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SARM's, MK, & GW : A User's Guide

This is how I used to do it:

"Hi, what would you like to drink?"
"Ice Tea."
"Really!?"
"Yes, I have a bad acid reflux, my doctor told me I need to stop drinking alcohol". :)
 
Any idea how long tudca stays in the system being taking arimicare pro and going to a wedding this weekend and will be drinking
 
foofighter said:
Any idea how long tudca stays in the system being taking arimicare pro and going to a wedding this weekend and will be drinking
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I'd lay off it for the rest of the week.

I can't find the half-life of TUDCA specifically, but orally administered UDCA (metabolite of TUDCA) is 3.5-5.8 days. So, it may be best to stop Arimicare Pro now, and resume dosing the day after drinking.

EDIT: I should have asked why you are on Arimicare PRO to begin with? Def don't want you drinking if you are on anything harsh.
 
The hardest part is trying to keep up appearances from when I was off cycle and drinking. If I want to keep it secret I can't be raising questions of why I quit drinking. While on any oral at all I limit myself to a couple of drinks if and when I go out at all. I try to stay in so I am not tempted.

Just be smart. If you start pissing blood or can't get your pee clear than maybe you should stop drinking on cycle.. Lol
 
rascal14 said:
The hardest part is trying to keep up appearances from when I was off cycle and drinking. If I want to keep it secret I can't be raising questions of why I quit drinking. While on any oral at all I limit myself to a couple of drinks if and when I go out at all. I try to stay in so I am not tempted.

Just be smart. If you start pissing blood or can't get your pee clear than maybe you should stop drinking on cycle.. Lol
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This would be my first cycle of any description and I really wanted to stay alcohol free...hopefully there won't be anything as drastic as passing blood, that would be scary!

Anything else I should watch out for? Blood pressure?

So I will take Milk Thistle and NAC and limit intake to a minimum. Anything else I could/should add?

Thanks.
 
kboxer7 said:
I'd lay off it for the rest of the week.

I can't find the half-life of TUDCA specifically, but orally administered UDCA (metabolite of TUDCA) is 3.5-5.8 days. So, it may be best to stop Arimicare Pro now, and resume dosing the day after drinking.

EDIT: I should have asked why you are on Arimicare PRO to begin with? Def don't want you drinking if you are on anything harsh.
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Finish 5 week run of lgd on sunday...cheers for the info
 
Shin Sprints said:
This would be my first cycle of any description and I really wanted to stay alcohol free...hopefully there won't be anything as drastic as passing blood, that would be scary!

Anything else I should watch out for? Blood pressure?

So I will take Milk Thistle and NAC and limit intake to a minimum. Anything else I could/should add?

Thanks.
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I'll have to look back and see what your cycle is..

I doubt you'll be peeing any blood.. Lol I've done my fair share of drinking on an oral cycle before and was just fine. Not to say it wasn't a dumb idea though.
 
Shin Sprints on just Osta and Dermacrine I think you'll be just fine with standard ACPro dosage only or just take a little extra NAC when you drink if you aren't going with a full on cycle support product. Just be smart and have fun. There's guys on huge amounts of AAS that are addicted to cocaine and drinking and prescription pills out there, one or two nights of light drinking on a light cycle should be the least of your worries, you don't want the worry to ruin your night out.
 
rascal14 said:
I'll have to look back and see what your cycle is..

I doubt you'll be peeing any blood.. Lol I've done my fair share of drinking on an oral cycle before and was just fine. Not to say it wasn't a dumb idea though.
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Plan is 20mg Ostar1ne and 4 pumps Dermacrine for 8 weeks.

First cycle so want to be cautious on all fronts.
 
yates84 said:
It would be best not to drink on cycle. That being said, a couple of beers one night probably won't hurt you. If at all possible I would refrain from drinking if possible
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Make sure you Take NAC the morning before your drinking binge
 
zman86 said:
Haha dang I was about to say...no way One can get bulk 10-15 lbs from a sarm in 4 weeks. Even with LGD, a good bulking run requires 6-8 weeks.
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Rad seems to give more of a recomping effect, my cousin and my best friend both have stayed the same weight on it while seeing body composition changes. They are both running it solo.
 
I'm about 6 weeks in on osta(20mg), cardine(21mg), and dermacrine at 2 pumps morning and 2 pumps evening. Recomping nicely and down about 5lbs, but damn the lethargy is kicking in now. I dunno what it is but I find myself popping two EC stacks just to make it through the day.
 
magicwood said:
I'm about 6 weeks in on osta/cardine/and dermacrine at 2 pumps morning and 2 pumps evening. Recomping nicely and down about 5lbs, but damn the lethargy is kicking in now. I dunno what it is but I find myself popping two EC stacks just to make it through the day.
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Made any big diet changes recently?
 
magicwood said:
I'm about 6 weeks in on osta(20mg), cardine(21mg), and dermacrine at 2 pumps morning and 2 pumps evening. Recomping nicely and down about 5lbs, but damn the lethargy is kicking in now. I dunno what it is but I find myself popping two EC stacks just to make it through the day.
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Lethargy on Dermacrine doesn't sound right. Are your calories extremely low? Or are your carbs low, leading to hypoglycemia from the high dosage Cardarine perhaps?
 
Hastur said:
Lethargy on Dermacrine doesn't sound right. Are your calories extremely low? Or are your carbs low, leading to hypoglycemia from the high dosage Cardarine perhaps?
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Yep. Low carbs and carderine don't mix
 
Weathermark said:
Why not? Major lethargic sides?
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Can possibly drop your blood sugar and put you in a hypoglycemic state. Lethargy, dizziness, lightheaded, fast heart beat are some signs.
 
I'm in a calorific deficit. I'm taking anywhere from 200-300grams of carbs depending on my workout days. Definitely not hypoglycemia. I was cruising along just fine then out of nowhere it hit me. Loving the stack though. OL and BPS are top notch companies. I just have to grind it out for another two weeks then straight into PCT. Hopefully I'll feel better when I bump my calories up during PCT.
 
Just drop the Cardarine to 14, that should help. I really think 21mg is a bit much for most people. 7-14 should be a standard dose.
 
gagandugan said:
Just drop the Cardarine to 14, that should help. I really think 21mg is a bit much for most people. 7-14 should be a standard dose.
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20mg was way too much for me, I like carderine in the 7 to 14mg range for sure. Remember, these aren't underdosed research chemicals you are dealing with
 
Yeah. People will start feeling lethargic, blood sugar will drop, they won't sleep well... which will totally defy the purpose of an endurance booster. I'll use 7mg next month with Norcodrene and Exotherm - and no low carbs! These products are quite potent, I think most people don't realize what 7-14 mg of Cardarine can do. Or only 5mg of Ligandrol.
 
Can people review and give feedback please?

So I 2 weeks I plan on doing first ever cycle. And this is how I have it lined up...

Weeks 1-8...

20mg Ostar1ne
3 pumps of Dermacine (test base)
Inhibit E as per label (estro control)
Hawthorne Berry (BP)
Milk Thistle and NAC (Liver...this is insurance against a night or two that may occur while on and are unavoidable)

Exem on hand in case of Estro flair up...but hope Inhibit E will suffice.

Weeks 9-12...PCT...

Clomid 50/25/25
Super PCT as per label
Ep1c Unleashed

Questions I still have...

I have both Erase Pro and Inhibit E, 2 bottles of each...which product would you recommend for on cycle AI?

Would the AI be best taken from first week, or add in in week 5-8?

There are AIs in Super PCT so would running Inhibit E running into Super PCT be too long on an AI? Would be 12 weeks if I did Inhibit E on cycle weeks 1-8.

Dermcrine application...I work out in the morning. Would be be best to apply 3 pumps after gym shower? Should I split doses, say 2 after gym, one later in the day?

Thanks.
 
Shin Sprints said:
I have both Erase Pro and Inhibit E, 2 bottles of each...which product would you recommend for on cycle AI?
Which version of Erase Pro? The Arimistane Version or the new one? If the new one go with Inhibit E
Would the AI be best taken from first week, or add in in week 5-8?
I would run it the whole time because of the Dermacrine. If it was just Ostarine I would wait until first signs of Estro-sides.
There are AIs in Super PCT so would running Inhibit E running into Super PCT be too long on an AI? Would be 12 weeks if I did Inhibit E on cycle weeks 1-8.
No thats totally fine
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So I got my bottles Endurashred today. As I have much experience with GW and am certain that 21mg+ would be fine since Osta will probably raise my Bloodpressure, how would you suggest starting the cycle?
first week 1 cap, than up to two and a week later maybe to 3 or would you thing starting with 2 would be fine?
I will ad El1minate at the first sign of Estro-sides and have Epistane experience but no SARM-experience.
 
Shin Sprints said:
Can people review and give feedback please?

So I 2 weeks I plan on doing first ever cycle. And this is how I have it lined up...

Weeks 1-8...

20mg Ostar1ne
3 pumps of Dermacine (test base)
Inhibit E as per label (estro control)
Hawthorne Berry (BP)
Milk Thistle and NAC (Liver...this is insurance against a night or two that may occur while on and are unavoidable)

Exem on hand in case of Estro flair up...but hope Inhibit E will suffice.

Weeks 9-12...PCT...

Clomid 50/25/25
Super PCT as per label
Ep1c Unleashed

Questions I still have...

I have both Erase Pro and Inhibit E, 2 bottles of each...which product would you recommend for on cycle AI?

Would the AI be best taken from first week, or add in in week 5-8?

There are AIs in Super PCT so would running Inhibit E running into Super PCT be too long on an AI? Would be 12 weeks if I did Inhibit E on cycle weeks 1-8.

Dermcrine application...I work out in the morning. Would be be best to apply 3 pumps after gym shower? Should I split doses, say 2 after gym, one later in the day?

Thanks.
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Either of those otc ai's will be fine for your cycle. I would go ahead and kick off a low dose of 1 cap from the start. You can adjust your ai dose as the cycle progresses. 12 weeks on an otc ai isn't uncommon, just start with a low dose and you should be gtg. If you're only using 3 pumps I would apply all of it post shower. 3 pumps is pretty easy to apply all at one time and you will get the best absorption after you shower
 
Bunshichi said:
So I got my bottles Endurashred today. As I have much experience with GW and am certain that 21mg+ would be fine since Osta will probably raise my Bloodpressure, how would you suggest starting the cycle?
first week 1 cap, than up to two and a week later maybe to 3 or would you thing starting with 2 would be fine?
I will ad El1minate at the first sign of Estro-sides and have Epistane experience but no SARM-experience.
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That sounds like a good plan since you have prior gw experience. Just remember that this isn't research grade, it is very strong so definitely increase gradually. You can low dose eliminate from the start if you want. Eliminate isn't going to be too much of a help if you are getting high estrogen sides. Don't play around with high estrogen, have exemestane on hand for such situations
 
I always have my SERMs on hand and if I experience estro-sides that seem too much for OTC products I feel I don't want to continue such a cycle and go straight to pct.

If I want to run El1minate from the start do you think 50mg is appropiate?

My GW was from PN and even on 30mg I only had problems taking vasodilators at the same time.
 
Bunshichi said:
I always have my SERMs on hand and if I experience estro-sides that seem too much for OTC products I feel I don't want to continue such a cycle and go straight to pct.

If I want to run El1minate from the start do you think 50mg is appropiate?

My GW was from PN and even on 30mg I only had problems taking vasodilators at the same time.
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50mg of eliminate is a good starting dose. Very interested in your comparison between OL and PN gw, let us know your thoughts!
 
Will try to compare but it might be hard to tell the difference since I will have a stack with Osta now.
Maybe I will pick up a bottle OL Cardarine for PCT and then it will be easy to compare cause I used PN GW in PCT also.
 
yates84 said:
Let's talk Osta....

Ostarine - is, probably, the most well known SARM's. It is best used to preserve muscle mass, while in a caloric deficit. Ostarine can, and will, suppress your natural testosterone production in longer higher dosed cycles. So, a SERM PCT is needed. Ostarine can also cause gyno in some users. So, it is recommended that you have an AI, like Exemestane, on hand. The average cycle length is 6 to 10 weeks at a dosage range of 10mg to 25mg.

Ostarine example cycle:
Beginner cut
Ostarine - 15/15/15/15/15/15
PCT:
OL Super PCT as indicated on label
*AI of choice on hand

Advanced Cut:
Ostarine - 15/15/15/15/15/20/20/20/20/20
OL Eliminate - 2/2/2/2/2/3/3/3/3/3
PCT:
OL Super PCT as indicated on label
Clomid 50/25/25

Recomp cycle:
Ostarine - 20/20/20/20/25/25/25/25
PCT:
OL Super PCT as indicated on label
Clomid 50/25/25


Now, here are some SARM cycle Stacks that I've come up with....

Cut to Bulk:
Ostarine -15/15/15/15/15/15/0/0/0/0
LGD - 0/0/0/0/4/4/8/8/12/12
PCT:
OL Super PCT as indicated on label
Clomid 50/25/25

RAD/Osta Recomp:
RAD - 4/4/8/8/12/12/0/0
Ostarine - 20/20/20/20/25/25/25/25
PCT:
OL Super PCT as indicated on label
Clomid 50/25/25

RAD/LGD Bulk:
RAD - 4/4/8/8/12/12/0/0
LGD - 4/4/4/8/8/8/12/12
PCT:
OL Super PCT as indicated on label
Clomid 50/50/25/25

**MK 677 and/or GW would stack great with these cycles, as well, and would help with endurance, sleep, and overall muscle gain. (Refer to MK 677 and GW dosing at top of thread).**

Coming tomorrow...other PCT options!
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You prefer clomid over nolva for pct?
 
rafy99 said:
You prefer clomid over nolva for pct?
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Though that may be yates84's preference, I believe it is more of an example and a reminder that a SERM is recommended in PCT. There are several SERMs out there one could use for such a purpose as HPTA restart in PCT, I personally prefer Toremifene.
 
Clomid is gonna be better for Hpta restart while nolva is better for estrogen related issues in the aspect both are serms . That's just a simplified version
 
Jokes aside, I may actually try an enema with MK-677. Theoretically, this way you bypass the stomach and it would be delivered into your bloodstream as efficient as IV.
edit: almost as efficient as IV

Thinking about it, it may be a bad idea, because I made the liquid from powdered Ibutamoren in 95% grain alcohol.

This could burn bad...

...but it will give a buzz too... :friday:
 
hairygrandpa said:
Jokes aside, I may actually try an enema with MK-677. Theoretically, this way you bypass the stomach and it would be delivered into your bloodstream as efficient as IV.

Thinking about it, it may be a bad idea, because I made the liquid from powdered Ibutamoren in 95% grain alcohol.

This could burn bad...

...but it will give a buzz too... :friday:
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and what is your goal in doing that? I have a degree in medical field, and I am qualified enough to tell you that no form of drug administration of as effective as intravenous. There is no higher bioavailability than direct shot into blood stream ( not absorbing in our colon walls). Not shoving something up your ass. Best bioavailability in bloodstream is IV (fact). Sorry dude, but unless you need an enema already - that is just weird .
 
muay thai said:
and what is your goal in doing that? I have a degree in medical field, and I am qualified enough to tell you that no form of drug administration of as effective as intravenous. There is no higher bioavailability than direct shot into blood stream ( not absorbing in our colon walls). Not shoving something up your ass. Best bioavailability in bloodstream is IV (fact). Sorry dude, but unless you need an enema already - that is just weird .
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Nobody is talking about intravenously injecting Sarms. My thought is simple. If bypassing the gastric tract can be achieved by rectal administration, why not? It should be more efficient as taking it by mouth.

Quote wiki: A drug that is administered rectally will in general (depending on the drug) have a faster onset, higher bioavailability, shorter peak, and shorter duration than the oral route.
In addition, the rectal route bypasses around two thirds of the first-pass metabolism as the rectum's venous drainage is two thirds systemic (middle and inferior rectal vein) and one third portal (superior rectal vein). This means the drug will reach the circulatory system with significantly less alteration and in greater concentrations. Quote end.
 
Rectal probably would be as the amount of blood vessels etc in the rectal wall compared to under the tongue . But regardless sublingual still bypasses gastric to a degree
 
Joedoubledose said:
Rectal probably would be as the amount of blood vessels etc in the rectal wall compared to under the tongue . But regardless sublingual still bypasses gastric to a degree
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Now my thoughts are circling about somehow combining the sublingual- with the rectal, but that would need at least two people.

LOL

I had too much wine... I better go to sleep.

:toofunny:
 
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