Gyno rebound

Hmm, they either said nolvadex , but meant arimidex, or....

They used nolvadex to fight estrogenic sides, but when they came off the nolva, they still had high estrogen as nolvadex just binds to the tissue and fights off estrogen. AKA, to reduce gyno, but doesn't really decrease circulating levels. When they came off the nolva, they should have been running an AI .

Pretty sure nolva can increase prolactin, so maybe that's another theory

Ill have to watch the podcast
 
Ayegee1503 said:
Heard on a podcast today with Seth feroce ... that you can get gyno rebound from nolvedex... is this true ?
Click to expand...
You can get rebound from anything that causes spikes and tanks of your natural hormone levels. Nolva works by simply blocking estrogen receptors, it does absolutely nothing to combat estrogen production or change levels. simply doesnt allow it to bind to the receptors (in this case specifically in breast tissue, causing gyno). WHen you stop the Nolva, these receptors are once again free and any circulating and newly produced estrogen can then bind, causing gyno (in extreme cases).

Nolva is meant to be used simply to trigger more natural test production by "tricking" the body into thinking it doesnt have enough estrogen (which is created from the natural test) and therefore needs to create more test, which can then be converted (some) to estrogen.

This is the difference between a SERM and an AI. An AI (like arimadex) is meant to directly impact the estrogen levels by binding directly to the aromataze enzymes in your body (which is the one that converts T to E) and simply doesn't allow E to even be created (thus lowering the levels).
 
booneman77 said:
You can get rebound from anything that causes spikes and tanks of your natural hormone levels. Nolva works by simply blocking estrogen receptors, it does absolutely nothing to combat estrogen production or change levels. simply doesnt allow it to bind to the receptors (in this case specifically in breast tissue, causing gyno). WHen you stop the Nolva, these receptors are once again free and any circulating and newly produced estrogen can then bind, causing gyno (in extreme cases).

Nolva is meant to be used simply to trigger more natural test production by "tricking" the body into thinking it doesnt have enough estrogen (which is created from the natural test) and therefore needs to create more test, which can then be converted (some) to estrogen.

This is the difference between a SERM and an AI. An AI (like arimadex) is meant to directly impact the estrogen levels by binding directly to the aromataze enzymes in your body (which is the one that converts T to E) and simply doesn't allow E to even be created (thus lowering the levels).
Click to expand...

Thank you very much brother for that explanation... appreciate it
 
Iwilleattuna said:
Hmm, they either said nolvadex , but meant arimidex, or....

They used nolvadex to fight estrogenic sides, but when they came off the nolva, they still had high estrogen as nolvadex just binds to the tissue and fights off estrogen. AKA, to reduce gyno, but doesn't really decrease circulating levels. When they came off the nolva, they should have been running an AI .

Pretty sure nolva can increase prolactin, so maybe that's another theory

Ill have to watch the podcast
Click to expand...

I found a rat study showing Nolva can increase prolactin, but I've never heard of rebound gyno from Nolva. If you use it in the proper amounts, you should be fine. I've heard of people taking up to 100mg of Nolva to get rid of gyno..

Invalid Link Removed
 
Ayegee1503 said:
Thank you very much brother for that explanation... appreciate it
Click to expand...
its that excess estrogen while being stopped at the receptor creates a high amount of estro, the body will try and raise test at at an alarming rate causing a release of aromatase that is a double whammy so to speak. this is why tapering off the SERM helps to slow that transition time rather than just shutting off the signal when you 20/20/20/20
so..imo its right after the taper on the SERM you start up a little bit of your favorite AI. get through the rough spot right there and things should balance out nicely.
 
xR1pp3Rx said:
its that excess estrogen while being stopped at the receptor creates a high amount of estro, the body will try and raise test at at an alarming rate causing a release of aromatase that is a double whammy so to speak. this is why tapering off the SERM helps to slow that transition time rather than just shutting off the signal when you 20/20/20/20
so..imo its right after the taper on the SERM you start up a little bit of your favorite AI. get through the rough spot right there and things should balance out nicely.
Click to expand...

I like that information thank you
 
xR1pp3Rx said:
its that excess estrogen while being stopped at the receptor creates a high amount of estro, the body will try and raise test at at an alarming rate causing a release of aromatase that is a double whammy so to speak. this is why tapering off the SERM helps to slow that transition time rather than just shutting off the signal when you 20/20/20/20
Click to expand...

Interesting info here I did not know. Should people running Serms on cycle to block estrogen start the tapering down of a Serm after the cycle or on? Also, would trt effect this scenario of the body increasing aromatization from a Serm since the body no longer can create testosterone on it’s own?
 
in scenario one I would personally come off the serm at the end of the cycle for 2-3 weeks depending on the cycle. then start a normal PCT protocol.. my theory would be to let some of that built up estrogen clear out naturally before going to pct. the missing serm for those couple weeks shouldnt creat too much of a problem as your androgen levels will still be high.
in scenario 2 there is no need for PCT as the user artificially keeps their test levels stable. however, i am a little confused, exogenous test can still aromatize if thats what you are asking.
 
xR1pp3Rx said:
in scenario 2 there is no need for PCT as the user artificially keeps their test levels stable. however, i am a little confused, exogenous test can still aromatize if thats what you are asking.
Click to expand...

Basically what I am am asking is this- I am on trt, if I used a Serm on cycle to block estrogen, rather than an AI to stop estrogen (prefer not to use AIs since they are bad for lipids), would gyno estrogen rebound from stopping the Serm at the end of the cycle still be a concern? If so, how could this be prevented? I would think it would be a possibility since all the estrogen when on cycle with the Serm would be building up.
 
JoePaul39 said:
Basically what I am am asking is this- I am on trt, if I used a Serm on cycle to block estrogen, rather than an AI to stop estrogen (prefer not to use AIs since they are bad for lipids), would gyno estrogen rebound from stopping the Serm at the end of the cycle still be a concern? If so, how could this be prevented? I would think it would be a possibility since all the estrogen when on cycle with the Serm would be building up.
Click to expand...
remember.. that unless we are talking about methyl estrogen, the body can excrete the unbound estrogen through normal pathways.. the build up isnt a problem in the prescence of normal test levels. The problems occur when everything gets out of balance.. like when you quit taking gear. when on trt... and you say end of cycle, doesnt mean the same thing right?
 
xR1pp3Rx said:
remember.. that unless we are talking about methyl estrogen, the body can excrete the unbound estrogen through normal pathways.. the build up isnt a problem in the prescence of normal test levels. The problems occur when everything gets out of balance.. like when you quit taking gear. when on trt... and you say end of cycle, doesnt mean the same thing right?
Click to expand...

yeah my understanding of these things would mean that at the end of a blast (when your on trt but running an increased dose for a period of time it’s really a blast rather than a cycle) your still taking test which will convert so the hormonal reaction wouldn’t be anywhere near the same as your body still has test to convert and estrogen from that. When you go from a cycle to pct your producing zero/very little test and therefore the body will convert everything as it has no estrogen at all.

on a blast all you are managing is the excess levels from the increased test dose (or other converting aas) rather than the massive swing from cycling. So tapering off the serm dose as you return to trt dosing should be fairly smooth.

I’ve only really heard of rebound gyno when one runs compounds with no conversion and then cycle off and start producing test which will all convert to compensate.

just my understanding and I’m nowhere near as knowledgeable as ripper or others on this stuff
 
This is what I love about trt...not only does it help you maintain gains, but it also reduces the probability of getting gyno.
 
JoePaul39 said:
This is what I love about trt...not only does it help you maintain gains, but it also reduces the probability of getting gyno.
Click to expand...

the maintaining gains and strength through switching to cruise and blast has blown my mind. Absolutely night and day difference.
 
You must log in or register to reply here.
Back
Top