6oxo extreme

Patrick Arnold said:
Everyone who is into supplements should know about resveratrol but apparently they don't. Its the king of supplements IMO, and should be right up there along with vitamins and minerals

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Patrick,
I know your supplement has resveratrol due to this thread, and as I have stated I am currently using the NowFoods brand which is obviously much lighter dosed. The article says for a human to equal the benefits the mice received they would have to drink around 100 glasses of wine. Now my question- I like what I am seeing even with a low dosed supplement, not even comparable to what the mice had- but what would you suspect the result would be if humans used a dosing simliar to what the mice were given? Do you think it will ever be available or affordable? I guess I have to say it would possibly top all my supplement favorites, and its at the top now.
 
I am taking NOW brand too, I am finding my self taking 12 caps a day, which is very expensive.

I wish I could get 6oxo extreme without the 6oxo (I cannot import 6oxo).
 
jasonschaffin said:
Very true, I would love to see the test. But PA usually puts out good products.
As far as ATD v/s 6-OXO isn't it that under the Ergopharm name he won't use ATD as he doesn't think it is DSHEA compliant? Think I remembe that from a long time ago.
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atd and 6oxo are different compounds. Personally i like 6oxo ALOT more.

EDIT: im sorry i guess i read that wrong i know what you mean.
 
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Ok so let me get this straight. In that article listed it says you would need to have 400mg per kilogram of bodyweight. I weigh 229 as of today, so I would need 41.6 grams of this stuff a day?. That seems like a lot!. I can get a bottle of this stuff for really cheap, around $10. Now I am thinking about it,

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So is it worth it since I can get a HUGE discount? I never thought this stuff was that popular or helpful, but now I'm having second thoughts about it reading this thread.
 
well the problem with reservatrol is it is not that bio avialable i have no clue how you can judge which supp is more bioavailable but trans-reservatrol is as good as it gets for us now. (at least affordable wise, i believe there is an even higher grade tho but $$$)
 
T-Bone said:
Ok so let me get this straight. In that article listed it says you would need to have 400mg per kilogram of bodyweight. I weigh 229 as of today, so I would need 41.6 grams of this stuff a day?. That seems like a lot!. I can get a bottle of this stuff for really cheap, around $10. Now I am thinking about it,

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So is it worth it since I can get a HUGE discount? I never thought this stuff was that popular or helpful, but now I'm having second thoughts about it reading this thread.
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So what do you guys think about this supplement I linked?. Would it be a good deal if I could get it for actually $5 a bottle, sorry $10 was wrong. The wife can get me a bottle for five bucks. Should I get a few bottles and take say 10 servings a day?. Is it worth it?
 
Fabulous One said:
Patrick,
I know your supplement has resveratrol due to this thread, and as I have stated I am currently using the NowFoods brand which is obviously much lighter dosed. The article says for a human to equal the benefits the mice received they would have to drink around 100 glasses of wine. Now my question- I like what I am seeing even with a low dosed supplement, not even comparable to what the mice had- but what would you suspect the result would be if humans used a dosing simliar to what the mice were given? Do you think it will ever be available or affordable? I guess I have to say it would possibly top all my supplement favorites, and its at the top now.
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a couple of things. there is a pharmarceutical company called Sirtris pharmaceuticals that is testing some sort of reseveratrol product with greatly enhanced bioavailability. you can google them to find out more, its interestng

as far as regular people go, one of the mice studies used 30mg/kg bodyweight and the positive results were seen. that equals 3 grams per day for a 220 pound man. the testosterone study (below) used 20mg/kg BW which would be 2 grams for day for a 220 lb man

the highest daily dose of 6-oxo extreme provides 1.2 grams a day. that was the most i could put in the product without making it too expensive

trans-Resveratrol, a natural antioxidant from grapes, increases sperm output in healthy rats.Juan ME, González-Pons E, Munuera T, Ballester J, Rodríguez-Gil JE, Planas JM.
Departament de Fisiologia, Facultat de Farmàcia, Universitat de Barcelona, E-08028 Barcelona, Spain.

trans-Resveratrol was reported to have health benefits including anticarcinogenic effects and protection against cardiovascular disease. One of the mechanisms by which it exerts its action is through modulating the estrogen response systems. Because estrogen is involved in male reproductive biology, we investigated the effect of trans-resveratrol on testis and spermatogenesis. Adult male rats were divided into 2 groups. The treated group was administered by gavage 20 mg/(kg . d) of trans-resveratrol suspended in 10 g/L of carboxymethylcellulose for 90 d, whereas the control group received only carboxymethylcellulose during the same period. The relative weight of testes did not differ between the groups. However, the diameter of the seminiferous tubules was significantly reduced from 437.5 +/- 0.1 mum in the controls to 310.9 +/- 0.1 mum in the resveratrol-treated rats. This decrease was accompanied by a significant increase in tubular density, from 3.20 +/- 0.18 in controls to 6.58 +/- 0.18 tubules/mm(2) in the treated group. Moreover, sperm counts were significantly greater in the resveratrol-treated rats (24.8 +/- 3.30 x 10(7)) than in the control group (14.1 +/- 0.80 x 10(7)), but sperm quality did not differ. Serum concentrations of gonadotrophins and testosterone were significantly higher in the resveratrol-treated group. We identified a novel activity of trans-resveratrol. The daily oral administration of this phytochemical to adult male rats enhanced sperm production by stimulating the hypothalamic-pituitary-gonadal axis, without inducing adverse effects.

PMID: 15795430 [PubMed
 
nelix said:
I am taking NOW brand too, I am finding my self taking 12 caps a day, which is very expensive.

I wish I could get 6oxo extreme without the 6oxo (I cannot import 6oxo).
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i keep bugging my business partner to put some of the 50% resveratrol in caps under giant nutrition.

primarily because i got sick of eating the damn powder and stopped taking it for a while
 
pistonpump said:
well the problem with reservatrol is it is not that bio avialable i have no clue how you can judge which supp is more bioavailable but trans-reservatrol is as good as it gets for us now. (at least affordable wise, i believe there is an even higher grade tho but $$$)
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resveratrol is quickly rendered inactive by sulfation and glucuronidation. these are methods your liver uses to make substances water soluble so they may be excreted in the urine

quercetin is an inhibitor of sulfation and it has been shown to increase the bioavailability of resveratrol substantially. piperine is an inhibitor of glucuronidation so it too is advantageous when consumed with resveratrol
 
It's cheap because it's an 8% extract and does not specify if it is TRANS-resveratrol. I would skip.

T-Bone said:
So what do you guys think about this supplement I linked?. Would it be a good deal if I could get it for actually $5 a bottle, sorry $10 was wrong. The wife can get me a bottle for five bucks. Should I get a few bottles and take say 10 servings a day?. Is it worth it?
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If you are 18 with gyno from past mistakes, I would suggest seeing a physician rather than experimenting with supplements that are not exactly clinically proven and tested to provide your desired effects.


Skyblue said:
safe for 18 year olds? if i have mild gyno due to past mistakes perhaps?
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Patrick Arnold said:
resveratrol is quickly rendered inactive by sulfation and glucuronidation. these are methods your liver uses to make substances water soluble so they may be excreted in the urine

quercetin is an inhibitor of sulfation and it has been shown to increase the bioavailability of resveratrol substantially. piperine is an inhibitor of glucuronidation so it too is advantageous when consumed with resveratrol
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wow. good answer. i figured that was why you had it in 6oxo extreme.....sounds like i need to try this stuff one day. Hopefully itll be around for a while.
 
Patrick Arnold said:
i keep bugging my business partner to put some of the 50% resveratrol in caps under giant nutrition.

primarily because i got sick of eating the damn powder and stopped taking it for a while
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Patrick,

Is this the Sirtris brand that you want them to cap? If its not what brand is putting this 50% resveratrol out in powder form?
 
Fabulous One said:
Patrick,

Is this the Sirtris brand that you want them to cap? If its not what brand is putting this 50% resveratrol out in powder form?
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sirtris is not a supplement company. they are a biotech firm. no one in this industry is privy to their formula and it will be a drug not a supplement.

50% resveratrol is avaialable from china
 
Just for the sake of simplicity -

"Some supplement makers claim that only the trans- form matters, and that the cis- form is not useful or perhaps even a bad thing. Other makers simply report total resveratrol content -- or in some cases, just the quantity of an "extract" source, which only contains some percentage of resveratrol.

Unless specified, one has no certainty whther you are getting cis or trans in each of the extracts. Go for the ones that are obvious that they contain TRANS.

Patrick Arnold said:
i think all natural resveratrol is trans. if cis exists it is a very minor percentage
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DeerDeer said:
I'm going 3 weeks at twice a day then finishing the 4th week with either regular 6oxo of doing 1x day extreme. You'll really like it.
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thanks for the great review, decided to try it. just ordered it from nutra.:clap2:
 
DeerDeer said:
Just for the sake of simplicity -

"Some supplement makers claim that only the trans- form matters, and that the cis- form is not useful or perhaps even a bad thing. Other makers simply report total resveratrol content -- or in some cases, just the quantity of an "extract" source, which only contains some percentage of resveratrol.

Unless specified, one has no certainty whther you are getting cis or trans in each of the extracts. Go for the ones that are obvious that they contain TRANS.
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we researched and the plant that reseveratrol is extracted from in china contains about 95% trans, the rest being cis

so its essentially all trans. no need to fret
 
If someone DID have the money....

Would taking 3-AD (two bottles.. to make an 8 week cycle) then following it with 6-OXO Extreme.... then maybe "PCT" (Post Cycle Therapy) from Anabolic Extreme.... sounds good?

Or is that TOO long for elevated "Natural" Testerone levels...?
 
Patrick Arnold said:
we researched and the plant that reseveratrol is extracted from in china contains about 95% trans, the rest being cis

so its essentially all trans. no need to fret
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I wasn't referring to the 6-oxo extreme - it clearly states it is trans resveratrol - namely one of the reasons I was attracted to trying it in the first place.

While flipping through the literature, special emphasis was placed on the trans isomer, as alledgedly cheaper forms are mostly cis or are simply failed to be labelled accordingly by supplement companies. A couple of sources referenced here contian extracts that are not clearly labelled as cis.
 
DeerDeer said:
If it really is trans-resveratrol - it's a steal. I would inquire directly to verify it. 8% is kinda low - how much are you really getting?
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The wife works at a call center so she gets it for herself really cheap. They are not educated on the supplements much, they just pretty much sell stuff that is advertised on informercials and things like that. They get discounts on products for themselves. I really didn't know anything about this product at all till I saw this thread.
 
Try contacting them to find out what it is exactly extractwise. That is a heck of a good price!

T-Bone said:
The wife works at a call center so she gets it for herself really cheap. They are not educated on the supplements much, they just pretty much sell stuff that is advertised on informercials and things like that. They get discounts on products for themselves. I really didn't know anything about this product at all till I saw this thread.
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Patrick Arnold said:
resveratrol is quickly rendered inactive by sulfation and glucuronidation. these are methods your liver uses to make substances water soluble so they may be excreted in the urine

quercetin is an inhibitor of sulfation and it has been shown to increase the bioavailability of resveratrol substantially. piperine is an inhibitor of glucuronidation so it too is advantageous when consumed with resveratrol
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PA,

I came across a site that is claiming to have 95% Trans Res. My question to you is if a proper ratio of Quercetin and Piperine were taken together with it, would it be able to "survive the digestive tract" as some are saying resveratrol alone normally wouldn't?

I was considering a stack like the following:

weeks 1-4: 11 OXO (3-4 caps/day), 6 OXO Xtreme, 1.0-1.5g T-Resveratrol, quercetin & piperine product
weeks 5-8: 6 OXO Xtreme, 1.0-1.5g T-Resveratrol, quercetin & piperine product.

It certainly wouldn't be cheap but all this talk about res has me interested.
 
riseboi said:
PA,

I came across a site that is claiming to have 95% Trans Res. My question to you is if a proper ratio of Quercetin and Piperine were taken together with it, would it be able to "survive the digestive tract" as some are saying resveratrol alone normally wouldn't?

I was considering a stack like the following:

weeks 1-4: 11 OXO (3-4 caps/day), 6 OXO Xtreme, 1.0-1.5g T-Resveratrol, quercetin & piperine product
weeks 5-8: 6 OXO Xtreme, 1.0-1.5g T-Resveratrol, quercetin & piperine product.

It certainly wouldn't be cheap but all this talk about res has me interested.
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Id like to know if that product in question is really 95% trans too....

That cycle looks awesome im sure PA would approve haha:thumbsup:
 
pistonpump said:
Id like to know if that product in question is really 95% trans too....

That cycle looks awesome im sure PA would approve haha:thumbsup:
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lol, yeah I would hope so. :D Whether I add anything to it or not, I'm definately doing a cycle of 11OXO & 6OXO

As fat as the trans-res, I was a bit mistaken. They supposedly have 99%, 98%, and 50%. They also have "CoA"s posted which appear to be legit. I'm no expert on them, though.
 
pistonpump said:
Id like to know if that product in question is really 95% trans too....

That cycle looks awesome im sure PA would approve haha:thumbsup:
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Rise, as you get closer to doing this, I would love to see your exact game plan for dosages as well as hear your goals from it and suspected sides.

This is kind of what I am planning on doing. I would think this would be a leaning stack with some lean muscle gain and few if any sides.

Thoughts?
 
kraftkid said:
DeerDeer, any new thoughts on the 6oxo X???
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So I am almost done with my second week - I had to post while I had the chance as some of the results are remarkable, subjectively at least.

Recomp. Diet still remains clean.

6 oxo extreme 5 pills 2 x day
2 scoops san infusion 3 x day
Cycle support 2x day
Fish Oil 3 x day
Multivitamin
Cissus 2x day

Workout kept simple -

Chest tri
Back bi
Legs shoulders

Again - I am still on a personally regarded well balanced workout.

So let me start off this week's recap by saying that It is about this week (day 10 onward) that I am actually feelign something. I mentioned before that I don't like feeling that I am on something but this seems positive in nature. Let's list some subjective data -

1) Tell ya what, for the last 3 days, I felt stronger. I have noticed that physically, my strenght has slowly been rising, extra rep, extra set here and there - seamlessly.

2) Libido - increased - well above baseline. Another aspect worth mentioning is somethiing that may be regarded by many as too much information but heck, it is certainly worth mentioning. It is something that I feel some may but for this feature alone - load size. I have tried paravol, with somewhat significant results. But I must say, extreme has taken the cake - larger and thicker ejaculations (as reported byt the significant lady friend). I wouldn't have noticed were it not for her - worthy of report

3) I normally have spontaneous woodies through out the day - but I am talking every 2-3 hours, I am half mast. I feel like I am in high school again. I don't like seeing patients knowing that under the white coat there is half wood hiding - thank god for the white coat. Holy awkwardness

4) Lethargy - yep, it's settled in. I can get up not porblem - been feeling a bit on the tired side a significant more than my baseline. I am aiming for 8 solid hours per night - which usually ends up being about 7. The lethargy is EASILY thwarted with a scooop of superpump or a serving of clearshot - which I have used only 2 times this week.

5) I stopped having those 3+ bowel movements every day - seem slike things have settled down. Mag isn't doing it's previous trick anymore.

6) ZMA and back pimples - nothing notbable yet, we'll see what happens.

Overall - a big boost in libido (and all that comes with it, pun intended), strength increasing, pleasant feeling of being "on" something, slight lethargy.

2 more weeks to go - still debating whether to go all 4 weeks at 2 x day dosing, don't know if I want to drop more $$$ just yet. We'll see. That's all for now. If anyhting interesting pops up in the mean time, I will be sure to report it.
 
i just took my 1st dose today. about 30 minutes after taking it had to take a dump. i guess if its the extreme its a good thing, means its working. deerdeer a quick q, if you dont mind. do you see a problem taking rpm/leviathan/incarnate and reset ad while taking 6 oxo extreme? btw you notice any mirror diference yet? thanks.
 
thebigt said:
i just took my 1st dose today. about 30 minutes after taking it had to take a dump. i guess if its the extreme its a good thing, means its working. deerdeer a quick q, if you dont mind. do you see a problem taking rpm/leviathan/incarnate and reset ad while taking 6 oxo extreme? btw you notice any mirror diference yet? thanks.
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I feel as though it would depnd on your goals. I don't know enough about each of the supps and how they would work individually with you solo to really be able to say how they would work stacked. I am so far pleased with the early findings using it in the manner I am. I have no issue with the superpump/cleashot. No experience with leviathan other than a sample that I thought was ok, made me a tad on the jittery side.

I wish I was able to get labs drawn to really see what the test numbers really are. I really have no medical indication to get these drawn.

Oh yes - and one last thing - I wouldn't recommend drinking while on the extreme - I had one glass of wine and felt flushed and buzzed after ONE measly glass. Three usually give me a buzz but this made me feel totally warm and flushed. I'm a cheap date on 6oxext.
 
thanks for quick reply. havent drank in almost 15 years, so no problem there. the thing im most interested in is, if rpm will enhance absorption even more? alot of guys have said that taking rpm on designer roids makes them better, due to increased absorption, got any info on this? also the reset ad is made to increase effects of stims, so i have to wonder if this will also make extreme better. again thanks for the info.
 
I would think that reset ad should be taken separately from a stim such as RPM. I don' tknow about rpm's ability to increase absorption. I would suggest trying the 6oxext solo. Maybe someone else can chime in who has had personal experience addressing oyur question.
 
DeerDeer said:
I would think that reset ad should be taken separately from a stim such as RPM. I don' tknow about rpm's ability to increase absorption. I would suggest trying the 6oxext solo. Maybe someone else can chime in who has had personal experience addressing oyur question.
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appreciate your direct answer. the problem is you're the only one i heard from that is actually taking 6oxo x. you're advice is sound though, i will take the 6oxox seperate from other supps. thanks again.
 
riseboi said:
PA,

I came across a site that is claiming to have 95% Trans Res. My question to you is if a proper ratio of Quercetin and Piperine were taken together with it, would it be able to "survive the digestive tract" as some are saying resveratrol alone normally wouldn't?

I was considering a stack like the following:

weeks 1-4: 11 OXO (3-4 caps/day), 6 OXO Xtreme, 1.0-1.5g T-Resveratrol, quercetin & piperine product
weeks 5-8: 6 OXO Xtreme, 1.0-1.5g T-Resveratrol, quercetin & piperine product.

It certainly wouldn't be cheap but all this talk about res has me interested.
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quercetin and piperine help prevent its deactivation in the liver. that is not the same as breakdown in the digestive tract

i made an estimate as to the amount of quercetin and piperine that would be sufficient

good luck on your cycle
 
riseboi said:
lol, yeah I would hope so. :D Whether I add anything to it or not, I'm definately doing a cycle of 11OXO & 6OXO

As fat as the trans-res, I was a bit mistaken. They supposedly have 99%, 98%, and 50%. They also have "CoA"s posted which appear to be legit. I'm no expert on them, though.
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the resveratrol bulk material on the market today is extracted from the Polygonum Cuspidatum (a plant) and comes from china

it is all standardized for TRANS-resveratrol. not total resveratrol
 
I would think it would make more sense to take the 6-OXO Extreme after the 11-OXO.
PCT supp after hormone.
Maybe during and after, but talk about pricey.
 
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