NutraChem
Active member
I don't know how I missed your response to this - this is awesome.
It really does amaze me how many things are supposed to do this or not do that, in theory, but then in real life they do the opposite.
I would think that transdermal application, at best, gets 30% of the active into your system, and maybe as little as 15%, so at 250 mg of 11-KT per day transdermally, I would think that's between 32-65 mg that actually gets into your system....oral bioavailability doesn't have to be all that high to compete with this. And if you're talking 20% better transdermally, that means that 250 mg is turning into approx. 26-52 mg of of active 11-KT in your system, which is 10-15% bioavailablity...not great, but it would in theory the numbers would add up that way.
I keep my HP33 close at all times, so I can relate to your statistical calculations!
But yeah, it is amazing how variable these things can be. Any scientist who doesn't admit it has more ego that brains, but life is not the perfect equation, lol. People like to cite clinical data, research papers, and stuff like that when they give their spiel, and that's a good start. But you never truly know until you've tested for yourself, and sometimes the results are quite unexpected! This is definitely one of those times that my observed yield surpassed my calculated yield in a way that was blatantly significant.