Thanks for the response Danes. I still feel that to know for sure we should see a study that shows that PA increases mTOR by ~600% when taken initially, and continues to increase it by ~600% with daily use 4-6 months later. I'm not saying it does or doesn't, other than that the body tends to adapt to most things with time. That said, I think we can both agree that PA is a fantastic supp and is one of the best I've used personally (SL) and for muscle gains favorably compares to a very lose dose of a mild anabolic such as 10-15mg anavar/day.