The Official OL UK Cardar1ne Q&A

jmendoza251g said:
Thanks Yates , does everyone take them at once or is anyone spreading them out?
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I have always dosed carderine 1 time a day, first thing in the morning. I'm sure other people dose it differently but I see no reason to do so
 
The Official OL UK Cardar1ne Q&A

yates84 said:
I have always dosed carderine 1 time a day, first thing in the morning. I'm sure other people dose it differently but I see no reason to do so
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If doing IF I feel spacing out may be more beneficial? To avoid hypo sides? Or just move the bolus dose closer to workout..?
 
chedapalooza said:
If doing IF I feel spacing out may be more beneficial? To avoid hypo sides? Or just move the bolus dose closer to workout..?
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I guess you could move some of your dose closer to your workout. It should still have the same effect no matter how you dose it though, as long as it is dosed at least once ed
 
mechka_grizli said:
To my knowledge there hasn't been any human trials on GW has there?
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Yes there has. But we only ever hear about the fact is causes cancer in rodents. Not to mention almost every study I've seen with rodents they gave them huge doseages for their body weight etc.
 
grinnell27 said:
Yes there has. But we only ever hear about the fact is causes cancer in rodents. Not to mention almost every study I've seen with rodents they gave them huge doseages for their body weight etc.
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Yeah that part I know. Just wasn't aware on the human study. I knew about the rodents and monkeys but not this one. I got some reading to do
 
mechka_grizli said:
Yeah that part I know. Just wasn't aware on the human study. I knew about the rodents and monkeys but not this one. I got some reading to do
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Haha yeah, I would link the studies I read but it was a while ago and my browser history has been cleared since then.
 
There definitely have been human studies done on carderine. It almost seems like big pharma gave up on carderine because of the chances of it being abused as a performance drug. I could be way off though
 
yates84 said:
There definitely have been human studies done on carderine. It almost seems like big pharma gave up on carderine because of the chances of it being abused as a performance drug. I could be way off though
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This. As it increases endurance by up to 45% (what I've read) it could be a grey are for marathon runners or sprinter... Well any sport really.
 
grinnell27 said:
This. As it increases endurance by up to 45% (what I've read) it could be a grey are for marathon runners or sprinter... Well any sport really.
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I know wada was all up on it during development
 
They studies it in rats, mice Rhesus Monkeys & humans.

Only the rats got cancer.

Human Studies
Invalid Link Removed

Invalid Link Removed


There are 2 theories as to why GW research was discontinued...

Theory 1: Had something to to with WADA and this being used by athletes for performance enhancement.

The more likely reason...

Theory 2: GW was being research to help with Cholesterol levels. It had such a profound effect on both
lowering bad cholesterol and raising good Cholesterol, GSK (the manufacturer), decided to stop research
because this was just too effective. It had a permanent effect on cholesterol levels. Drug companies are
looking to drugs that people need to take the rest of their lives. This would have cut into profit margins of
other cholesterol drugs that they already sell, and people take daily forever.

To give you an example on this kind of thinking. Nightline or 20/20 (one of those nighttime reporting shows)
had a special on a while back about people contracting infectious bacterias, likestaph and MRSA while
staying in Hospitals around the country.

One of the reasons why these have got so out of hand these bacterias have gotten so out of hand, is that
research into new antibiotics has almost stopped. Most companies have no new antibiotics being researched.

The reason...?

Profit..!

Pharma companies are putting more money, and more research into drugs that people can take long term.

Drugs for Blood Pressure, Drugs for Cholesterol, Pain Management, Diabetes, and other life long illnesses.

The program went on to say that there is no money in Antibiotics, because people only take them for 7-10
days, and then they are done with them. These are drugs that cure an illness, not treat it.

So, the reality is, rather then putting the money into the research of drugs that can cure illness, they would
rather treat illnesses instead, because longterm treatment is more profitable, then shortterm cures.
 
vujade said:
They studies it in rats, mice Rhesus Monkeys & humans.

Only the rats got cancer.

Human Studies
Invalid Link Removed

Invalid Link Removed


There are 2 theories as to why GW research was discontinued...

Theory 1: Had something to to with WADA and this being used by athletes for performance enhancement.

The more likely reason...

Theory 2: GW was being research to help with Cholesterol levels. It had such a profound effect on both
lowering bad cholesterol and raising good Cholesterol, GSK (the manufacturer), decided to stop research
because this was just too effective. It had a permanent effect on cholesterol levels. Drug companies are
looking to drugs that people need to take the rest of their lives. This would have cut into profit margins of
other cholesterol drugs that they already sell, and people take daily forever.

To give you an example on this kind of thinking. Nightline or 20/20 (one of those nighttime reporting shows)
had a special on a while back about people contracting infectious bacterias, likestaph and MRSA while
staying in Hospitals around the country.

One of the reasons why these have got so out of hand these bacterias have gotten so out of hand, is that
research into new antibiotics has almost stopped. Most companies have no new antibiotics being researched.

The reason...?

Profit..!

Pharma companies are putting more money, and more research into drugs that people can take long term.

Drugs for Blood Pressure, Drugs for Cholesterol, Pain Management, Diabetes, and other life long illnesses.

The program went on to say that there is no money in Antibiotics, because people only take them for 7-10
days, and then they are done with them. These are drugs that cure an illness, not treat it.

So, the reality is, rather then putting the money into the research of drugs that can cure illness, they would
rather treat illnesses instead, because longterm treatment is more profitable, then shortterm cures.
Click to expand...

^^this makes way too much sense
 
The Official OL UK Cardar1ne Q&A

yates84 said:
^^this makes way too much sense
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Definitely an interesting conspiracy theory (serious), although it needs more samuel L Jackson and people getting murdered.

Isn't that what pharma companies do when some super smart scientist discovers something groundbreaking. Coincidentally they accidentally drink some radioactive tea or go on permanent holidays to Madagascar?
 
I am currently using Legend (LGD) and have an unopened bottle of Cardar1ne. Would it be better to start stacking the two and continue the GW through PCT or start the GW at the beginning of PCT and continue it solo four weeks post PCT?
 
muscle inc. said:
I am currently using Legend (LGD) and have an unopened bottle of Cardar1ne. Would it be better to start stacking the two and continue the GW through PCT or start the GW at the beginning of PCT and continue it solo four weeks post PCT?
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I would stack them, you will get better effect from the gw while on anabolics imo. I like gw in pct just for the fact that it helps regulate my bp, something I have struggled with in some of my past pct's
 
muscle inc. said:
I am currently using Legend (LGD) and have an unopened bottle of Cardar1ne. Would it be better to start stacking the two and continue the GW through PCT or start the GW at the beginning of PCT and continue it solo four weeks post PCT?
Click to expand...

Ill be stacking mine in the second half of my cycle and through pct till it runs out
 
Re: The rats, they were given a daft dose for a very long time just to test for side effects.
Run it with Alcar for increased effect, just watch out for the dry throat.
 
UPDATE:


1) Yesterday (Wed., August 5th) was day 15 on Cardarine, day 8 @ 21 mg.

2) time during training was unchanged from the week before, but I did recover faster and more completely between sets. So, I could have pushed myself to reduce my time, no problem, but it was just one of those days where I didn't have my usual "zip" in the gym.

3) nevertheless, I increased the weight in 2 movements, kept 2 the same but completed 1 more rep on the last set of the last movement. All-in-all, a very productive workout

4) fat loss is DEFINITELY accelerated; numerous people are noticing, yet weight remains basically unchanged.

5) next phase will probably be to reduce calories and carbs further for an even more rapid and dramatic effect.
 
Thank you guys, stack it is. Been on MK-677 for 5 weeks, LGD for two weeks, now adding in the GW. Already amazing but only going to get better.
 
Got my stuff sorted out... Going to wait til October to run cardar1ne since I'm slowly reverse dieting; I don't want to take it with less than 100g daily carbs. I'll be at 125-150g in October and still climbing so I figure thT will be the perfect time to throw it in to this stack:

September: coming off clomid; add in letrone 1 cap, ghar1ne 10mg nightly

October: letrone 1 cap, ghar1ne 20mg, Cardar1ne building up to 14mg

November: probably drop the ai/have one on hand based off blood work, ghar1ne 30mg, cardar1ne 14-21mg based on effects

December: drop ghar1ne, cardar1ne 14-21mg

All will most likely include ep1c unleashed and cycle LJ 100 at 6 weeks on/2 weeks off. Seems to be an effective method for me based off my recent blood work!

Then in January I'd start all over again :)
 
chedapalooza said:
Got my stuff sorted out... Going to wait til October to run cardar1ne since I'm slowly reverse dieting; I don't want to take it with less than 100g daily carbs. I'll be at 125-150g in October and still climbing so I figure thT will be the perfect time to throw it in to this stack:

September: coming off clomid; add in letrone 1 cap, ghar1ne 10mg nightly

October: letrone 1 cap, ghar1ne 20mg, Cardar1ne building up to 14mg

November: probably drop the ai/have one on hand based off blood work, ghar1ne 30mg, cardar1ne 14-21mg based on effects

December: drop ghar1ne, cardar1ne 14-21mg

All will most likely include ep1c unleashed and cycle LJ 100 at 6 weeks on/2 weeks off. Seems to be an effective method for me based off my recent blood work!

Then in January I'd start all over again :)
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Sounds great man. Are you keeping a log on here somewhere?
 
Today is my third day taking 7mg, is it worth sticking at 7mg for a week or two or should I go straight to 14mg?

Also last night before I went to bed I got really dizzy, even lasted when I laid down and was trying to go to sleep. Pretty strong, head spinning kind of dizzy. All day yesterday and today I've been fine. Any ideas if it could be related?
 
Anyone interested: OL UK site is up and ready to go! Use OLYMPUSUK30 at checkout for 30% off Invalid Link Removed so u can pick this up for pretty cheap right now!
 
UPDATE:

1) today (Fri., August 7th) was day 17 on Cardarine, day 10 @ 21 mg.

2) training time was unchanged, but I added weight to 3 movements, 1 stayed the same but I was able to add a rep to each set.

3) I'm recovering faster not only between sets, but after training. I feel fresher, less drained despite adding weight consistently while in a caloric deficit.

4) fat loss is very discernable at this point, yet I feel constantly pumped and full.
 
crowbar46 said:
UPDATE:

1) today (Fri., August 7th) was day 17 on Cardarine, day 10 @ 21 mg.

2) training time was unchanged, but I added weight to 3 movements, 1 stayed the same but I was able to add a rep to each set.

3) I'm recovering faster not only between sets, but after training. I feel fresher, less drained despite adding weight consistently while in a caloric deficit.

4) fat loss is very discernable at this point, yet I feel constantly pumped and full.
Click to expand...

Thanks for you continuous and detailed updates!
It's much appreciated :)
 
Have 2 bottles on hand and ready to run. Doing a keto diet now, should I save this when I have more carbs in my diet?
 
thank you to all the folks posting detailed reviews so far

NVerse is out of stock - I will do a double bottle run when they restock - and have my gf start out at 7mg per day ( she is a npc bikini competitor). She has endometreosis and fibromyalgia , her energy levels are forever absent.
I will post her feedback - perhaps she should stop the bronkaid then to give accurate
she is also on ostarine, and has used it a few times and knows the difference between the results it would exhibit vs cardarine
 
vujade said:
They studies it in rats, mice Rhesus Monkeys & humans.

Only the rats got cancer.

Human Studies
Invalid Link Removed

Invalid Link Removed


There are 2 theories as to why GW research was discontinued...

Theory 1: Had something to to with WADA and this being used by athletes for performance enhancement.

The more likely reason...

Theory 2: GW was being research to help with Cholesterol levels. It had such a profound effect on both
lowering bad cholesterol and raising good Cholesterol, GSK (the manufacturer), decided to stop research
because this was just too effective. It had a permanent effect on cholesterol levels. Drug companies are
looking to drugs that people need to take the rest of their lives. This would have cut into profit margins of
other cholesterol drugs that they already sell, and people take daily forever.

To give you an example on this kind of thinking. Nightline or 20/20 (one of those nighttime reporting shows)
had a special on a while back about people contracting infectious bacterias, likestaph and MRSA while
staying in Hospitals around the country.

One of the reasons why these have got so out of hand these bacterias have gotten so out of hand, is that
research into new antibiotics has almost stopped. Most companies have no new antibiotics being researched.

The reason...?

Profit..!

Pharma companies are putting more money, and more research into drugs that people can take long term.

Drugs for Blood Pressure, Drugs for Cholesterol, Pain Management, Diabetes, and other life long illnesses.

The program went on to say that there is no money in Antibiotics, because people only take them for 7-10
days, and then they are done with them. These are drugs that cure an illness, not treat it.

So, the reality is, rather then putting the money into the research of drugs that can cure illness, they would
rather treat illnesses instead, because longterm treatment is more profitable, then shortterm cures.
Click to expand...

I just wanted to comment on the whole 'cancer' bit, which is what worries a lot of people who hear about Cardarine/GW-501516. All studies showing an incidence of cancer from GW-501516 included DMBA, which is a carcinogen in and of itself and accelerates cancer growth in studies. But usually there are signs of potential cancer development without DMBA, and in the studies everything was fine within reasonable dosage protocols.

In one study, which I am trying to track down again, it showed:
DMBA - X tested; 0 cancer
GW-501516 - X tested; 0 cancer
DMBA + GW - X tested; X cancer

It appears it was not GW-501516 alone that caused cancer, and the fear continued to get out of hand following the WADA letter. In fact, the company that produced GW-501516 continued their research with human clinical trials after the cancer/polyps study in mice, so clearly it didn't bother them, and no such side effects regarding cancer or polyps were reported with the humans.

Also, I want to touch on one of the potential concerns in the past which was that GW-501516 prevents cell apoptosis (programmed cell death, which is one of the ways that your body prevents cancer) which I believe was tied to COX-2 stimulation by GW-501516 (correct me if I'm wrong). This is why you'll see suggestions online in various forums recommending that you stack Cardarine/GW-501516 with a COX-2 inhibitor such as Tribulus Terrestris which was shown to have strong inhibitory activity on COX-2. As the study below shows:

"Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells."
Invalid Link Removed

I personally would stack Tribulus Terrestris with Cardar1ne just to be safe, but I have zero concern using Cardar1ne in regards to its effects on my health and well-being.
 
Hastur said:
I just wanted to comment on the whole 'cancer' bit, which is what worries a lot of people who hear about Cardarine/GW-501516. All studies showing an incidence of cancer from GW-501516 included DMBA, which is a carcinogen in and of itself and accelerates cancer growth in studies. But usually there are signs of potential cancer development without DMBA, and in the studies everything was fine within reasonable dosage protocols.

In one study, which I am trying to track down again, it showed:
DMBA - X tested; 0 cancer
GW-501516 - X tested; 0 cancer
DMBA + GW - X tested; X cancer

It appears it was not GW-501516 alone that caused cancer, and the fear continued to get out of hand following the WADA letter. In fact, the company that produced GW-501516 continued their research with human clinical trials after the cancer/polyps study in mice, so clearly it didn't bother them, and no such side effects regarding cancer or polyps were reported with the humans.

Also, I want to touch on one of the potential concerns in the past which was that GW-501516 prevents cell apoptosis (programmed cell death, which is one of the ways that your body prevents cancer) which I believe was tied to COX-2 stimulation by GW-501516 (correct me if I'm wrong). This is why you'll see suggestions online in various forums recommending that you stack Cardarine/GW-501516 with a COX-2 inhibitor such as Tribulus Terrestris which was shown to have strong inhibitory activity on COX-2. As the study below shows:

"Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells."
Invalid Link Removed

I personally would stack Tribulus Terrestris with Cardar1ne just to be safe, but I have zero concern using Cardar1ne in regards to its effects on my health and well-being.
Click to expand...

Which tribulus product do you recommend?
 
Hastur said:
I just wanted to comment on the whole 'cancer' bit, which is what worries a lot of people who hear about Cardarine/GW-501516. All studies showing an incidence of cancer from GW-501516 included DMBA, which is a carcinogen in and of itself and accelerates cancer growth in studies. But usually there are signs of potential cancer development without DMBA, and in the studies everything was fine within reasonable dosage protocols.

In one study, which I am trying to track down again, it showed:
DMBA - X tested; 0 cancer
GW-501516 - X tested; 0 cancer
DMBA + GW - X tested; X cancer

It appears it was not GW-501516 alone that caused cancer, and the fear continued to get out of hand following the WADA letter. In fact, the company that produced GW-501516 continued their research with human clinical trials after the cancer/polyps study in mice, so clearly it didn't bother them, and no such side effects regarding cancer or polyps were reported with the humans.

Also, I want to touch on one of the potential concerns in the past which was that GW-501516 prevents cell apoptosis (programmed cell death, which is one of the ways that your body prevents cancer) which I believe was tied to COX-2 stimulation by GW-501516 (correct me if I'm wrong). This is why you'll see suggestions online in various forums recommending that you stack Cardarine/GW-501516 with a COX-2 inhibitor such as Tribulus Terrestris which was shown to have strong inhibitory activity on COX-2. As the study below shows:

"Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells."
Invalid Link Removed

I personally would stack Tribulus Terrestris with Cardar1ne just to be safe, but I have zero concern using Cardar1ne in regards to its effects on my health and well-being.
Click to expand...

Great explanation and write-up!
Very informative!!
 
clown007 said:
Great explanation and write-up!
Very informative!!
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Thanks, bro! I want to make sure everyone has as much accurate information as possible to make the best decision for themselves, and there is a lot of confusing misinformation out there that can lead people astray!
 
Hastur said:
Really, any Tribulus product should do the job, judging by the paper. I would go with the most economical purchase you can!
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What about something like Rauwolfia Serpentina...since this is what i planned on using as a sub for traditional tribulus?
 
thu_hobbit said:
What about something like Rauwolfia Serpentina...since this is what i planned on using as a sub for traditional tribulus?
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I couldn't find any information leading me to believe that Rauwolfia Serpentina is a COX-2 inhibitor, so I don't see why you would swap them.
 
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