bell1986
Well-known member
I think we all know about creatine and it's endless amounts of benefits. It really is the holy grail of fitness supplements. Thousands of positive studies.
An aspect that alot of people don't seem to really talk about is.... It's effect on the methylation system. The body uses 40% of the overall methylation system to create creatine. Supplementing creatine then frees up this system and can throw things out of whack. Your Sam-E levels will increase after adding in creatine.
For most people this isn't an issue. For people like me with an mthfr defect and especially a slow comt gene it's a nightmare.
Insomnia
Anxiety
Depression
Fatigue
This even comes from 1g doses. I've also tested every type from monohydrate to HCL. All have the same issues.
If your supplementing creatine and notice that your sleep is poor. Your anxiety is heightened. You feel a background uncomfortable stimulation. I would stop it for a couple weeks and assess how you feel.
I would genuinely love to be able to use creatine. I've tried numerous times and even tried to balance out the overmethylation side effects. Glycine/Niacin are both methylation balancers. I can run it for a couple weeks and then my methylation goes crazy. So annoying!
Anyone else unable to supplement creatine?
Anything else able to have similar effects but not tap into the methylation system? I do have D-ribose and Peakatp.
What's the verdict on Peakatp? The science looks good but be good to hear actual people's results.
Also. I have no bad words for creatine. I don't want this to seem negative. Creatine is a miracle supplement. I've read of people curing chronic fatigue to debilitating depression by using creatine so it really is incredible.
Thanks
An aspect that alot of people don't seem to really talk about is.... It's effect on the methylation system. The body uses 40% of the overall methylation system to create creatine. Supplementing creatine then frees up this system and can throw things out of whack. Your Sam-E levels will increase after adding in creatine.
For most people this isn't an issue. For people like me with an mthfr defect and especially a slow comt gene it's a nightmare.
Insomnia
Anxiety
Depression
Fatigue
This even comes from 1g doses. I've also tested every type from monohydrate to HCL. All have the same issues.
If your supplementing creatine and notice that your sleep is poor. Your anxiety is heightened. You feel a background uncomfortable stimulation. I would stop it for a couple weeks and assess how you feel.
I would genuinely love to be able to use creatine. I've tried numerous times and even tried to balance out the overmethylation side effects. Glycine/Niacin are both methylation balancers. I can run it for a couple weeks and then my methylation goes crazy. So annoying!
Anyone else unable to supplement creatine?
Anything else able to have similar effects but not tap into the methylation system? I do have D-ribose and Peakatp.
What's the verdict on Peakatp? The science looks good but be good to hear actual people's results.
Also. I have no bad words for creatine. I don't want this to seem negative. Creatine is a miracle supplement. I've read of people curing chronic fatigue to debilitating depression by using creatine so it really is incredible.
Thanks