I weigh 255lbs at 6 ft,(36in waist, 54 in chest). I played lineman in college for four years and was a cop for 10 years before going back to school so i consider myself in decent shape. I say this not out of selfindulgance, but because bodyfat, especially in a man's mid-section, contains aromatase. The more bodyfat in this area, the more likley T will get converted into E. Decreasing bodyfat is always a good idea.
I take 150 mg of pure DIM and 500mg of TMG in the morning and 150mg of both at night. I just use Vitamin World DIM because i was the only DIM product I could find in my area. The only ingedient is DIM. I'm going to order another product but I want to ask Dr. John what he recommends. Dr. John told me to take DIM and TMG along with Arimidex because my 4-Hydroxyestrodiol. 4-Hydroxyestradiol along with 16e-Hydroxyestrone are harmful estrogen metabolite. Moreover, my liver must be a little clogged because my Total Es were originally high. Since the liver is responsible for excreting hormone metabolites, it would make sense that one needs to have efficient liver function to have a helathy estrogen/testosterone balance. One cannot assume they need to take DIM and TMG unless it is justified by lab results. My case is particular to my results.
Dr. John prescribed Pregnenolone Cream because it is more effective than pills and it has a calming effect (nerves, stress, focus). Also, he indicated that it re-establishes hormonal pathways.