsolrob

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IMO the major benefit of a clen TD is the slow release it offers. taking oral doses of clen in the amounts most take can leave you feeling extremely jittery, td will help slowly release the clen into your system so you don't get hit with the dose all at once...leaves it feeling a bit more like a smooth transition instead of getting smacked in the face.
 
StarScream66

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I’ve not used it but people were talking highly of clenviserate (td clen plus another fat burner) so I know clen as a TD can be effective. As for any other compound it depends a lot on the molecular weight (I forget what it needs to be under but in a nutshell a compound has been be small enough to pass through).

due to the sheer ease of application plus improved absorption from skipping the liver I would assume that if it were possible then nearly every oral or injectable out there would already have a TD version (I mean most people would rather use TD than inject or impact their liver more with an oral right).

so my guess is that some of these compounds won’t be well absorbed unless we are looking at brand new tech that’s somehow got over the previous issues?
The MW needs to be in the 300-500 range to be absorbed through the dermis. Clen's MW is around 277 so it should be fine for TD absorption.

There are also countless threads with feedback about the "clenviserate" combo on this forum, including a massive one,so I would recommend OP checking it.

IMO the major benefit of a clen TD is the slow release it offers. taking oral doses of clen in the amounts most take can leave you feeling extremely jittery, td will help slowly release the clen into your system so you don't get hit with the dose all at once...leaves it feeling a bit more like a smooth transition instead of getting smacked in the face.
Well, the half life of Clen is ~34 hours, but absorption through the skin would probably lower that and only put it in the local area you're trying to lose fat from, which in theory should reduce systematic side effects of the drug.

An alternative, which would be my choice, would be to use Albuterol instead. It's Clen's chemical cousin and works in the same way, but only lasts around 2-4hours in the body.

 

JoePaul39

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IMO the major benefit of a clen TD is the slow release it offers. taking oral doses of clen in the amounts most take can leave you feeling extremely jittery, td will help slowly release the clen into your system so you don't get hit with the dose all at once...leaves it feeling a bit more like a smooth transition instead of getting smacked in the face.
Rob, what is your opinion on absorption ability of transdermal sarms like Rad 140 and LGD 4033 as compared to orals.
 

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