Grayson
Well-known member
Thanks, brother!
I figured a serm would be needed.
Never used one, but I'm looking into torem.
Ostarine Questions
- Thread starter papapudgy
- Start date
Thanks, brother!
I figured a serm would be needed.
Never used one, but I'm looking into torem.
Tagger
Well-known member
kissdadookie
Well-known member
Goodness sakes, just use a SERM people. LoL. Clomid works well, you can use it as a bridge as well dosed EOD @ around 25 mgs.
I don't understand the mentality, perfectly ok with taking androgens but then shying away from SERMs.
I don't understand the mentality, perfectly ok with taking androgens but then shying away from SERMs.
Contaygious
Active member
I have Nolva but can understand using moneygram can feel shady...
kissdadookie
Well-known member
Moneygram? What? There's so many peptide/re-chem sites that uses credit cards. LoL.
Grayson
Well-known member
Unless getting it from an indian pharma site, just find an rc company (preferably one that has a board presence) and go to town.
Chemical synthesis of most SERMs aren't that difficult.
Tagger
Well-known member
Creepy, but I like it!
xhrr
Well-known member
Nolva I all I ever used so I can only comment on that but I've always been satisfied
Tagger
Well-known member
Same here and I am a firm believer of don't fix what's not broken.
Contaygious
Active member
Well if you are used to getting real stuff those sources also carry the serms. Thats where im used to getting. Not sure I trust using a cc online to order illegal things just yet myself. Might as well get it there while you order your gear anyway.
Tagger
Well-known member
Well technically research chems like Nolva are legal.
As long as you give them to your rat, just like all of us other guys do
Goliath1
Banned
Torem will work if it's legit, I like Torem personally..
Torem Nolva Clomid They all work.
Agreed... I've tried them all & Ralox..
What's wrong with serms from India?
I got a whole bunch of them brotha!!
Contaygious
Active member
Well technically research chems like Nolva are legal.
As long as you give them to your rat, just like all of us other guys do
Word so how do we get research gear for our rats when that new bill passes the senate?
Grayson
Well-known member
Stock up, for the end is near.
Contaygious
Active member
Well the ug will be around! Doubt you can use chem sites anymore. Plus ug prices seem better anyway.
Swolljaboi
Active member
Are we sure that the new bill will even affect chem sites since their products aren't intended for human consumption?
goodvibes
Well-known member
Right? I almost checked out using my cc but damn there were way too many disclaimers. I was like nah... Cnt afford the risk.
funding31213
New member
How would you guys compare osta to other anabolic in terms of how it affects your mood? I haven't heard any comparisons yet. I'm in week six and I feel more positive and less quick to get angry
Contaygious
Active member
I think its the best my mood has been in a long time. Aas can make ya kinda pissy
Tagger
Well-known member
Tagger
Well-known member
It's probably because I've never ordered from there cause of the horror stories.
I do the whole reviews thing and buy haha.
Tagger
Well-known member
Yah I was.
Tagger
Well-known member
I think Osta really just helps your body adapt to what gainz you made on cycle.
Since you shouldn't run long term PHs (which would help solidify gainzzz) Osta enables you to do that.
xhrr
Well-known member
I might at most lose a lb and five lbs on a lift or a rep but no more than that. When I run it at lower doses I never lose anything it's only 25mg or higher I noticed minuscule drop offs. Still better than pre cycle though. I know guys who run ridiculous cycles of aas and ph and can rep out 300+ on bench while on but can't touch 300 when off. I would never want that I want maintainable cycles and Osta definitely is.
Tagger
Well-known member
Grayson
Well-known member
Alright new question:
Does anyone have any studies/references on the increased protein synthesis of Ostarine? If it acts like an aas (just not as strongly) it should substantially increase it, thus efficiently utilizing the protein a lot of us use in a bulk (we're talking 1.5-3g/lb).
Tangentially, it might lower the carb requirements in a hypercaloric environment necessary for lbm gains.
Does anyone have any studies/references on the increased protein synthesis of Ostarine? If it acts like an aas (just not as strongly) it should substantially increase it, thus efficiently utilizing the protein a lot of us use in a bulk (we're talking 1.5-3g/lb).
Tangentially, it might lower the carb requirements in a hypercaloric environment necessary for lbm gains.
Tagger
Well-known member
No but I am going to look into this.
kissdadookie
Well-known member
For all intent and purposes, it's basically a steroid but the special thing it does is that it has a selective affinity to bone and muscle cells thus giving you less of an impact on organs growth (and probably due to that, your body overall sense less exogenous androgens thus you don't get supressed as badly and anecdotally, can recovery from supression easier). The strength of it's effects appears to be dose dependent.
snagencyV2.0
Legend
I understand the point & comparison you attempt to make here, and you are not the only one that does this..
but it is not a steroid, and I don't feel such faulty comparisons do anyone justice
here's a pretty good summary and instruction of osta, pretty descriptive, should answer all questions
Invalid Link Removed
Ostarine (also known as: MK-2866, Enobosarm)
ostarine mk-2866
What is Ostarine?
MK-2866 Ostarine bottleOstarine (MK-2866) is a SARM developed by GTx for the prevention and treatment of muscle wasting. It may eventually be a medical prescription for the prevention of cachexia, atrophy and sarcopenia as well as for Hormone or Testosterone Replacement Therapy.
As a research chemical, Ostarine belongs to a class of chemicals know as SARMS or selective androgen receptor modulators. SARMS create selective anabolic activity at certain androgen receptors. In comparison to testosterone and other anabolic steroids, the advantage of SARMS, is they do not have androgenic activity in non-skeletal muscle tissues. Ostarine is effective in maintaining and increasing lean body mass.
How does it work?
SARMS bind to the androgen receptor and demonstrate osteo (bone) and myo (muscular) anabolic activity.
Androgen receptor activation
Binding and activation of the Androgen receptor alters the expression of genes and increases protein synthesis which builds muscle. In essence, SARMS like ostarine cause muscle growth in the same manner as steroids, however unlike testosterone and other anabolic steroids, SARMS do not produce the growth effect on prostate and other secondary sexual organs.
Ostarine in particular exerts its anabolic effects on muscle tissue almost exclusively. So not only does it represent a new potential treatment option for a wide spectrum of conditions from muscle wasting diseases (from age-related to AIDS or cancer-related), but is also has immense potential for muscle building for bodybuilders, fitness, athletes and an agent to minimize atrophy during recovery periods from serious surgery or similar situations.
*Uses of Ostarine*
Lean muscle gains (bulking)
Ostarine is the most anabolic of any SARMS, making its first and foremost use for wanting to gain lean muscle. The gains in total weight will not be comparable to bulking steroids, however the total gains will almost entirely be lean muscle.
The gains that are made on ostarine are very keepable and users generally see an increase of up to 7 lbs. of lean body mass over and 8 week cycle at 25mg day (diet dependent). The most common dosage is 25 mg for 8 weeks. The side effects that one encounters with steroid use will not be present on cycle.
Generally, with ostarine, the higher the dosage, the more suppression. Although suppression is minimal and is nowhere comparable to suppression that one encounters on steroids, any cycle of ostarine over a 4 weeks period requires a 3 week mini pct. A serm is not required in this pct.
Losing Bodyfat (cutting)
Ostarine would primarily fit into a cutting protocol for the maintenance of muscle mass while reducing calories. One of the most disheartening outcomes of cutting is the loss hard earned muscle mass. The drop in metabolic rate and hormone levels (T3, IGF, Testosterone etc) with the lack of calories is a perfect catabolic environment for loss of muscle tissue. As Ostarine has anabolic effects, the dieter can cut calories without having to worry about muscle or strength loss. Ostarine has also shown noticeable nutrient partitioning effects among users, another reason why it can be of great help when cutting.
A 15-20 mg dosing protocol for 6-8 weeks is good for cutting with Ostarine without undergoing any side effects or high suppression. However it must be stated that due to the lack of androgenicity, muscle hardness and overall results are not as prominent as with the SARM S-4.
Recomping
Recomping is where ostarine truly shines. The recomping effect of losing fat and gaining muscle at the same time is what the majority of users are looking for. Trying to achieve this when you are not absolutely new to training is extremely difficult.
Where Ostarine shines for recomping is in its nutrient partitioning benefits. Calories are taken from fat stores and calorie intake is fed to the muscle tissue. In fact many users report that Ostarine consumed at maintenance calories produces weight loss, while still getting increases in strength and muscle mass.
One of the most important factors of recomping is time. As you are trying to achieve multiple objectives, it requires a longer time period to notice good recomp effects so even when running steroids, these would have to be longer run injectable compounds as opposed to the short used liver toxic oral steroids.
Although Ostarine is taken orally, it is not methylated and is not toxic to the liver and does not have a negative effect on ones blood pressure. Therefore it can be run for longer than oral steroids.
The dosing protocol of 20-25mg for 6-8 weeks will give excellent recomp effects.
Diet must also be optimized to where calories are just above maintenance with at least 30% coming from lean sources of protein to get the best recomp effect.
Injury Prevention
The effects of ostarine translate to anabolism in bone and skeletal muscle tissue, which means it could be used in the future for a variety of uses, such as osteoporosis and as a concurrent treatment with drugs that reduce bone density. Therefore it has great application as a compound to use for rehabilitation of injuries, in particular bone and tendon related injuries.
Doses of 12.5mg per day is recommend for such purposes and improvement in joint movement that can be seen after just 6-8 days.
Timing of Doses
As Ostarine has a half life of around 24 hours, each of these doses only has to be taken orally once a day, therefore its also offers an extremely convenient supplementation intake.
Ostarine and estrogen concern
SARMS do not aromatize, conferring all their effects to AR binding and not to metabolic conversion to active androgens/estrogens. However blood work from users has shown a slight elevation in serum estradiol levels (which may be one of the factors in its high effectiveness for treating tendon, ligament, and bone injuries or illnesses.
This elevation is extremely small and is no case for concern. If however you are absolutely concerned about slight increases in Estrogen, you can always opt for low doses AI’s, like aromasin or arimidex for added protection and prevention.
Advantages of Ostarine when compared to steroids
It is non methylated so it is non toxic to the liver or blood pressure Some suppression may be present at doses of 25mg+ run for longer than 4 weeks, however a stringent PCT of prescription SERMs like Nolvadex or Clomid is not necessary. High oral bioavailability without significant damage to your liver as with oral steroids. Great sense of well being while on, (without the aggression which can often detrimentally impact users daily lives). No need for a long time period off between cycles; the recommended time of period for normal steroid cycles would be Time on + PCT, so for a typical 6 week cycle and 4 week PCT, a user would have to wait another 10 weeks after PCT to start another cycle where SARMS recovery requires minimal rest in between. Ostarine also resulted in a dose-dependent decrease in LDL and HDL cholesterol levels, with the average LDL/HDL ratio for all doses remaining in the low cardiovascular risk category – hence there is little impact on cholesterol values. Advantages Of Ostarine when compared to other SARMS
The metabolite M1 which seems to cause toxicity in S4 (temporary occular disturbances) is not present in Ostarine. Also unlike S4, Ostarine does not have androgenic properties in non muscle tissue. Ostarine Summary
Anabolic even at doses as low as 3mg Great for strength Great for lean mass gains Great for body recomposition Great for endurance (aerobic or anaerobic) Joint healing abilities Half life of circa 24 hours – only once a day dosing required Invalid Link Removed
Grayson
Well-known member
I understand the point & comparison you attempt to make here, and you are not the only one that does this..
but it is not a steroid, and I don't feel such faulty comparisons do anyone justice
here's a pretty good summary and instruction of osta, pretty descriptive, should answer all questions
Invalid Link Removed
Ostarine (also known as: MK-2866, Enobosarm)
ostarine mk-2866
What is Ostarine?
MK-2866 Ostarine bottleOstarine (MK-2866) is a SARM developed by GTx for the prevention and treatment of muscle wasting. It may eventually be a medical prescription for the prevention of cachexia, atrophy and sarcopenia as well as for Hormone or Testosterone Replacement Therapy.
As a research chemical, Ostarine belongs to a class of chemicals know as SARMS or selective androgen receptor modulators. SARMS create selective anabolic activity at certain androgen receptors. In comparison to testosterone and other anabolic steroids, the advantage of SARMS, is they do not have androgenic activity in non-skeletal muscle tissues. Ostarine is effective in maintaining and increasing lean body mass.
How does it work?
SARMS bind to the androgen receptor and demonstrate osteo (bone) and myo (muscular) anabolic activity.
Androgen receptor activation
Binding and activation of the Androgen receptor alters the expression of genes and increases protein synthesis which builds muscle. In essence, SARMS like ostarine cause muscle growth in the same manner as steroids, however unlike testosterone and other anabolic steroids, SARMS do not produce the growth effect on prostate and other secondary sexual organs.
Ostarine in particular exerts its anabolic effects on muscle tissue almost exclusively. So not only does it represent a new potential treatment option for a wide spectrum of conditions from muscle wasting diseases (from age-related to AIDS or cancer-related), but is also has immense potential for muscle building for bodybuilders, fitness, athletes and an agent to minimize atrophy during recovery periods from serious surgery or similar situations.
*Uses of Ostarine*
Lean muscle gains (bulking)
Ostarine is the most anabolic of any SARMS, making its first and foremost use for wanting to gain lean muscle. The gains in total weight will not be comparable to bulking steroids, however the total gains will almost entirely be lean muscle.
The gains that are made on ostarine are very keepable and users generally see an increase of up to 7 lbs. of lean body mass over and 8 week cycle at 25mg day (diet dependent). The most common dosage is 25 mg for 8 weeks. The side effects that one encounters with steroid use will not be present on cycle.
Generally, with ostarine, the higher the dosage, the more suppression. Although suppression is minimal and is nowhere comparable to suppression that one encounters on steroids, any cycle of ostarine over a 4 weeks period requires a 3 week mini pct. A serm is not required in this pct.
Losing Bodyfat (cutting)
Ostarine would primarily fit into a cutting protocol for the maintenance of muscle mass while reducing calories. One of the most disheartening outcomes of cutting is the loss hard earned muscle mass. The drop in metabolic rate and hormone levels (T3, IGF, Testosterone etc) with the lack of calories is a perfect catabolic environment for loss of muscle tissue. As Ostarine has anabolic effects, the dieter can cut calories without having to worry about muscle or strength loss. Ostarine has also shown noticeable nutrient partitioning effects among users, another reason why it can be of great help when cutting.
A 15-20 mg dosing protocol for 6-8 weeks is good for cutting with Ostarine without undergoing any side effects or high suppression. However it must be stated that due to the lack of androgenicity, muscle hardness and overall results are not as prominent as with the SARM S-4.
Recomping
Recomping is where ostarine truly shines. The recomping effect of losing fat and gaining muscle at the same time is what the majority of users are looking for. Trying to achieve this when you are not absolutely new to training is extremely difficult.
Where Ostarine shines for recomping is in its nutrient partitioning benefits. Calories are taken from fat stores and calorie intake is fed to the muscle tissue. In fact many users report that Ostarine consumed at maintenance calories produces weight loss, while still getting increases in strength and muscle mass.
One of the most important factors of recomping is time. As you are trying to achieve multiple objectives, it requires a longer time period to notice good recomp effects so even when running steroids, these would have to be longer run injectable compounds as opposed to the short used liver toxic oral steroids.
Although Ostarine is taken orally, it is not methylated and is not toxic to the liver and does not have a negative effect on ones blood pressure. Therefore it can be run for longer than oral steroids.
The dosing protocol of 20-25mg for 6-8 weeks will give excellent recomp effects.
Diet must also be optimized to where calories are just above maintenance with at least 30% coming from lean sources of protein to get the best recomp effect.
Injury Prevention
The effects of ostarine translate to anabolism in bone and skeletal muscle tissue, which means it could be used in the future for a variety of uses, such as osteoporosis and as a concurrent treatment with drugs that reduce bone density. Therefore it has great application as a compound to use for rehabilitation of injuries, in particular bone and tendon related injuries.
Doses of 12.5mg per day is recommend for such purposes and improvement in joint movement that can be seen after just 6-8 days.
Timing of Doses
As Ostarine has a half life of around 24 hours, each of these doses only has to be taken orally once a day, therefore its also offers an extremely convenient supplementation intake.
Ostarine and estrogen concern
SARMS do not aromatize, conferring all their effects to AR binding and not to metabolic conversion to active androgens/estrogens. However blood work from users has shown a slight elevation in serum estradiol levels (which may be one of the factors in its high effectiveness for treating tendon, ligament, and bone injuries or illnesses.
This elevation is extremely small and is no case for concern. If however you are absolutely concerned about slight increases in Estrogen, you can always opt for low doses AI’s, like aromasin or arimidex for added protection and prevention.
Advantages of Ostarine when compared to steroids
Advantages Of Ostarine when compared to other SARMS
Ostarine Summary
Invalid Link Removed
Awesome info. I've read this before.
I know that its majoring in the minors, but just as how those on aas/ph increase protein intake, those on sarms should do the same. However, where's the point of diminishing returns? Meaning that, if bulking with ostarine, and someone is carb-sensitive even with low-bf levels, we can utilize the increased protein synthesis to switch carb calories with protein calories and make the rest up with fat making for a more efficient bulk.
kissdadookie
Well-known member
One thing it's going to do is improve glycogen retention in muscles by a significant amount, why would you try to lower your carbs? If anything, you would be able to utilize carbs better thus can increase it and re-asses where your carb tolerance threshold is.
Grayson
Well-known member
Ah, interesting. I didn't see that way. It would make sense then because I utilized ostarine during the carb load portion of a cyclical diet and noticed I had way better glycogen retention with it than with out it.
kissdadookie
Well-known member
As far as your muscles are concerned, it's an exogenous androgen and it's going to do most of the things that androgens do in terms of growth
Tagger
Well-known member
I think that's why a lot of people bulk on it.
3RT
New member
Same thing for me, energy is through the roof!
I'm running it solo, just to c how I respond.
So far so good!
At 30mg/day......3rd week.....
I'm impressed...
How would you compare this to your anavar cycles? Effects and dosage wise. Also do you log/review your osta experience? I'm going to use it for my girl, so any female input is appreciated.
The intention is bulking after upcoming competitive season @10mg for 7wk then 1wk @5mg, so 8 weeks total. Modest dosage as you see, but seems legit to me for girl on the first cycle. Also looking into laxo and probably ep1c, but osta atm is of the most interest.
kissdadookie
Well-known member
It's technically not a steroid but it does a lot of the good things we would take steroids with, of course people bulk with it
Going to run 8 weeks of it in a month or so. 24 mg's a day. Yeah buddy!
blacklac
Well-known member
It's technically not a steroid but it does a lot of the good things we would take steroids with, of course people bulk with it
Going to run 8 weeks of it in a month or so. 24 mg's a day. Yeah buddy!
Plan your PCT yet?
kissdadookie
Well-known member
Clomid, nolva, letro (just in case). There was a good sale recently
Not going to use it all, but I bought the stuff to take advantage of the sale.
blacklac
Well-known member
Clomid, nolva, letro (just in case). There was a good sale recently
Nice. Always good to have on hand. I'd have prob grabbed some Nolva if I knew. :/