EP1LOGUE Q&A

xtyler said:
Also, since when lower E2 (-IF- this actually happens) automatically translates into lower libido/poor erections? You have to drive it down to zero and even then there's no guarentee (comes to mind a study on Letrozole, the most powerful Rx AI available, where users got their libido improved).
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Agreed but we all react differently and thats why I recommend bloodwork.
Ep1logue contain solid dose of Vaso-6 and Epicatechin which actually can bring better libido/Erection.
 
xtyler said:
Also, since when lower E2 (-IF- this actually happens) automatically translates into lower libido/poor erections? You have to drive it down to zero and even then there's no guarentee (comes to mind a study on Letrozole, the most powerful Rx AI available, where users got their libido improved).

Letrozole versus testosterone. a single-center pilot study of HIV-infected men who have sex with men on highly active anti-retroviral therapy (HAART) with hypoactive sexual desire disorder and raised estradiol levels.

Richardson D1, Goldmeier D, Frize G, Lamba H, De Souza C, Kocsis A, Scullard G.
Author information
Abstract
INTRODUCTION:
Since the advent of Highly Active Anti-Retroviral Therapy (HAART), men with HIV experience good quality of life and expect to have normal sexual function. However, it appears that men infected with HIV commonly complain of sexual problems. We hypothesized that letrozole, an aromatase inhibitor that inhibits the conversion of testosterone to estradiol, would be beneficial in these men.
AIM:
The aim of this study was to compare the effects of testosterone vs. an aromatase inhibitor, letrazole, in HIV-infected men with raised estradiol and low sexual desire.
METHODS:
Thirteen men who have sex with men on HAART with low sexual desire as well as raised estradiol levels (>120 pmol/L) were randomly allocated to receive either parenteral testosterone (Sustanon 250 intramuscular injection) (N = 6) or letrozole 2.5 mg orally daily (N = 7) for 6 weeks.
MAIN OUTCOME MEASURES:
Sex steroid hormone assays, sex hormone-binding globulin, virological, hematological, and biochemical parameters were measured before and after treatment. Each subject was given the Spector Sexual Desire Inventory and the Depression/Anxiety Stress Scale before and immediately after treatment. Subjects were also asked to estimate the number of actual sexual acts before and after treatment. Results. Inventory data showed a rise in dyadic desire in both treatment arms. Mean actual sexual acts rose from 0.43 to 1.29 for the letrozole group. Luteinizing hormone increased in seven of seven men on letrozole. Serum testosterone increased in seven of seven men on letrozole. There were no adverse events from either medication.

FYI, 2.5mg Letro a day makes your E2 UNDETECTABLE, yet their sexual activity tripled. Stop looking at this whole topic as black/white. That's not how it works.
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Good points and agree but Urolithin B Is not Letrozole and we actually dont know 100% how it really works. (Not even scientists who ran studies on Urolithin B).

I just hope people give a fair chance to Ep1logue and not stacking it with 100s of other supps
 
xtyler said:
Also, since when lower E2 (-IF- this actually happens) automatically translates into lower libido/poor erections? You have to drive it down to zero and even then there's no guarentee (comes to mind a study on Letrozole, the most powerful Rx AI available, where users got their libido improved).

Letrozole versus testosterone. a single-center pilot study of HIV-infected men who have sex with men on highly active anti-retroviral therapy (HAART) with hypoactive sexual desire disorder and raised estradiol levels.

Richardson D1, Goldmeier D, Frize G, Lamba H, De Souza C, Kocsis A, Scullard G.
Author information
Abstract
INTRODUCTION:
Since the advent of Highly Active Anti-Retroviral Therapy (HAART), men with HIV experience good quality of life and expect to have normal sexual function. However, it appears that men infected with HIV commonly complain of sexual problems. We hypothesized that letrozole, an aromatase inhibitor that inhibits the conversion of testosterone to estradiol, would be beneficial in these men.
AIM:
The aim of this study was to compare the effects of testosterone vs. an aromatase inhibitor, letrazole, in HIV-infected men with raised estradiol and low sexual desire.
METHODS:
Thirteen men who have sex with men on HAART with low sexual desire as well as raised estradiol levels (>120 pmol/L) were randomly allocated to receive either parenteral testosterone (Sustanon 250 intramuscular injection) (N = 6) or letrozole 2.5 mg orally daily (N = 7) for 6 weeks.
MAIN OUTCOME MEASURES:
Sex steroid hormone assays, sex hormone-binding globulin, virological, hematological, and biochemical parameters were measured before and after treatment. Each subject was given the Spector Sexual Desire Inventory and the Depression/Anxiety Stress Scale before and immediately after treatment. Subjects were also asked to estimate the number of actual sexual acts before and after treatment. Results. Inventory data showed a rise in dyadic desire in both treatment arms. Mean actual sexual acts rose from 0.43 to 1.29 for the letrozole group. Luteinizing hormone increased in seven of seven men on letrozole. Serum testosterone increased in seven of seven men on letrozole. There were no adverse events from either medication.

FYI, 2.5mg Letro a day makes your E2 UNDETECTABLE, yet their sexual activity tripled. Stop looking at this whole topic as black/white. That's not how it works.
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In an earlier post you stated that “UroB has some well known aromatase inhibiting properties.” So is OL acknowledging that Ep1logue can cause a reduction in estradiol?
 
slickwillie said:
In an earlier post you stated that “UroB has some well known aromatase inhibiting properties.” So is OL acknowledging that Ep1logue can cause a reduction in estradiol?
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In vitro, sure. Like countless other naturally occurring compounds.

Had it caused a noteworthy effect on E2 in our in-house testing, we would have marketed it as an A.I. too. Nobody likes to sell LESS for no reason.
 
slickwillie said:
In an earlier post you stated that “UroB has some well known aromatase inhibiting properties.” So is OL acknowledging that Ep1logue can cause a reduction in estradiol?
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According to studies, you need more than 150mg Urolithin B daily to get strong AI effects. Thats why I dont understand how people gets lowered libido/Erection and thats why I recommend bloodwork to see whats actually going on
 
Would you guys recommend discontinuing Ep1 for the time being if we are experiencing such negative side effects?
 
I’m on Week 5 of Epilogue which is also Week 5 of PCT. I took the past three days off the gym and ate anything and everything. I was flat and soft by the time I made it to the gym yesterday but the pumps and fullness came back within minutes of lifting. I also had trouble keeping to sixty second rest periods as I was ready to go most sets by the thirty second mark.
 
I am finishing off my second bottle and have been eating in a surplus throughout the 8 weeks....
I am within 1-2 lbs of my starting weight yet waist is slimmer and quads, traps and arms are noticeably larger. I have received many positive comments and some accusations that I am juicing lol

Contrary to some isolated feedback I have experienced no decrease in appetite, libido or energy. In fact, I have had amazing energy & endurance despite sleeping less (self inflicted). Strength is up despite mild joint stiffness. Overall, EP1LOGUE is by far my favourite supp.
 
GNO said:
I am finishing off my second bottle and have been eating in a surplus throughout the 8 weeks....
I am within 1-2 lbs of my starting weight yet waist is slimmer and quads, traps and arms are noticeably larger. I have received many positive comments and some accusations that I am juicing lol

Contrary to some isolated feedback I have experienced no decrease in appetite, libido or energy. In fact, I have had amazing energy & endurance despite sleeping less (self inflicted). Strength is up despite mild joint stiffness. Overall, EP1LOGUE is by far my favourite supp.
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Ok thats all good, but no bloodwork? You a rookie or a pro?? Or dont give a damn from the sounds of it, toxicity report no where? Sorry dont wish burst no bubbles, I have bought all your products Re1gn, KingsBlood, Endure, Ep1.. etc and been a fan.. but im tired of youtube videos you guys just testing damn flavours..back up all your **** with some blood work results..it all goes bit silent when side effects mentioned!
 
00A said:
Ok thats all good, but no bloodwork? You a rookie or a pro?? Or dont give a damn from the sounds of it, toxicity report no where? Sorry dont wish burst no bubbles, I have bought all your products Re1gn, KingsBlood, Endure, Ep1.. etc and been a fan.. but im tired of youtube videos you guys just testing damn flavours..back up all your **** with some blood work results..it all goes bit silent when side effects mentioned!
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Did anyone in OL notice or get decreased estrogen?

No natty supplement should be that hormonal or have such a effect on them. Maybe minor changes
 
00A said:
Ok thats all good, but no bloodwork? You a rookie or a pro?? Or dont give a damn from the sounds of it, toxicity report no where? Sorry dont wish burst no bubbles, I have bought all your products Re1gn, KingsBlood, Endure, Ep1.. etc and been a fan.. but im tired of youtube videos you guys just testing damn flavours..back up all your **** with some blood work results..it all goes bit silent when side effects mentioned!
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Curious how many supplements you use that have bloodwork backing them up....

First of all, I cannot request bloodwork in my country without a serious reason as a doctor needs to authorize it, no private option available.

Even if I did, you have no idea what else I am taking or what medical conditions I may have. Nor do you know when I took the bloodwork anyways and would not likely believe it unless it aligns with your viewpoint. Frankly, 'Id prefer if you took your negative elsewhere....maybe back to a BLR thread.
 
GNO said:
Curious how many supplements you use that have bloodwork backing them up....

First of all, I cannot request bloodwork in my country without a serious reason as a doctor needs to authorize it, no private option available.

Even if I did, you have no idea what else I am taking or what medical conditions I may have. Nor do you know when I took the bloodwork anyways and would not likely believe it unless it aligns with your viewpoint. Frankly, 'Id prefer if you took your negative elsewhere....maybe back to a BLR thread.
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So what about your RnD you not tested properly on a clean individual. Maybe dont have to be you specifically..Wow shocking..
I can get online blood tests from private labs using websites in UK, America that has everything, dont have this ?? Another shocker..

My negativity.. oh wow, thanks for the quick shutdown.. was making a very valid point indeed, as a company you should do proper testing especially on new ingredients. You have even StimX which no one knows what it is, so how anyone even know of side effects of it, just another example..

Each time someone has tried to bring up valid concerns they get shutdown pretty quick..

I guess you just lost a customer, dont worry I want post further incase I really may discourage others from using the product,

End of day, you took my money, you claim to be a peoples company, now I see you dont give a ****, so let the effects speak for themselves..

Good luck everyone..
 
francisco said:
Has anybody experienced negative side effects? I most certainly did. At 3 weeks of usage i began getting headaches, and began feeling uneasy and dizzy. I pretty much had the symptoms of high blood pressure. I discontinued using it and just a couple of days later i felt normal again. I've been lurking here waiting to see if anybody had any issues but so far I've only seen one post. I wanna hear some feedback.
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I have had similar i train fasted and preworkout take 2 Epilogue ,extend perform and ergonine intra workout take endur3. And i was getting alittle dizzy and not feeing well. Left gym early once because of it. I stopped endur3 and felt fine so i tried taking endur3 and stopped ergonine and also felt fine. Tried it all together again and didnt feel well so not sure whats interacting in my case causing it. I am stim sensitive but all of these should be stim free
 
Jbrooks said:
I have had similar i train fasted and preworkout take 2 Epilogue ,extend perform and ergonine intra workout take endur3. And i was getting alittle dizzy and not feeing well. Left gym early once because of it. I stopped endur3 and felt fine so i tried taking endur3 and stopped ergonine and also felt fine. Tried it all together again and didnt feel well so not sure whats interacting in my case causing it. I am stim sensitive but all of these should be stim free
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how long have you been taking the ep1?
its always nice to know to compare to oneself.

i hope things will get cleared up here, its not only one person with possible side effects anymore.
 
Jbrooks said:
I have had similar i train fasted and preworkout take 2 Epilogue ,extend perform and ergonine intra workout take endur3. And i was getting alittle dizzy and not feeing well. Left gym early once because of it. I stopped endur3 and felt fine so i tried taking endur3 and stopped ergonine and also felt fine. Tried it all together again and didnt feel well so not sure whats interacting in my case causing it. I am stim sensitive but all of these should be stim free
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how long have you been taking the ep1?
its always nice to know to compare to oneself.

i hope things will get cleared up here, its not only one person with possible side effects anymore.
 
iamyourfather said:
how long have you been taking the ep1?
its always nice to know to compare to oneself.

i hope things will get cleared up here, its not only one person with possible side effects anymore.
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Ep1logue and endur3 around 2 weeks (oct28) other two have taken for around a yr
 
Jbrooks said:
I have had similar i train fasted and preworkout take 2 Epilogue ,extend perform and ergonine intra workout take endur3. And i was getting alittle dizzy and not feeing well. Left gym early once because of it. I stopped endur3 and felt fine so i tried taking endur3 and stopped ergonine and also felt fine. Tried it all together again and didnt feel well so not sure whats interacting in my case causing it. I am stim sensitive but all of these should be stim free
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AGAIN, you should have checked your blood pressure rather than guessing. Working out fasted + strong vasodilator, I'd tend to believe your BP went too low, not too high.
 
EP1LOGUE Q&A

xtyler said:
AGAIN, you should have checked your blood pressure rather than guessing. Working out fasted + strong vasodilator, I'd tend to believe your BP went too low, not too high.
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I never said it went to high or that it was even Ep1logue as if you read what i wrote In testing different things in the morning I never stopped the Ep1logue but taking one of the other two out stopped it so it was more a combination of the pre and intra supplements.

Since it states to take Ep1lounge on empty stomach not sure how I wouldn’t work out fasted which isn’t an issue as I normally did anyway
 
Jbrooks said:
I never said it went to high or that it was even Ep1logue as if you read what i wrote In testing different things in the morning I never stopped the Ep1logue but taking one of the other two out stopped it so it was more a combination of the pre and intra supplements.

Since it states to take Ep1lounge on empty stomach not sure how I wouldn’t work out fasted which isn’t an issue as I normally did anyway
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My bad, mixed up francisco's post with yours.
BTW you can take Ep1 on empty stomach without working out fasted; wake up, take Ep1, breakfast, lift.
 
Note to self. 2 caps of Ep1logue prior to a high rep dreadlift session can cause nearly debilitating back pumps Might have to cut it to one cap next time. Endurance and recovery was excellent though.
 
jh1 said:
Note to self. 2 caps of Ep1logue prior to a high rep dreadlift session can cause nearly debilitating back pumps Might have to cut it to one cap next time. Endurance and recovery was excellent though.
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Try this trick: do some LIGHT AB Crunches between deadlift sets. Reciprocal inhibition. When the central nervous system sends a message to the agonist muscle (muscle causing movement) to contract, the tension in the antagonist muscle (muscle opposing movement) is inhibited by impulses from motor neurons, and thus must simultaneously relax.
 
xtyler said:
Try this trick: do some LIGHT AB Crunches between deadlift sets. Reciprocal inhibition. When the central nervous system sends a message to the agonist muscle (muscle causing movement) to contract, the tension in the antagonist muscle (muscle opposing movement) is inhibited by impulses from motor neurons, and thus must simultaneously relax.
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Wait you guys actually lift?! I should try that ;)
 
EP1LOGUE Q&A

@OL

is there any problem stacking cardar1ne with ep1logue?

would be during a mini cut, 2-max. 3 weeks; to keep up the endurance.
i think 12 weeks are the max. amount of days you can use the GW save, right? so maybe i would use it till the 2 bottles are empty. havent bought it yet
 
I deal with moderate adrenal fatigue and this product set me back after a week of use so I had to discontinue. Ive tried products containing epicatechin in the past without issue so it must be something else in this. Im sure this is a great product to take under normal circumstances and one Ill get back on once Im healed..but just a heads up to anyone with adrenal issues you may want to get that under control before trying this.
 
JohnnieFreeze said:
I deal with moderate adrenal fatigue and this product set me back after a week of use so I had to discontinue. Ive tried products containing epicatechin in the past without issue so it must be something else in this. Im sure this is a great product to take under normal circumstances and one Ill get back on once Im healed..but just a heads up to anyone with adrenal issues you may want to get that under control before trying this.
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what did it cause in detail? you feel noticeably worse with ep1logue than without it?
 
JohnnieFreeze said:
I deal with moderate adrenal fatigue and this product set me back after a week of use so I had to discontinue. Ive tried products containing epicatechin in the past without issue so it must be something else in this. Im sure this is a great product to take under normal circumstances and one Ill get back on once Im healed..but just a heads up to anyone with adrenal issues you may want to get that under control before trying this.
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I would try to get an actual diagnosis on that. It's generally accepted that "adrenal fatigue" isn't a real thing, so it's probably something else causing your symptoms. And obviously with any underlying conditions, we encourage you to run any supps past your doctor first.
 
carguy123 said:
also how do you know you have adrenal fatigue? Is this a self diagnosis?
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You should also remember that no scientific proof exists to support adrenal fatigue as a true medical condition. "Adrenal fatigue" is a term applied to a collection of nonspecific symptoms, such as body aches, fatigue, nervousness, sleep disturbances and digestive problems. The term was coined by a naturopath.
 
Myrmidon said:
LOL, Ive never seen a supp cause so many different psychosomatic issues. Or maybe Im just lucky.....
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I’m a huge fan of OL. But either everyone is jumping on the bandwagon “this product has some stellar reviews, quick must be giving me sides” or the Uro is causing more hormonal issues than we once expecting

On my second bottle now with no sides but it’s amazing how all these reports make you weary subconsciously. If it actually decreased estrogen in any way my hair would be falling out (guaranteed), sore joints, low libido etc but I am getting NONE of that, it’s actually quite the opposite. Even have a spike in mood

Not bashing OL, but I hope to **** that nothing is suspect in this lol
 
horizons said:
I’m a huge fan of OL. But either everyone is jumping on the bandwagon “this product has some stellar reviews, quick must be giving me sides” or the Uro is causing more hormonal issues than we once expecting

On my second bottle now with no sides but it’s amazing how all these reports make you weary subconsciously. If it actually decreased estrogen in any way my hair would be falling out (guaranteed), sore joints, low libido etc but I am getting NONE of that, it’s actually quite the opposite. Even have a spike in mood

Not bashing OL, but I hope to **** that nothing is suspect in this lol
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Any supplement that has a tangible effect has the potential to have a side effect, with all things we consume (input), there is some kind of reaction which leads to an output. If this didn't occur then every and all supplements or drugs will do nothing. In my experience with all these compounds I have found higher doses of -epi to cause dryness of my joint, even stiffness of muscles etc. Ep1logue have a very high dose of a significantly more absorbable and bio-available (-)-epicatechin (not its conjugates etc like regular (-)-epi) , I know a number of people who are complaining of these sides such as joints and that were stacking Ep1logue with other -epi products.

The overwhelming amount of feedback we are receiving is very positive for the product who are following the dosage instructions.
 
NoAddedHmones said:
Any supplement that has a tangible effect has the potential to have a side effect, with all things we consume (input), there is some kind of reaction which leads to an output. If this didn't occur then every and all supplements or drugs will do nothing. In my experience with all these compounds I have found higher doses of -epi to cause dryness of my joint, even stiffness of muscles etc. Ep1logue have a very high dose of a significantly more absorbable and bio-available (-)-epicatechin (not its conjugates etc like regular (-)-epi) , I know a number of people who are complaining of these sides such as joints and that were stacking Ep1logue with other -epi products.

The overwhelming amount of feedback we are receiving is very positive for the product who are following the dosage instructions.
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11th day with 3 caps daily, no headache,no joint issues or any sides. It definitely did something with my stomach (no appetite at all) first 2-4 days but went away.
 
Second bottle, pumps have stopped, getting more from agmatine pre workout than I was with Ep1logue. No strength gains and starting to get pains behind my legs and a general uneasy feeling like slight anxiety.
Really had high hopes for Ep1logue ️
 
jt75 said:
Second bottle, pumps have stopped, getting more from agmatine pre workout than I was with Ep1logue. No strength gains and starting to get pains behind my legs and a general uneasy feeling like slight anxiety.
Really had high hopes for Ep1logue ️
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Are you in a deficit or surplus? Because there is very little data on Agmatine actually increasing nitric oxide whereas vaso-6 has tons on it. The pains would indicate you aren't recovering or your muscles are actually growing too fast anecdotally speaking, so if your muscles are growing then that is a positive.
 
wasnt there mental side effects from heavy dose of epi1 and uro isnt very much studied just throwing that out there.

iv used ep1c unleashed for years never had any issues so maybe the uro is doing something different?
 
Have just purchased ep1logue, but have seen some feedback today of a few users reporting low estro type sides? Is anyone else having this issue? Slightly concerned with this.
 
horizons said:
I’m a huge fan of OL. But either everyone is jumping on the bandwagon “this product has some stellar reviews, quick must be giving me sides” or the Uro is causing more hormonal issues than we once expecting

On my second bottle now with no sides but it’s amazing how all these reports make you weary subconsciously. If it actually decreased estrogen in any way my hair would be falling out (guaranteed), sore joints, low libido etc but I am getting NONE of that, it’s actually quite the opposite. Even have a spike in mood

Not bashing OL, but I hope to **** that nothing is suspect in this lol
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I can ASSURE you that if 1-2 people started claiming Ep1logue gave them epileptic seizures and priapism episodes lasting 12hrs, within 2 days 30 more people would report the same.
 
xtyler said:
I can ASSURE you that if 1-2 people started claiming Ep1logue gave them epileptic seizures and priapism episodes lasting 12hrs, within 2 days 30 more people would report the same.
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can you give me an answer to my question about the cardar1ne? is it safe to use with the ep1logue? also which dose would you recommend? i wouldnt use it more than 12 weeks straight, dose would may be between 10-20mg, so 2 caps

and b2t: do you say that ep1logue is clearly NOT strong enough to play around with your hormones? what were the results of your or the OL testers blood test after testing the UroB?
 
xtyler said:
I can ASSURE you that if 1-2 people started claiming Ep1logue gave them epileptic seizures and priapism episodes lasting 12hrs, within 2 days 30 more people would report the same.
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Seriously wtf???
Are you honestly saying that if 2 people had epileptic seizures from ANY OL product then 2 days later 30 more people would fraudulently claim they also had epileptic seizures after forking out money for a product they hoped would deliver gains?
That logic is is nonsense dude!
 
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