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Anxiety and how to help calm it

Pregnenolone is wonderful for anxiety, but just adding it in can create other issues if it isn't needed. Mainly further elevating e2, which could be part of rascal's issue on 750mg of test. Or it could be unrelated and just throwing stuff in adds variables.
 
I try to use mind tricks on myself and use my anxiety as a positive and use the energy to do something useful instead of let it take me over. Otherwise supplement wise I have had success with NAC, passionflower, omega 3's and a green tea/ chamomile fusion.
 
This a specific recomendation to rascal14 issues or can be used for anyone who suffers from Anxiety?

I cannot be sure for all people but it would help many. If you never feel like having the energy to jump over 7ft fences a few times a day your cortisol is low and therefore all that comes before it: pregnenolone etc.

One thing to note is that only transdermally it would work for anxiety. Its metabolism does not behave the same when taken orally.

It's poor information overall based on what little he actually knows about rascal14's situation.

Lol, touche

Yeah I didn't order any of that, and the waking in a panic went away on its own.

Sounds good

Oh ok, because in fact i already read that pregnenolone can be good in some cases but not so good in another ones. I think theres some cases where Anxiety can be caused for an excess of Cortisol. Anxiety must be one of the most difficult diseases to deal with, diagnose the root of the problem and fix :(

Transdermally it works different from orally. Orally it would likely push your progesterone through the roof but not boost your cortisol and not relieve your anxiety. Weird, I know.

Excess cortisol is a rare thing. You may have very high blood level but it likely goes with a very high corticosterone binding globulin level (CBG) too. The body is taking every measure not run low but genetics and circumstances often get in the way :(

In that case, your test would be low too, or it would be 'normal' but with high SHBG and/or E2 or both. Cells can't take all that test when overall metabolism is low due to low cortisol(along with low thyroid). You can't have different rotational speeds on the either end of the same shaft.

Pregnenolone is wonderful for anxiety, but just adding it in can create other issues if it isn't needed. Mainly further elevating e2, which could be part of rascal's issue on 750mg of test. Or it could be unrelated and just throwing stuff in adds variables.

Transdermal pregnenolone would lower E2 in most. As you make more cortisol, its metabolism goes up and, provided enough thyroid hormones are present, testosterone's metabolism goes up too: you are living in the fast lane, literally. So you end up using your test rather than dumping it to e2 and dht or just increasing SHBG. Some people's genetics makeup favors the dump, others' favors increasing SHBG.

The best thing about pregnenolone, cortisol etc. is that you can top them off without disturbing the negative feedback loop. So A endogenous + B exogenous in most cases equals A+B. Not so for testosterone. A endogenous + B exogenous has you left with B only shortly afterwards.
 
I cannot be sure for all people but it would help many. If you never feel like having the energy to jump over 7ft fences a few times a day your cortisol is low and therefore all that comes before it: pregnenolone etc.

Unless during a Panic Attack or a moment when i feel more anxiety, i always feel really really tired. I sleep 7/8h per night (however i asleep late, not before 1 or 2 am) and my work is not physically demanding (but it´s very mentally demanding). The only moment i feel more energized is when working out but even though, only after 20 or 30 minutes.

Oh and i wake up every morning very drowsy.
 
That was me to a T. If I were you, I'd jump on the transdermal preg and see if you can work with someone to check your thyroid.
 
Ops, i was wrong. What if fact was in higher borderline was FT4.

Here the results:

FT4: 1.68 ng/dL (0.89 - 1.76) / 21.6 pmol/L (11.45 - 22.65)
TSH-H: 1.10 mUI/L (0.55 - 4.78)
FT3: 5.21 pmol/L (2.80 - 7.10)
AC. Anti-Tiroglobulina: <15 U/mL (<60) AC. Anti-Peroxidase Microssomal (TPO) <28 U/mL (<60)

I wasn´t able to translate some names, hope you understand.
 
No Hashimoto, as evidenced by the antibodies, so that's good.

Once you boosted your preg/cortisol you'd get a lot better conversion from T4 to T3. Also, the T4 being that high means you'd have little issue converting the pregnenolone. It could be a very quick change for the better for you.
 
Your words really give me hope... I think i´ll give a try to transdermal pregnenolone.

I saw you previous recommended Nutraplanet combo but i don´t live in USA and here it´s a little hard to get it, my choices are importing from USA (which takes longer and can be seized/taxed by customs) or buy something else.

I had a look at "Prototype Nutrition: Pr Spray", which it´s a little expensive but i can get it in Europe. Do you think it will be ok if i opt for it? but it´s strange i don´t see the produt in their webpage. Maybe it´s some discontinued product.
 
If I had it available, I'd have bought it instead. Go for it!

It says 249mg of Preg per dose/50 sprays. You may find that 100mg a day is enough. That's where I'd start.
 
If I had it available, I'd have bought it instead. Go for it!

It says 249mg of Preg per dose/50 sprays. You may find that 100mg a day is enough. That's where I'd start.

Thanks. Are the mg directly comparable with oral supplementation? I´ve seen some people talking about oral supplementation, saying 50mg is too much and it give some side effects after some days, being the 10mg the recommended initial dosage. But i guess they aren´t comparable, since they work in different ways, i´m correct?
 
I find this quite surprising but people react differently to things. With transdermal application, you don't get the spike you get from taking a capsule and the conversion is not the same. So yes, you are right and would likely experience the same. You could start with 20mg twice daily and see how far up you can go to keep reaping benefits. If you overdose and your cortisol gets high, you'd get really sleepy when your ACTH drops but this is hardly weird or bad. It is just the negative feedback loop telling you back off a bit. I haven't had such an episode yet.
 
Just received some Tianeptine Sodium from Ceretropics. First time trying theirs. Mainly bought it for the acute effects... I'm sure their supply is great stuff, will be finding out tomorrow :) Will likely just be using it here and there until winter arrives, then it'll be daily.
 
I've found taurine + ZMA at night to be calming at night and during the day, assuming it won't interact with Lexapro (ask your doc). Plus they are good for test, performance enhancement, etc.
And I would at least tell him or her if you start adding OTC meds that affect brain chemistry.

Have you tried therapy in conjunction with psychopharmacological approaches? Such as DBT therapy?
 
This might sound stupid to you but it works for me. I have a zen app on my phone and do it every morning before work. As well as since i add yoga into my program i feel more centered. I know you are gonna think its bull**** and stupid i did also when it was suggested to me but i am glad i gave it a chance bc i feel my anxiety lower and centered with my core. If you will look past the cornyness of it and give it a try it will naturally help anxiety.. Hope it helps you bro
 
FWIW, I was using ~1g epiandro for several months in a row and felt great (confident, anxiety free, etc), but since stopping, anxiety is back and social confidence is back down (eye contact and whatnot).
 
FWIW, I was using ~1g epiandro for several months in a row and felt great (confident, anxiety free, etc), but since stopping, anxiety is back and social confidence is back down (eye contact and whatnot).

I was doing some research on epiandro and came across a couple things that worried me. Check this out: Invalid Link Removed
 
I have social anxiety disorder and very insercure even tho i am 5'7" 180 to 190lbs soild muscle and am told am good looking by chicks. Its never hard to pull chicks so... But my insecurities and my social anxiety disorder get in the way. Since starting the zen app and 30 day yoga challenge. I feel more confident i feel better about myself and just a since of well being
 
Has anybody tried Passion flower for anxiety? And if so, what dose?

Passion flower works really well on me for some reason. I know many others that have tried it and they say they don't get anything from it. It's cheap enough to definitely try to see if you respond the way I do from it. I take it when I get home from work or pre-bed. It seems to relax me mentally so I can wind down. For me it mixes well with KMS-66, magnesium and glycine. I have been using Passion flower for the past 2 years at only 350mg. The recommended dose is 700mg but I don't seem to get anything more out of 700mg as I do with the 350mg. The Solar brand Passion flower works best for me over Swanson & Now.
 
anyone ever try SAM-e for anxiety, depression? I've heard nothing but good things about it i take buspar, nortryptiline and magnesium glycinate mostly for GAD but i was thinking about adding this in but its so expensive is the one drawback.
 
anyone ever try SAM-e for anxiety, depression? I've heard nothing but good things about it i take buspar, nortryptiline and magnesium glycinate mostly for GAD but i was thinking about adding this in but its so expensive is the one drawback.

Isn't Buspar very mild? That's what the Doctor prescribed me when I went in for anxiety on Tren. I never actually started it because I dropped then Tren. I couldn't wait a week or so for the medicine to maybe start working. I needed something much stronger for the panic attacks I was having.
 
Passion flower works really well on me for some reason. I know many others that have tried it and they say they don't get anything from it. It's cheap enough to definitely try to see if you respond the way I do from it. I take it when I get home from work or pre-bed. It seems to relax me mentally so I can wind down. For me it mixes well with KMS-66, magnesium and glycine. I have been using Passion flower for the past 2 years at only 350mg. The recommended dose is 700mg but I don't seem to get anything more out of 700mg as I do with the 350mg. The Solar brand Passion flower works best for me over Swanson & Now.
That's the brand I bought too. 1 cap is good for mild anxiety, and 2 caps sedated me. I like it quite a bit.
 
Here's a product you can look at. I personally never used but heard from a few it works well.
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Isn't Buspar very mild? That's what the Doctor prescribed me when I went in for anxiety on Tren. I never actually started it because I dropped then Tren. I couldn't wait a week or so for the medicine to maybe start working. I needed something much stronger for the panic attacks I was having.

It does jack sh** for panic attacks, it has to build up in your system so you dont ever actually feel it working like a benzo but for me its been a godsend for my health anxiety it really helps augment the nortriptyline too for overall mood. 30 mg buspar 50 mg nor and zero side effects from both.
ive been on lexapro before and it was the worst i felt weird like an emotionless zombie i had libido problems was gaining fat and had no motivation for anything.
 
anyone ever try SAM-e for anxiety, depression? I've heard nothing but good things about it i take buspar, nortryptiline and magnesium glycinate mostly for GAD but i was thinking about adding this in but its so expensive is the one drawback.

Yes, my wife takes it and it is nothing short of a miracle. She has fairly moderate anxiety and her doc and a client of hers told her to try it before any scripts. It doesn't wipe out anxiety, but makes the things she'd normally be consumed with into very manageable events and allows her to process it much better. Great stuff for PMS as well.
 
Yes, my wife takes it and it is nothing short of a miracle. She has fairly moderate anxiety and her doc and a client of hers told her to try it before any scripts. It doesn't wipe out anxiety, but makes the things she'd normally be consumed with into very manageable events and allows her to process it much better. Great stuff for PMS as well.

how much does she take? its rather expensive and if i dose of 1600mg is needed i dont want to be buying it every 2 weeks lol
 
I´ve read mixed things about SAM-e and Anxiety.

Some claims it´s very good... other claims it makes it worse. Even some people suffering for depression, said they went from depression to anxiety state. If it´s able to turn depression into anxiety... how it will be if we already suffer from anxiety? That´s my fear.
 
I´ve read mixed things about SAM-e and Anxiety.

Some claims it´s very good... other claims it makes it worse. Even some people suffering for depression, said they went from depression to anxiety state. If it´s able to turn depression into anxiety... how it will be if we already suffer from anxiety? That´s my fear.

All depends on the chemical make up of the individuals brain. It's nearly impossible to tell, the best way is to start low on dosage and slowly increase to see how you react. Because for some increase serotonin can cause worsening of symptoms or vica versa, and same with dopamine, then you get into location of the which those are release change the effects and SOOOO much more. Even the most well educated neurologist could not tell you how it would effect your individual brain.
 
anyone ever try SAM-e for anxiety, depression? I've heard nothing but good things about it i take buspar, nortryptiline and magnesium glycinate mostly for GAD but i was thinking about adding this in but its so expensive is the one drawback.

I've tried buspar before but it made me feel high af... I've read great things but it sent me into another reality.
 
I´ve read mixed things about SAM-e and Anxiety.

Some claims it´s very good... other claims it makes it worse. Even some people suffering for depression, said they went from depression to anxiety state. If it´s able to turn depression into anxiety... how it will be if we already suffer from anxiety? That´s my fear.

It all depends on the individual's makeup and how their methylation cycle works. Sam-E isn't for everyone.
 
I've always needed about 1200mg Sam-e daily (enteric coated) to notice effects. I wish I could respond to a lower dose because it can get quite pricey.
 
I've always needed about 1200mg Sam-e daily (enteric coated) to notice effects. I wish I could respond to a lower dose because it can get quite pricey.

Thats what im saying the mark up is so incredibly high on this im going to try 400 and see how it goes though.
 
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