the problem in my opinion, is that each substance can have different effects on each individual. there are people that absorb less or vice versa, (whether oral or by enzymatic conversion cutaneous, etc.), or the dosage of the compound itself may imply very. resveratrol in high doses inhibits the absorption of certain minerals such as iron and copper, thereby causing malfunctions. Copper plays an important role in the metabolism of cartillagine of bones and skin, thus a deficiency may imply a negative effect on the joints. resveratrol acts as an agonist or antagonist of estrogen then this may affect the joints, but this varies depending of the individual, not all metabolize a compound in the same way, and each of us reacts differently. for this reason, in my opinion, is difficult to determine exactly the cause of certain side effects ...
