DHEA

OrangePeellll

New member
Hi, I have been taking 750 mg of DHEA a day and I am losing weight ( current stats: 5'4" 123). I used to need 2,200 calories to maintain now it's closer to 3,100 (with less activity too). I take DHEA for enhanced libido and strength.

Is this normal ? Thanks !
 
Any issues with estrogen or gyno? And how long have you been lifting before you started supplementing DHEA?

Oh and what age are you
 
Bartmac36 said:
Any issues with estrogen or gyno? And how long have you been lifting before you started supplementing DHEA?

Oh and what age are you
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No gyno or estrogen issues (acne is flaring up tho).

Age: 24

Been lifting for 5 months. Lifts at 123 lbs: B: 115 S: 175 DL: 305
 
24 yrs old. 5 months lifting and youre running 750mg of DHEA for libido and strength of all things you could be running???

Did you do any research on DHEA at all? Do you have any underlying medical condition that prompted youto opt for DHEA. Id advice you to get some bloods if you persist on running that dose.
 
ucheoma said:
24 yrs old. 5 months lifting and youre running 750mg of DHEA for libido and strength of all things you could be running???

Did you do any research on DHEA at all? Do you have any underlying medical condition that prompted youto opt for DHEA. Id advice you to get some bloods if you persist on running that dose.
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I agree. There's no reason to even use DHEA at your age unless you have bloods showing suboptimal levels. Doing more harm than good.
 
DHEA has some cool benefits, even for younger users...but that dose is way too high. 100mg/day has clinical studies proving its effectiveness for testosterone and free testosterone enhancement
 
VaughnTrue said:
DHEA has some cool benefits, even for younger users...but that dose is way too high. 100mg/day has clinical studies proving its effectiveness for testosterone and free testosterone enhancement
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im 24 and i used one pump of dermacrine daily as at the dose I read it's not suppressive and had some nice benefits with mood and libido, also made my down there more sensitive which was nice as im one of the "Marathon men" and it fuc-king sucks.
 
YoungBodyBuil said:
im 24 and i used one pump of dermacrine daily as at the dose I read it's not suppressive and had some nice benefits with mood and libido, also made my down there more sensitive which was nice as im one of the "Marathon men" and it fuc-king sucks.
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Dermacrine is the bees knees.
 
I take 25 mg 3-4 times a week for a month then off for a month, no sides. Good increase in libido, good increase in wellbeing, some increase in recovery. It has given some good results...then again I was 19 when u were born
 
Data and medical opinions benefits/risks on DHEA is mixed so caution is advised when taking DHEA. There are a number of side effects associated with DHEA particularly at high levels and a lot of advice ive seen suggest not going above 25mg per day and cycling usage.

Post #13 above is incorrect to suggest Dermacrine is not suppressive at stated dosage. The BPS website advises Dermacrine can be suppressive "Since Dermacrine supplies the body with an outside source of hormones and causes such a significant boost in hormone levels, it can eventually suppress the body's natural hormone production. Therefore, it is recommended that Dermacrine be cycled to avoid inhibition."

From the little research ive done I would certainly recommend a more measured and balanced view re DHEA intake and regular testing to check effect on hormones etc. I struggle to understand why anyone under 30 would want to push against these risks if they have not been diagnosed with clinically low DHEA levels!
 
VaughnTrue said:
DHEA has some cool benefits, even for younger users...but that dose is way too high. 100mg/day has clinical studies proving its effectiveness for testosterone and free testosterone enhancement
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Really?

So it can enhance our OWN production at certain dose?
 
M.I.D said:
Really?

So it can enhance our OWN production at certain dose?
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Abstract
With advancing age, plasma testosterone levels decline, with free testosterone levels declining more significantly than total testosterone. This fall is thought to underlie the development of physical and mental weakness that occurs with advancing age. In addition, vigorous exercise can also lower total and free testosterone levels with the decline greatest in physically untrained men. The purpose of the study was to evaluate the effect of oral DHEA supplementation, a testosterone precursor, on free testosterone in sedentary middle-aged men during recovery from a high-intensity interval training (HIIT) bout of exercise. A randomized, double-blind, placebo-controlled crossover study was conducted for 8 middle-aged participants (aged 49.3 ± 2.4 years) and an additional 8 young control participants (aged 21.4 ± 0.3 years). Each participant received DHEA (50 mg) and placebo on separate occasions one night (12 h) before a 5-session, 2-min cycling exercise (100% VO₂max). While no significant age difference in total testosterone was found, middle-aged participants exhibited significantly lower free testosterone and greater luteinizing hormone (LH) levels than the young control group. Oral DHEA supplementation increased circulating DHEA-S and free testosterone levels well above baseline in the middle-aged group, with no significant effect on total testosterone levels. Total testosterone and DHEA-S dropped significantly until 24 h after HIIT for both age groups, while free testosterone of DHEA-supplemented middle-aged men remained unaffected. These results demonstrate acute oral DHEA supplementation can elevate free testosterone levels in middle-aged men and prevent it from declining during HIIT. Therefore, DHEA supplementation may have significant benefits related to HIIT adaptation.
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This is just one example, lot more out there which show enhanced hormone production in men, with effects becoming more pronounced as the subject increases in age.
 
Im not sure that study concludes that DHEA 'enhances' natural endogenous free test production. Increases free t=levels in middle aged men? Maybe yes. Anyhow no convincing reason even here for young people to supplement DHEA and not above 50mg
 
ucheoma said:
Im not sure that study concludes that DHEA 'enhances' natural endogenous free test production. Increases free t=levels in middle aged men? Maybe yes. Anyhow no convincing reason even here for young people to supplement DHEA and not above 50mg
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I am not claiming there is significant evidence for young people to use it, thus why I stated:

with effects becoming more pronounced as the subject increases in age.
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that said...there is some great info on DHEA out there:


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Results
They saw that the interval training had no noticeable effect on the men's free testosterone level. But DHEA supplementation raised the testosterone level in all of the men.

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The second figure above shows that DHEA had hardly any effect on the cortisol level.

But DHEA did have an effect on the free testosterone:cortisol ratio. This rose, which is good news. The higher the ratio, the more easily the body recovers from physical exertion and builds up muscle mass. At least, that's what you'd expect. Whether this actually happened in the test subjects the researchers didn't measure.

Conclusion
So interval training doesn't affect the concentration of free testosterone the Taiwanese write. "More importantly, we provide convincing evidence that oral DHEA administration can rapidly raise the free testosterone levels of middle-aged men to levels comparable to that of young men, and this increase is well maintained after acute high-intensity interval training."
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Note, this study helped older users MORE, however significantly raised young users free testosterone levels by ~100% as compared to placebo.
 
ucheoma said:
Data and medical opinions benefits/risks on DHEA is mixed so caution is advised when taking DHEA. There are a number of side effects associated with DHEA particularly at high levels and a lot of advice ive seen suggest not going above 25mg per day and cycling usage.

Post #13 above is incorrect to suggest Dermacrine is not suppressive at stated dosage. The BPS website advises Dermacrine can be suppressive "Since Dermacrine supplies the body with an outside source of hormones and causes such a significant boost in hormone levels, it can eventually suppress the body's natural hormone production. Therefore, it is recommended that Dermacrine be cycled to avoid inhibition."

From the little research ive done I would certainly recommend a more measured and balanced view re DHEA intake and regular testing to check effect on hormones etc. I struggle to understand why anyone under 30 would want to push against these risks if they have not been diagnosed with clinically low DHEA levels!
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They said that based off of their recommended doses.............. they recommend a MINIMUM of 3-4 doses for effectiveness...

3x72= 216mg DHEA
4x72=288mg DHEA

So 216mg-288mg of something hormonal? No Sh1t that's suppressive. But if you take a clinically studied dose (clinical studies show safety and ethicacy all the way up to 100mg daily) then you should reap the benefits with either no decrease in endogenous hormone or even a marginal increase. I was currently taking 1 pump daily THAT'S IT but had to stop due to an upcoming log. However i took 1 pump daily which is
72 mg DHEA
36mg Resveratrol(WIll boost T levels as it's a fairly potent AI with a host of other health benefits)
36mg 7,8 Benzoflavone (Will boost T levels due to being an AI)
18mg Pregnenolone (this will help you feel more awake due to pregnenolone helping adrenals)
9mg chrysin( Transdermal chrysin is substantially more effective than oral and has much stronger ai properties transdermally)

So if we look at the dosing of each ingredient WITH ONLY 1 PUMP it could prove to be a very nice mild health tonic that can improve daily life SAFELY without negatively impact endogenous production and infact helping it, there are studies that showing in younger men 50mg DHEA has POSITIVE effects.

SO yes the company for legality reasons will OF COURSE say use carefully can be suppressive, but that's just to be safe AND BASED OFF THE RECOMENDED DOSING GUIDELINES. Which is 3-5 pumps depending on weight. Im 180 pounds which is around the 4 pump area.

4 pumps equals 288mg DHEA would that be suppressive? Sure, 100%.


But I was taking 1 pump daily and felt great.
 
At least 2 gram dhea you must take every day because under that dose you will have no effect, and buy brand new collection of bra for boobies. They will grow like nothing else.
 
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After 6 months of continuous use NO ADVERSE EFFECTS were noticed. 0, zilche. At a full 100mg dosage, while decreasing fat mass and increasing mental health. So let's say you're younger and since your dhea levels would be on the higher end your body will convert the extra DHEA to sex hormones, since dermacrine has built in AI, it'll make conversion to estrogen minimal, therefore it should mainly be converting to testosterone/ DHT which is amazing for males of ANY age especially the increased T:E and T:C ratios. With only 72mg and it being a widely studied controlled dose, how can you go wrong?
 
They also said in the study that testosterone levels WERE NOT significantly altered due to the DHEA being able to convert to multiple hormones, therefore if the testosterone increases are marginal at best according to many clinical studies, how would it shut down T production. NOW REMEMBER, im talking only ONE PUMP of dermacrine, not the production companies recommended dose. Also Dermacrine is much more that just DHEA the 3 AI in it should help elevate T levels while dermacrine increases sexual prowess and mental acuity. So with a controlled dose i believe anyone can benefit.
 
M.I.D said:
Could you run that along with say viron, letrone etc to increase benefit?
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Letrone I'd keep at 1 cap ED it's a VERY strong AI, I got rebound about 6 days after stopping, my fault though I didn't taper it down like what's recommended, I was testing to see if it's suicidal. It's not but it's very strong and has tons of benefits. Lj100 and boron can be stacked with anything, I love Viron great t booster.
 
gigante35 said:
At least 2 gram dhea you must take every day because under that dose you will have no effect, and buy brand new collection of bra for boobies. They will grow like nothing else.
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What? Under 2G DHEA will have no effect but not taking that much DHEA will make men need bras for boobs? Uh.......???
 
YoungBodyBuil said:
Letrone I'd keep at 1 cap ED it's a VERY strong AI, I got rebound about 6 days after stopping, my fault though I didn't taper it down like what's recommended, I was testing to see if it's suicidal. It's not but it's very strong and has tons of benefits. Lj100 and boron can be stacked with anything, I love Viron great t booster.
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could move from letrone onto exotherm I suppose??
 
YoungBodyBuil said:
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After 6 months of continuous use NO ADVERSE EFFECTS were noticed. 0, zilche. At a full 100mg dosage, while decreasing fat mass and increasing mental health. So let's say you're younger and since your dhea levels would be on the higher end your body will convert the extra DHEA to sex hormones, since dermacrine has built in AI, it'll make conversion to estrogen minimal, therefore it should mainly be converting to testosterone/ DHT which is amazing for males of ANY age especially the increased T:E and T:C ratios. With only 72mg and it being a widely studied controlled dose, how can you go wrong?
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For those who dont want to read the study here's the conclusion they were able to extrapolate from the concurrent use of 100mg for 6 months on both men and women.

CONCLUSIONS: A daily oral 100 mg dose of DHEA for 6 months resulted in elevation of circulating DHEA and DS concentrations and the DS/cortisol ratio. Biotransformation to potent androgens near and slightly above the range of their younger counterparts occurred in women with no detectable change in men. Given this hormonal milieu, an increase in serum IGF-I levels was observed in both genders but dimorphic responses were evident in fat body mass and muscle strength in favour of men. These differences in response to DHEA administration may reflect a gender specific response to DHEA and/or the presence of confounding factor(s) in women such as oestrogen replacement therapy.
 
Its generally known that DHEA is a very weak test booster. To get appreciable levels of test increases you have to resort to megadosing similar to OPs 750 mg dose. This comes with attendant increases in other hormones including E and progesterone. If you're over 40 the data seems to be more supportive on replacement benefits from using DHEA as serum DHEA declines with age. Even then the common consensus on dosage seems to be 25mg - 50mg. Ray Sahelian thinks even 25mg ED may be too high! 100mg per day for 6 months may appear safe, for over 40s that is, but then id would like to see data on what happens to endogenous test production after 6 months. The study quoted in post#24 says nothing of this therefore we don't know what the longer term risks even at 100mg. Bottom-line for me is I cant see any compelling reason for under 40s to take this. If you want something for general well being and health then Ashwagandha beats DHEA hands down in terms of health benefits and safety profile. Risks of suppression, increased estrogen, e just to get marginal increases in T levels don't stack up for me

Below are some quotes from Examine.com. The data on DHEA is not black and white but any positives are very unconvincing unless you're 40+ and the one word I would associate with DHEA is 'unreliable'

There appears to be an increase in testosterone following DHEA supplementation, but the vast majority of literature is in menopausal women (where testosterone contributes to libido). There is variability in the results, and DHEA is unreliable in increasing testosterone, but this unreliability extends to all demographics and subjects (with limited evidence of DHEA increasing testosterone in all studies including youthful athletes, which are less studied

Supplementation of DHEA appears to be effective in persons over 40 in the dosage range of 25-50mg, while prolonged usage of 100mg appears to be safe in this demographic. While the usage of DHEA in young persons for the purpose of testosterone enhancement is not clear, it tends to be used at 200mg for this purpose.
 
I would be wary of overgeneralised deductions from the Taiwanese study as per the 100% test increase in young people compared to placebo. If this had any degree of credibility DHEA would have become a standard product of choice in the bb world. For one thing the methodology is questionable to be polite. One dose the night before and the second morning of the interval training? How can you reliably impute changes to test levels based on 2 doses only?Secondly if you look at the chart that effect is an outlier and not replicated across the duration studied. Finally its one study. The ergo log article itself says previous studies on benefits in young resistance trained athletes have been overwhelmingly disappointing. I would treat any contrarian finding from the one taiwanese study with a degree of scepticism.
 
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