Recent content by aaronuconn

Cool, and makes sense. Just was something new to me. Didn’t know if these researchers were using something that hadn’t made it to the supplement industry yet

Seems like they’re saying while spermidine may not be what’s driving the benefits, it’s metabolite is. But like you said, it appears to contradict other studies

Haven’t read every word in the study yet, but they do state: “Finally, epidemiological studies that have correlated dietary spermidine intake with biological effects are challenged by our results, as such studies have not considered the variability of presystemic spermidine metabolism and...

High-Dose Spermidine Supplementation Does Not Increase Spermidine Levels in Blood Plasma and Saliva of Healthy Adults: A Randomized Placebo-Controlled Pharmacokinetic and Metabolomic Study “In 12 healthy volunteers, 15 mg/d of spermidine was administered orally, and blood and saliva samples...

@sns8778 just curious if you’ve seen raw material companies offering anserine?

Beta Alanine may support cognitive function (older adults). “Results suggested that BA supplementation can improve cognitive function in older adults whose cognitive function at baseline was at or below normal and possibly reduce depression scores.”...

I think AstraGin would be a great addition. Other than uptake/absorption/bioavailability benefits for Glutamine, AstraGin also may be good for Gut Health. They used 100mg in the study below, so 12.5mg per 5g scoop could work quite well for those supplementing ~30g...

Maybe a better Beta Alanine alternative? I don’t believe I’ve seen anserine before https://www.tandfonline.com/doi/full/10.1080/15502783.2022.2053300

New NIH funded study on 2-HOBA in healthy humans: https://link.springer.com/article/10.1007/s10753-023-01801-w

Yes, there will be… I have no insider information, just hoping to speak it into existence [emoji4]

I think he was referencing the lost time in the gym. But also when I’m sick, my appetite goes to just about nothing so it also makes me under-eat quite a bit. Basically just consume whey and whatever I can get down lol. Obviously that’s not conducive to LBM accrual

So no West Coast Roasting + SNS collab on Mushroom Coffee? Oh man

Does this make Gatorade powder a London Broil?

I’d also like to see more research into potential benefits around anti-aging and telemere lengthening as there seems to be some initial research into carnosine’s role in these things. Think it was either cell culture research or some species that are commonly researched when evaluating potential...

Yeah, similar to Creatine… needs to reach at a saturation point. Limitations in some studies (like a lot of supplement trials) are duration of time and also limited subjects. For whatever it’s worth, I’ve used 6g+ daily for 3-4 months and didn’t find notable benefit from a hypertrophy or...