Agmatine and L-citrulline/L-citrulline DL-malate
- Thread starter Oxsuam
- Start date
mr.cooper69
Legend
I think it is a fantastic idea. I'm sure Dr. Houser will touch on the Arginine -> Citrulline conversion rate and agmatine's effects on it.
dinoiii
Featured Author
I think supplementation with all polyamines is a good one dependent upon the goal and appropriate concentration. Sometimes I do fear that certain proprietary supplements (even those that list doses) are underdosed and people may dismiss a certain compound's usefulness.
In the case of conversion; polyamines all interconvert for the most part...sometimes it is quick, sometimes it is not so quick. Citrulline itself recycles into arginine and offers a more prolonged NO conversion rate. Agmatine's route back to arginine is actually MUCH slower and dependent upon many factors, but the pathway is as follows:
Agmatine --> N-carbamylputrescine --> (putrescine) + citrulline --> arginine
Use of all of these agents modulate different forms of NOS and at different rates (which can more completely be found in the Agmatine thread).
D_
In the case of conversion; polyamines all interconvert for the most part...sometimes it is quick, sometimes it is not so quick. Citrulline itself recycles into arginine and offers a more prolonged NO conversion rate. Agmatine's route back to arginine is actually MUCH slower and dependent upon many factors, but the pathway is as follows:
Agmatine --> N-carbamylputrescine --> (putrescine) + citrulline --> arginine
Use of all of these agents modulate different forms of NOS and at different rates (which can more completely be found in the Agmatine thread).
D_
heavylifter33
Well-known member
So in regards to timing, i've found that agmatine + carbs about 45 minutes before my workout seems to be the sweet spot. When dosing Citrulline we would need to time this much closer to the workout? Semi-empty stomach.