some cited studies you can quick google ..sorry im not too knowledge in the area as well lol
The second ingredient in Sustain Alpha is 7,8 Benzoflavone. This neuro-active flavone has the ability to pass the blood brain barrier and block the suppression GnRH release through modulation of the GABAergic receptor complex. (6,7,21-30)
Other research has shown 7,8 benzoflavone to have positive effects on libido due to its aphrodisiac and anxiolytic (anxiety-relieving) effects. (10-13)
References
6. Drug/substance reversal effects of a novel trisubstituted benzoflavone moiety (BZF) isolated from Passiflora incarnata Linn. - a brief perspective
KAMALDEEP DHAWAN et al.
Addiction Biology (December 2003) 8, 379 - 386
7. Prevention of chronic alcohol and nicotine-induced azospermia, sterility and decreased libido, by a novel tri-substituted benzoflavone moiety from Passiflora incarnata Linneaus in healthy male rats.
21. Neuroactive flavonoids interacting with GABAA receptor complex.
F Wang, M Shing, Y Huen, SY Tsang, and H Xue
Curr Drug Targets CNS Neurol Disord, Oct 2005; 4(5): 575-85.
22. Prevention of chronic alcohol and nicotine-induced azospermia, sterility and decreased libido, by a novel tri-substituted benzoflavone moiety from Passiflora incarnata Linneaus in healthy male rats.
K Dhawan and et al.
Life Sci, Nov 2002; 71(26): 3059-69.
23. Passiflora: a review update.
Dhawan K, Dhawan S, Sharma A.
J Ethnopharmacol. 2004 Sep;94(1):1-23. Review.
24. A gamma-aminobutyric acidB agonist reverses the negative feedback effect of testosterone on gonadotropin-releasing hormone and luteinizing hormone secretion in the male sheep.
Endocrinology. 2000 Nov;141(11):3940-5.
25. Drug/substance reversal effects of a novel tri-substituted benzoflavone moiety (BZF) isolated from Passiflora incarnata Linn. – a brief perspective.
Dhawan, et al.
Addiction Biology 379-386
26. Anticonvulsant effects of aerial parts of Passiflora incarnata extract in mice: involvement of benzodiazepine and opioid receptors.
Nassiri-Asl M, Shariati-Rad S, Zamansoltani F.
BMC Complement Altern Med. 2007 Aug 8;7:26.
27. Effects of Dialyzing ³-Aminobutyric Acid Receptor Antagonists into the Medial Preoptic and Arcuate Ventromedial Region on Lutienizing Hormone Release in Male Sheep.
Suzie A, et al.
Biology of Reproduction 58, 1038-1046 (1998)
28. Antiandrogen Microimplants into the Rostal Medial Preoptic Are Decrease ³-Aminobutyric Acidergic Neuronal Activity and Increase Luteinizing Hormone Secretion in the Intact Male Rat.
David R et al.
Endocrinology, Vol. 137 No. 10 (1996)
29. Non-classical estrogen modulation of presynaptic GABA terminals modulates calcium dynamics in gonadotropin-releasing hormone (GnRH) neurons.
Nicola Romano, et al.
Endocrinology, 10.1210/en.2008-0424 (2008)
30. Restoration of the Luteinizing Hormone Surge in Middle-Aged Female Rats by Altering the Balance of GABA and Glutamate Transmission in the Medial Preoptic Area
Genevieve S, et al.
Biol Reprod, Jul 2008; 10.1095/biolreprod.108.069831.