Epi in Transdermal delivery????

Colden

Nimbus Nutrition Co-Founder
Could anyone explain if there would be any additional benefit to using Epistane in a Transdermal Delivery System? Is this a possibility or would it be a big waste of a good product?
 
Waste of product. The epi is methylated ensuring about 98-99% oral bioavailability, transdermal application would only allow for about 25-30% delivery thru the layer of the dermis(if that assuming the methly doesn't increase the molecular weight to much).
 
Very well stated!!!
 
Waste of product. The epi is methylated ensuring about 98-99% oral bioavailability, transdermal application would only allow for about 25-30% delivery thru the layer of the dermis(if that assuming the methly doesn't increase the molecular weight to much).

Exactly right. You would be losing product!
 
Not to mention that rubbing a DHT-esque product into the skin might not be so great for the complexion.
 
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