Guest
Guest
Mulletsoldier said:
LOL..I saw that you responded..scary really..
LOL..I saw that you responded..scary really..
Mulletsoldier
Binging on Pure ****ing Rage
Here is a small write-up on Anabolic Pump I did, just to satiate the masses before Jacob completes the final draft. I am sure he will chime in
How Does Anabolic Pump Work To Build Muscle?
Before we delve into this, we should first distinguish how the GLUT group of isoforms operates as it pertains to glucose regulation. There have been 5 functional GLUTs identified, with the GLUT4 isoform being the major-insulin responsive glucose transporter predominantly restricted to striated muscle and adipose. For this first segment, we will focus mainly on striated muscle.
There are three sites of regulation of intracellular glucose uptake in skeletal muscle: glucose delivery to the skeletal muscle cells, surface membrane permeability to glucose (i.e., glucose transport), and flux through intracellular metabolism. The site most pertinent to Anabolic Pump, is the second mentioned. GLUT4, dormant within vesicles of adipose and striated muscle cells, translocates to the plasma membrane of cells in the presence of Insulin as a result of Insulin activating protein cascades. Anabolic Pump exponentially increases the amount of GLUT4 translocation in skeletal muscle cells, causing the membrane to be supraphysiologically permeable to glucose. Thereby greatly increasing the amount of glycogen stored within muscle cell mitochondria.
This process is being undertaken by two mechanisms; the first being PPAR Gamma 2 modulation, which will be discussed below, and a second unknown mechanism.
How Does Anabolic Pump Induce Fat Loss?
Where Anabolic Pump gets very interesting however, is by inhibiting this same insulin-reactive cascading process in adipocytes. In order to understand this, just as above, we must define a key process inherent within Anabolic Pump’s effects. In this case, we must distinguish the PPAR family, specifically PPAR Gamma 2 and its role in the regulation of adipocyte cells. PPAR Gamma 2 is believed to modulate genes within adipose cells that are responsible for the regulation of certain lipid-binding proteins, proteins that bind to fat, basically. Anabolic Pump is inhibiting PPAR Gamma 2 within adipose cells by two mechanisms which, at this point, are unknown.
In much simpler terms, Anabolic Pump preventing inherent survival traits within Adipose cells to bind to FFAs and circulating blood lipids. This prevents the chronic accumulation of adipose cells by removing their survival mechanism. As a result, lipoylsis is induced and FFAs are metabolized into the bloodstream to used as fuel. Conveniently, striated muscle cells will be 'super-charged' so to speak with glycogen, and with a proper diet and training routine these FFAs will most likely not be re-deposited.
How Does Anabolic Pump Work To Build Muscle?
Before we delve into this, we should first distinguish how the GLUT group of isoforms operates as it pertains to glucose regulation. There have been 5 functional GLUTs identified, with the GLUT4 isoform being the major-insulin responsive glucose transporter predominantly restricted to striated muscle and adipose. For this first segment, we will focus mainly on striated muscle.
There are three sites of regulation of intracellular glucose uptake in skeletal muscle: glucose delivery to the skeletal muscle cells, surface membrane permeability to glucose (i.e., glucose transport), and flux through intracellular metabolism. The site most pertinent to Anabolic Pump, is the second mentioned. GLUT4, dormant within vesicles of adipose and striated muscle cells, translocates to the plasma membrane of cells in the presence of Insulin as a result of Insulin activating protein cascades. Anabolic Pump exponentially increases the amount of GLUT4 translocation in skeletal muscle cells, causing the membrane to be supraphysiologically permeable to glucose. Thereby greatly increasing the amount of glycogen stored within muscle cell mitochondria.
This process is being undertaken by two mechanisms; the first being PPAR Gamma 2 modulation, which will be discussed below, and a second unknown mechanism.
How Does Anabolic Pump Induce Fat Loss?
Where Anabolic Pump gets very interesting however, is by inhibiting this same insulin-reactive cascading process in adipocytes. In order to understand this, just as above, we must define a key process inherent within Anabolic Pump’s effects. In this case, we must distinguish the PPAR family, specifically PPAR Gamma 2 and its role in the regulation of adipocyte cells. PPAR Gamma 2 is believed to modulate genes within adipose cells that are responsible for the regulation of certain lipid-binding proteins, proteins that bind to fat, basically. Anabolic Pump is inhibiting PPAR Gamma 2 within adipose cells by two mechanisms which, at this point, are unknown.
In much simpler terms, Anabolic Pump preventing inherent survival traits within Adipose cells to bind to FFAs and circulating blood lipids. This prevents the chronic accumulation of adipose cells by removing their survival mechanism. As a result, lipoylsis is induced and FFAs are metabolized into the bloodstream to used as fuel. Conveniently, striated muscle cells will be 'super-charged' so to speak with glycogen, and with a proper diet and training routine these FFAs will most likely not be re-deposited.
crankchest
New member
Have not seen anything on how many servings per bottle?
does your weight change anything.
does your weight change anything.
nvr2loud
Member
crankchest said:
At the suggested 2-3 caps per day a bottle will last a minimum of 30 days. There are 90 caps per bottle. May need higher dose if real heavy.
As with anything in life. What and how you eat will have an impact on your body and health. It's not going to do you much good if you are eating McDonald's Big Macs all day.
Your current weight whouldn't have an impact on the results you will receive from this product. Just use the AP to it's fullest like with any other supplement by consuming clean foods and a consistant exercise regimen and you will be more than impressed.
gymrat5713
Member
Ziricote said:
Thanks Ziricote for the info for women. Bc check this out. I thought I was sneaky ordering stuff an hidin it from my girlfriend, well she just told me she also ordered 2 bottles bc she's been checking where I'm goin on internet an found this site and she was dyin to buy some too! Now I don't have to make up excuses about where all my money is goin to. Gotta love it
crankchest
New member
Thanks It is nice to see more companys making there products last a full month, I plan to use this with ON pro complex mass gainer and kre alkalyn. 6' 1 180 18% body fat looking to stay 180 but leaner.
crankchest
New member
I don't think I will be to sad if I get bigger, the more muscle the less fat. I will take the mass!!!
Guest
Guest
Shipped but cart not updated. I walked into the PO a few times with 100 packs pre payed and walked past the long lines. I was cursed, stoned and shot with imagination...christmas is great, but christmas at the PO is like hell.
Guest
Guest
yeahright said:
Back at cha:bow28:
GetYaWeightUp
New member
I'm thinking about stacking Anabolic Pump, (1-androsterone and 4AD) both from American Muscle Science and Methyl-E from EST can i get some feedback on this please.
rpen22
Board Sponsor
Um, I think just one or two posts would've done it to get a response. I'm pretty sure you didn't need to ask this eight separate times, in random threads. JMHO.