[/FONT]Accutane contains 13-cis-retonoic acid which over time causes cell loss in the hippocampus, the part of the brain that helps with most cognitive short term memory. Without help from the hippocampus, new semantic memories are too weak to be intentionally recalled as a dream.So in theory, accutane would actually cause a severe loss in dream production over long periods of time exposed to the drug. Of course this is just a theory because cell loss in the hippocampus occur after months of use.The hippocampus also an important component of the limbic system which is a group of structures within the rhinencephalon of the brain that are associated with various emotions and feelings such as anger, fear, sexual arousal, pleasure, and sadness. Damage to the hippocampus by 13 cis retinoic acid causes abnormal functions in the limbic system, which causes things like impotence and most importantly depression. This is why accutane and depression are closely related.
Accutane is not a drug to play around with, it alters the the way the brain functions and can cause depression. If you notice an increase in depression or anger while on accutane consider lowering your dose. I myself am on low dose accutane 20 mg/day and this is the most i will ever go on because i do not think its worth the risk to go any higher than that.[FONT=helvetica, arial, sans-serif]